open surgery

开放手术
  • 文章类型: Journal Article
    背景:先前已经报道了内窥镜切除血管异常(VA)。然而,没有研究比较儿童内镜切除手术(ERS)和开放切除手术(ORS).我们旨在比较两种方法在小儿VA中的临床和美容结果。
    方法:在2018年6月至2023年6月之间,对138例接受ERS或ORS的儿科VA患者进行了回顾性分析。进行倾向评分匹配(PSM)以最大程度地减少选择偏差。采用基于患者满意度的瘢痕记忆评价量表(SCAR)和数字评定量表(NRS)进行美容评价。
    结果:在PSM年龄之后,病变深度,病变的大小,和手术部位,对72例患者(ERS=24,ORS=48)进行分析。接受ERS的患者手术时间更长(164.25±18.46vs.112.85±14.26分钟;P<0.001),估计失血较少(5.42±2.15vs.18.04±1.62ml;P<0.001),住院时间中位数较短(4.50[3.00-5.00]vs.6.00[5.00-6.00]天;P<0.001)。随访时间ERS组为8.04±1.23个月,ORS组为8.56±1.57个月。对于美学结果,ERS的总体SCAR评分中位数低于ORS(2[1-3]vs.5[4-5];P<0.001),和“疤痕扩散”的分量表,“\”色素沉着,“\”轨迹标记或缝合标记,“”和“总体印象”更好。NRS评分中位数较高(8[7-8]vs.6[5-6];P<0.001),疤痕长度较短(2.18±0.30vs.ERS组8.75±1.98cm;P<0.001)高于ORS组。两组总并发症发生率及复发率比较差异无统计学意义。
    结论:内镜手术是一种安全有效的选择,适用于四肢和躯干的小儿VA。它提供了改善美学结果和减少术后伤口愈合时间的优点。
    BACKGROUND: Endoscopic resection has been reported for vascular anomalies (VA) previously. However, there is no study comparing endoscopic resection surgery (ERS) with open resection surgery (ORS) in children. We aimed to compare clinical and cosmetic outcomes between two approaches in pediatric VA.
    METHODS: Between June 2018 and June 2023, 138 pediatric VA patients undergoing ERS or ORS were retrospectively reviewed. Propensity score matching (PSM) was performed to minimize selection bias. The Scar Cosmesis Assessment and Rating (SCAR) Scale and numerical rating scale (NRS) based on patient satisfaction were used for cosmetic assessment.
    RESULTS: After PSM for age, depth of lesion, size of lesion, and site of surgery, 72 patients (ERS = 24, ORS = 48) were analyzed. Patients undergoing ERS had longer operative time (164.25 ± 18.46 vs. 112.85 ± 14.26 min; P < 0.001), less estimated blood loss (5.42 ± 2.15 vs. 18.04 ± 1.62 ml; P < 0.001), and shorter median hospital stay (4.50 [3.00-5.00] vs. 6.00 [5.00-6.00] days; P < 0.001). The follow-up time was 8.04 ± 1.23 month for ERS group and 8.56 ± 1.57 month for ORS group. For aesthetic results, the median overall SCAR score in ERS was lower than that in ORS (2 [1-3] vs. 5 [4-5]; P < 0.001), and the subscales of \"scar spread,\" \"dyspigmentation,\" \"track marks or suture marks,\" and \"overall impression\" were better. The median NRS score was higher (8 [7-8] vs. 6 [5-6]; P < 0.001) and length of scars was shorter (2.18 ± 0.30 vs. 8.75 ± 1.98 cm; P < 0.001) in ERS group than those in ORS group. The incidences of total complications and recurrence showed no significant difference between two groups.
    CONCLUSIONS: Endoscopic surgery can be a safe and effective option for pediatric VA in the limbs and trunk. It offers the advantages of improving aesthetic outcomes and reducing postoperative wound healing time.
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  • 文章类型: Journal Article
    背景:由于缺乏大样本的循证医学研究,直肠神经内分泌肿瘤根治术的手术方式仍存在争议.
