背景:使用基于多核苷酸的产品促进真皮再生和振兴的注射程序正在稳步发展,然而,没有结构化的方案,讨论和提供指导的美学治疗与高度纯化的多核苷酸。本文件的目的是提供基于共识的建议,以安全有效地使用多核苷酸高纯技术™(PN-HPT™)设备进行嫩肤。
方法:一个由八名专家组成的团队,在皮肤恢复和恢复方面具有丰富的经验,整合了现有的最佳证据和临床判断,并设计了一系列实践指导来支持皮肤科医生,整形外科医生,和美学医师使用PN-HPT™产品,单独和组合,在审美医学中。
结果:对于大多数项目,专家组达成了多数共识。对面部达成了“建议”(共识>80%),眼周区域,décolleté和脖子,手,头皮,还有妊娠纹.建议包括技术细节,关于剂量的信息,要注射的体积,以及理想的治疗次数,以及面部和身体不同区域的时间间隔。与面部的初始治疗周期相关的项目达成了较低的60%的一致水平,导致该领域的“共识声明”,而不是完整的“建议”。\"
结论:专家共识说明了自然起源的价值,高度纯化的多核苷酸(PN-HPT™)作为用于皮肤启动和面部和身体恢复的生物刺激增强策略,并提供了详细的使用指南。
BACKGROUND: Injective procedures using
polynucleotides-based products to promote dermal rejuvenation and revitalization are steadily evolving, yet no structured protocols are available that discuss and provide guidance in aesthetic treatments with highly purified
polynucleotides. The goal of this document was to provide consensus-based recommendations for the safe and effective use of
Polynucleotides Highly Purified Technology™ (PN-HPT™) devices for skin rejuvenation.
METHODS: A team of eight experts with extensive experience in treatments for skin rejuvenation and revitalization integrated the best available evidence and clinical judgment and devised a series of practical guidance to support dermatologists, plastic surgeons, and aesthetic physician in the use of PN-HPT™ products, alone and in combination, in aesthetic medicine.
RESULTS: For most items, the expert group achieved a majority
consensus. \"Recommendations\" (consensus >80%) were reached for the face, periocular area, décolleté and neck, hands, scalp, and stretch marks. Recommendations include details of techniques, information on dosage, volumes to be injected, and the ideal number of required treatment sessions, as well as time intervals between them for different areas of face and body. A lower agreement level of 60% was reached on but one item related to the initial treatment cycle for the face, leading to a \"Consensus statement\" for that area instead of a full \"Recommendation.\"
CONCLUSIONS: The expert consensus illustrates the value of natural-origin, highly purified
polynucleotides (PN-HPT™) as biostimulatory booster strategy for skin priming and revitalization of face and body and provides a detailed guide for the use.