    方法:我们回顾性收集了2010年1月1日至2022年4月30日在中国17家大型三级医院接受根治性切除术的直肠神经内分泌肿瘤患者的病历。将所有患者分为腹腔镜组和开腹手术组。在倾向得分匹配以减少混杂因素之后,比较了两组的术后和肿瘤结局.
    结果:我们招募了174例接受根治性手术的直肠神经内分泌肿瘤患者。随机匹配后,124例患者归入对比(62例,腹腔镜手术组;62例,开腹手术组)。腹腔镜手术组并发症较少(14.5%vs.35.5%,P=0.007)和优越的无复发生存率(P=0.048)。亚组分析显示,腹腔镜手术组并发症较少(10.9%vs.34.7%,P=0.004),术后住院时间较短(9.56±5.21天vs.12.31±8.61天,P=0.049)和直肠神经内分泌肿瘤≤4cm亚组的无复发生存率(P=0.025)。
    结论:腹腔镜手术治疗直肠神经内分泌肿瘤≤4cm患者,可改善术后预后,可作为一种安全可行的直肠神经内分泌肿瘤根治术选择。
    BACKGROUND: Owing to the lack of evidence-based medical studies with large sample sizes, the surgical approach for the radical resection of rectal neuroendocrine tumors remains controversial.
    METHODS: We retrospectively collected the medical records of patients with rectal neuroendocrine tumors who underwent radical resection at 17 large tertiary care hospitals in China between January 1, 2010, and April 30, 2022. All patients were divided into laparoscopic and open surgery groups. After propensity score matching to reduce confounders, the postoperative and oncologic outcomes were compared between the groups.
    RESULTS: We enrolled 174 patients with rectal neuroendocrine tumors who underwent radical surgery. After random matching, 124 patients were included in the comparison (62, laparoscopic surgery group; 62, open surgery group). The laparoscopic surgery group had fewer complications (14.5% vs. 35.5%, P = 0.007) and superior relapse-free survival (P = 0.048). Subgroup analysis revealed that the laparoscopic surgery group had fewer complications (10.9% vs. 34.7%, P = 0.004), shorter postoperative hospital stays (9.56 ± 5.21 days vs. 12.31 ± 8.61 days, P = 0.049) and superior relapse-free survival (P = 0.025) in the rectal neuroendocrine tumors ≤ 4 cm subgroup.
    CONCLUSIONS: Laparoscopic surgery was associated with improved postoperative outcomes and oncologic prognosis for patients with rectal neuroendocrine tumors ≤ 4 cm; it can serve as a safe and feasible option for radical surgery of rectal neuroendocrine tumors.
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  • 文章类型: Journal Article
    背景:微创肺切除术与改善预后相关;然而,与利用相关的制度特征尚不清楚。我们假设机构中手术机器人的存在与微创技术的使用增加有关。
    方法:在国家癌症数据库中确定了2010年至2020年期间接受肺叶切除术的cT1/2N0M0非小细胞肺癌患者。通过手术方法将患者分为微创手术(MIS)和开放手术。如果机构在管理信息系统中的比例>50%,则被归类为MIS技术的“高利用率”。多变量逻辑回归用于确定与微创手术比例相关的因素。使用进一步的多变量模型来评估MIS程序的比例与90天死亡率的关联。住院时间,再入院。
    结果:在多变量分析中,按年划分的时间(比值比[OR]1.26;置信区间[CI]1.22-1.30)和设施中机器人的存在(OR3.48;CI2.84-4.24)与高MIS利用设施相关.MIS的高使用率与90天死亡率(OR0.89;CI0.83-0.97)和住院时间(coeff-0.88;CI-1.03至-0.72)较低相关。高MIS利用设施和低MIS利用设施之间的再入院相似(与低MIS利用设施相比:OR1.06;CI0.95-1.09)。
    结论:时间的流逝和手术机器人的存在与MIS肺叶切除术的利用率增加独立相关。除了与改善患者水平的结果相关外,机器人手术与较高比例的手术是微创执行相关。
    BACKGROUND: Minimally invasive lung resection has been associated with improved outcomes; however, institutional characteristics associated with utilization are unclear. We hypothesized that the presence of surgical robots at institutions would be associated with increased utilization of minimally invasive techniques .
    METHODS: Patients with cT1/2N0M0 non-small cell lung cancer who underwent lung lobectomy between 2010 and 2020 in the National Cancer Database were identified. Patients were categorized by operative approach as minimally invasive surgery (MIS) versus open. Institutions were categorized as \"high utilizers\" of MIS technique if their proportion of MIS lobectomies was >50%. Multivariate logistic regressions were used to determine factors associated with proportion of procedures performed minimally invasively. Further multivariate models were used to evaluate the association of proportion of MIS procedures with 90-d mortality, hospital length of stay, and hospital readmission.
    RESULTS: In multivariate analysis, passage of time by year (odds ratio [OR] 1.26; confidence interval [CI] 1.22-1.30) and presence of a robot at the facility (OR 3.48; CI 2.84-4.24) were associated with high MIS-utilizing facilities. High utilizers of MIS were associated with lower 90-d mortality (OR 0.89; CI 0.83-0.97) and hospital length of stay (coeff -0.88; CI -1.03 to -0.72). Hospital readmission was similar between high and low MIS-utilizing facilities (compared to low MIS-utilizing facilities: OR 1.06; CI 0.95-1.09).
    CONCLUSIONS: Passage of time and the presence of surgical robots were independently associated with increased utilization of MIS lobectomy. In addition to being associated with improved patient-level outcomes, robotic surgery is correlated with a higher proportion of procedures being performed minimally invasively.
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  • 文章类型: Journal Article
    开胸手术已成为支气管囊肿(BC)患者的传统手术方法。本研究旨在评估视频辅助胸腔镜手术(VATS)与开放式手术治疗成人BCs的安全性和有效性。
    这个单一机构,回顾性队列研究纳入了在2019年2月至2023年1月期间接受VATS(A组)或开放手术(B组)的117例接受BC切除术的连续成年患者.有关临床病史的数据,操作持续时间,住院时间,30天死亡率,收集并分析随访期间的复发情况。
    在总队列中,103例(88.0%)患者接受VATS,14例(12.0%)患者接受了开放手术。B组患者年龄明显大于A组(P=0.014),两组间其他人口统计学和基线临床特征无显著差异.VATS组的中位手术时间较短(96vs.149.5分钟,P<0.001)和较短的平均住院时间(5.0±5.5vs.8.6±4.0天,P<0.001)。开放手术组1例死亡。在中位随访34次(四分位距,20.8-42.5)个月,两组均未出现BC复发.
    与开放手术相比,VATS也是治疗成人BCs的安全有效方法。更重要的是,VATS提供了更短的手术时间和住院时间。考虑到微创,VATS可能是大多数支气管囊肿患者的更好选择。
    UNASSIGNED: Open thoracotomy has been the traditional surgical approach for patients with bronchogenic cysts (BCs). This study aimed to evaluate the safety and efficacy of video-assisted thoracoscopic surgery (VATS) compared to open surgery for the treatment of BCs in adults.
    UNASSIGNED: This single-institution, retrospective cohort study included 117 consecutive adult patients who underwent VATS (group A) or open surgery (group B) for BC resection between February 2019 and January 2023. Data regarding clinical history, operation duration, length of hospital stay, 30-day mortality, and recurrence during follow-up were collected and analyzed.
    UNASSIGNED: Of the total cohort, 103 (88.0%) patients underwent VATS, while 14 (12.0%) patients underwent open surgery. Patients\' age in group B were much older than group A (P=0.014), and no significant differences in other demographic and baseline clinical characteristics were observed between the groups. The VATS group had shorter median operation duration (96 vs. 149.5 min, P<0.001) and shorter mean length of hospital stay (5.0±5.5 vs. 8.6±4.0 days, P<0.001). One death occurred in the open surgery group. During a median follow-up of 34 (interquartile range, 20.8-42.5) months, no instances of BC recurrence were observed in either group.
    UNASSIGNED: Compared to open surgery, VATS is also a safe and efficacious approach for treating BCs in adults. What\'s more, VATS offered shorter operative times and hospital stays. Considering the minimally invasive, VATS may be a better choice in most patients with bronchial cysts.
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  • 文章类型: Journal Article
    目标:用于较高级后外侧角(PLC)损伤的关节镜重建技术(FanelliB型,PoLISLI-B)尚未在临床研究中得到验证。Arciero描述的开放式重建技术已得到完善,并且在先前的研究中显示出关节稳定性的良好恢复。这项研究旨在在一项前瞻性随机临床试验中将这种已建立的开放手术技术与新开发的关节镜技术的临床结果进行比较。
    方法:在2019年至2021年之间,这项研究的重点是慢性高级别PLC损伤(FanelliB型,PoLISLI-B)。A组包括采用Arciero技术进行常规开放手术治疗的患者,而B组包括接受Arciero关节镜技术治疗的患者。所有病例均接受了额外的PCL重建。经过至少12个月的随访,比较两组间的临床评分和客观稳定性评估.
    结果:总计,在本研究中评估了26例(A组12,B组14)符合条件的患者,平均随访时间为14.9±7.2个月。当比较术前和术后值时,膝关节稳定性和患者报告的结果评分(PROMS)显着改善(p<0.0001)。PROMS没有临床相关差异(Lysholm:A83.9±11.4与B85.3±13.8;IKDC:A76.91±12.6vs.两组均显示B76.8±15.7)。此外,在外部旋转方面,组间没有发现统计学上的显著差异,运动范围和仪器稳定性测试。关节镜重建显示手术时间明显缩短(p=0.0109)。手术没有临床失败或神经血管并发症。
    结论:两种手术技术治疗孤立性慢性PLCFanelliB型损伤可显著改善膝关节稳定性,与PROM相当,并导致良好的临床结果。然而,与开放式PLC重建相比,关节镜下PLC重建手术时间更短.因此,在有经验的外科医生手中,关节镜PLC重建可能是一个可行的选择。
    方法:前瞻性队列研究,II.
    OBJECTIVE: Arthroscopic reconstruction techniques for higher-grade posterolateral corner (PLC) injuries (Fanelli Type B, PoLIS LI-B) have not yet been validated in clinical studies. The open reconstruction technique described by Arciero is well-established and showed good restoration of joint stability in previous studies. This study aimed to compare clinical outcomes of this established open surgery technique to a newly developed arthroscopic technique in a prospective randomized clinical trial.
    METHODS: Between 2019 and 2021, this study focused on chronic high-grade PLC injuries (Fanelli Type B, PoLIS LI-B). Group A consisted of patients treated with conventional open surgery following Arciero\'s technique, while Group B included patients treated with Arciero\'s arthroscopic technique. All cases underwent additional PCL reconstruction. After a minimum 12-month follow-up, clinical scores and objective stability assessments were compared between the groups.
    RESULTS: In total, 26 (group A 12, group B 14) eligible patients with a mean follow-up of 14.9 ± 7.2 months were evaluated in the present study. Knee stability and patient-reported outcome scores (PROMS) were significantly improved when comparing pre- and post-operative values (p < 0.0001). No clinically relevant differences in PROMS (Lysholm: A 83.9 ± 11.4 vs. B 85.3 ± 13.8; IKDC: A 76.91 ± 12.6 vs. B 76.8 ± 15.7) were shown in both groups. Additionally, no statistically significant differences were detected between groups with respect to external rotation, range of motion and instrumental stability testing. Arthroscopic reconstruction showed significantly shorter operation time (p = 0.0109). There were no clinical failures or neurovascular complications of the surgical procedures.
    CONCLUSIONS: Both surgical techniques for isolated chronic PLC Fanelli Type B injuries significantly improved the knee stability, were equivalent with respect to PROMs and led to good clinical results. However, arthroscopic PLC reconstruction was associated with a shorter surgery time compared to open PLC reconstruction. Therefore, arthroscopic PLC reconstruction may be a viable option in the hands of an experienced surgeon.
    METHODS: Prospective cohort study, II.
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  • 文章类型: Journal Article
    当前的研究旨在评估机器人辅助胸腔镜手术(RATS)对最小直径≥6cm的较大纵隔肿块的安全性和有效性。与电视胸腔镜手术(VATS)和开放手术进行比较。本研究纳入中南医院130例直径不小于6cm纵隔肿瘤患者,武汉大学,包括33名接受了大鼠的患者,52例接受VATS的患者和45例接受开放手术的患者。根据质量大小和是否侵入进行分类后,我们比较了他们的临床特征和围手术期结局.在年龄上没有显著差异,性别,质量大小,重症肌无力,质量位置,3组病理类型(p>0.05)。接受开放手术的患者通常表现为更晚期(p<0.05)。术后平均住院时间无明显差异,操作持续时间,RATS组和VATS组的胸管持续时间和术后第1天平均引流量(p>0.05),RATS组的术中出血量明显低于VATS组(p=0.046)。此外,术后住院时间,操作持续时间,RATS组的胸管持续时间和术中出血量明显低于开放手术组(p<0.001)。RATS是一种在术后早期清除纵隔大肿块的安全有效的方法。与VATS相比,大鼠与较低的术中失血有关。与开放手术相比,大鼠术后住院时间也较短,操作持续时间,胸管持续时间和术中失血。
    Current study aims to assess the safety and efficacy of robot-assisted thoracoscopic surgery (RATS) for sizable mediastinal masses with a minimum diameter ≥6 cm, compared with video-assisted thoracoscopic surgery (VATS) and open surgery. This study enrolled 130 patients with mediastinal tumors with no less than 6 cm diameter in Zhongnan Hospital, Wuhan University, including 33 patients who underwent RATS, 52 patients who underwent VATS and 45 patients who underwent open surgery. After classifying based on mass size and whether it has invaded or not, we compared their clinical characteristics and perioperative outcomes. There was no significant difference in age, gender, mass size, myasthenia gravis, mass location, pathological types (p > 0.05) in three groups. Patients undergoing open surgery typically presenting at a more advanced stage (p < 0.05). No obvious difference was discovered in the average postoperative length of stay, operation duration, chest tube duration and average postoperative day 1 drainage output between RATS group and VATS group (p > 0.05), while intraoperative blood loss in RATS group was significantly lower than VATS group (p = 0.046). Moreover, the postoperative length of stay, operation duration, chest tube duration and intraoperative blood loss in RATS group were significantly lower than open surgery group (p < 0.001). RATS is a secure and efficient approach for removing large mediastinal masses at early postoperative period. In comparison with VATS, RATS is associated with lower intraoperative blood loss. Compared with open surgery, RATS is also associated with shorter postoperative length of stay, operation duration, chest tube duration and intraoperative blood loss.
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  • 文章类型: Journal Article
    淋巴结转移是阴茎癌(PeCa)的主要生存和预后因素。因此,准确分期,预后,和治疗选择需要足够的腹股沟淋巴结清扫术(ILND)。ILND手术应平衡肿瘤的严密性与发病率和术后并发症。我们的目的是比较开放式ILND(OILND)和视频内窥镜ILND(VEILND)在PeCa患者中的可行性和安全性。
    我们在2019年10月至2023年4月之间进行了一项单中心随机试验,采用患者内设计。纳入接受PECA分期或根治性ILND的患者,并随机接受一侧的OILND或VEILND,然后在对侧使用另一种技术。该试验得到当地伦理委员会的批准,并在ClinicalTrials.gov(NCT05887921)上注册。主要结果是VEILND的安全性。次要结果包括两种手术的术中和术后发病率和手术结果,以及根据生存估计的肿瘤学结果。
    我们纳入了14名患者的研究。中位随访时间为12个月(四分位距[IQR]12-17)。OILND和VEILND在手术时间和淋巴结清除数上没有显着差异。然而,VEILND组排水去除的中位时间显著缩短(15d,IQR13-17,95%置信区间[CI]12-17)比OILND组(27d,IQR20-41,95%CI24-31;p=0.025)。术中无并发症,但术后并发症3例(21.4%,95%CI8.4-37.8%)在VEILND组和八个(57.1%,油组的95%CI18.6-54.3%)(p=0.032)。
    VEILND代表了一种安全的技术,可以考虑对PeCa进行分期或治愈,并且在发病率方面似乎比OILND具有优势。需要进一步的高能研究来证实这些初步结果。
    我们比较了两种不同的手术技术切除阴茎癌患者淋巴结的结果。我们发现,视频辅助的锁孔手术方法似乎比开放手术后的并发症发生率更低。
    UNASSIGNED: Nodal metastasis is a major survival and prognostic factor in penile cancer (PeCa). Thus, accurate staging, prognosis, and treatment selection require adequate inguinal lymphadenectomy (ILND). ILND surgery should balance oncologic rigor with morbidity and postoperative complications. Our aim was to compare the feasibility and safety of open ILND (OILND) and videoendoscopic ILND (VEILND) in patients with PeCa.
    UNASSIGNED: We conducted a single-center randomized trial with a within-patient design between October 2019 and April 2023. Patients who were undergoing either staging or radical ILND for PeCa were included and randomized to receive either OILND or VEILND on one side, with the other technique then used on the contralateral side. The trial was approved by the local ethics committee and was registered on ClinicalTrials.gov (NCT05887921). The primary outcome was the safety of VEILND. Secondary outcomes included intraoperative and postoperative morbidity rates and surgical outcomes for the two procedures, as well as oncological outcomes according to survival estimates.
    UNASSIGNED: We included 14 patients in the study. Median follow-up was 12 mo (interquartile range [IQR] 12-17). There were no significant differences in operative time and the number of lymph nodes removed between OILND and VEILND. However, the median time to drain removal was significantly shorter in the VEILND group (15 d, IQR 13-17, 95% confidence interval [CI] 12-17) than in the OILND group (27 d, IQR 20-41, 95% CI 24-31; p = 0.025). No intraoperative complications were observed, but postoperative complications occurred in three cases (21.4%, 95% CI 8.4-37.8%) in the VEILND group and eight (57.1%, 95% CI 18.6-54.3%) in the OILND group (p = 0.032).
    UNASSIGNED: VEILND represents a safe technique to consider for either staging or curative intent in PeCa and seems to have an advantage over OILND in terms of morbidity. Further high-powered studies are warranted to confirm these preliminary results.
    UNASSIGNED: We compared the outcomes of two different surgical techniques to remove lymph nodes in patients with penile cancer. We found that a video-assisted keyhole surgery approach seems to result in a lower rate of complications than after open surgery.
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  • 文章类型: Journal Article
    很少有研究比较机器人辅助的功效,腹腔镜,子宫内膜癌的开放性手术.当考虑机器人手术在日本的位置时,有必要确定它是否有效。我们旨在比较这三种类型的手术治疗早期子宫内膜癌的疗效和安全性。总的来说,175例术前IA期子宫内膜癌患者,接受过剖腹手术的人(n=80),腹腔镜(n=40),或机器人辅助(n=55)在我院2010年至2022年的改良根治性子宫切除术,包括手术结果,围手术期并发症,和预后进行了比较。评估了接受或未接受盆腔淋巴结清扫术的患者之间机器人辅助手术的总手术时间和控制台时间。机器人辅助组的总手术时间最短。腹腔镜和机器人辅助组的估计失血量低于剖腹手术组。在晚期术后IA期病例中,三组的无进展生存期和总生存期无差异.在机器人辅助组中,手术时间随着手术次数的增加而减少;在有和没有进行盆腔淋巴结清扫术的患者中,均有10例达到学习曲线。Clavien-Dindo分级为1级或更高的围手术期并发症的频率在机器人辅助组中最低(p=0.02)。在机器人辅助组中没有Clavien-Dindo分类2级或更高的并发症。机器人辅助手术治疗IA期子宫内膜癌,微创手术,与日本单一机构的腹腔镜和开腹手术相比,手术时间和并发症更少。
    Few studies have compared the efficacy of robot-assisted, laparoscopic, and open surgeries for endometrial cancer. When considering the position of robotic surgery in Japan, it was necessary to determine whether it was effective or not. We aimed to compare the efficacy and safety of these three types of surgeries for early-stage endometrial cancer. In total, 175 patients with endometrial cancer of preoperative stage IA, who had undergone laparotomic (n = 80), laparoscopic (n = 40), or robot-assisted (n = 55) modified radical hysterectomy at our hospital from 2010 to 2022, were included; surgical outcomes, perioperative complications, and prognoses were compared. Total operative and console times for robot-assisted surgery between patients who did or did not undergo pelvic lymphadenectomy were assessed. The robot-assisted group had the shortest total operative time. The estimated blood loss was lower in the laparoscopic and robot-assisted groups than in the laparotomy group. In advanced postoperative stage IA cases, there were no differences in progression-free and overall survival among the three groups. In the robot-assisted group, the operative time decreased as the number of operations increased; the learning curve was reached after 10 cases each of patients with and without pelvic lymphadenectomy. The frequency of perioperative complications of Clavien-Dindo classification Grade 1 or higher was the lowest in the robot-assisted group (p = 0.02). There were no complications of Clavien-Dindo classification Grade 2 or higher in the robot-assisted group. Robot-assisted surgery for stage IA endometrial cancer, a minimally invasive procedure, has fewer operative times and complications than those of laparoscopic and open surgeries in a single institution in Japan.
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  • 文章类型: Journal Article
    在引入筛查后,西方人群的腹主动脉瘤(AAA)流行病学发生了重大变化,血管内AAA修复,减少烟草消费。我们报告了1996年至2018年丹麦AAA修复的发生率和死亡率,其中AAA筛查没有实施。
    来自1996年至2018年基于人口的丹麦登记处的前瞻性数据的全国队列研究。我们使用丹麦血管登记处确定了15,395例首次接受AAA修复的患者。合并症采用Charlson的合并症指数(CCI)进行评估。通过多变量泊松和Cox回归估计发病率(IR)和死亡率(MRR),分别。
    从1996年到2018年,整体AAA修复IR下降了24%,主要反映了男性AAA破裂修复的IR降低了53%。总的来说,70岁以下年龄组的IR降低52-63%,八十岁年龄组的IR升高81%.血管内完整AAAs修复的比例从1996-1999年的2%增加到2015-2018年的42%。对于破裂和完整的AAAs,CCI评分每年增加0.9%,与年龄和性别无关。2016-2018年与1996-2000年的调整后五年MRR在破裂后为0.46(95%置信区间(CI):0.39-0.54),在完整的AAA修复后为0.51(95%CI:0.44-0.59)。
    在丹麦,在1996年至2018年期间,AAA修复的总体发病率有所下降,这主要反映了男性发病率的下降和需要干预的老年人口的转移.这些趋势反映了丹麦烟草消费的变化。不管年龄和合并症,研究期间AAA修复死亡率显著下降。
    UNASSIGNED: Significant changes in Western populations\' abdominal aortic aneurysm (AAA) epidemiology have been reported following the introduction of screening, endovascular AAA repair, and reduced tobacco consumption. We report incidence and mortality of AAA repair in Denmark from 1996 to 2018, where AAA screening was not implemented.
    UNASSIGNED: Nationwide cohort study of prospective data from population-based Danish registries covering 1996 to 2018. We identified 15,395 patients undergoing first-time AAA repair using the Danish Vascular Registry. Comorbidity was assessed by Charlson\'s Comorbidity Index (CCI). Incidence rate (IR) ratios and mortality rate ratios (MRR) were estimated by multivariable Poisson and Cox regression, respectively.
    UNASSIGNED: Overall AAA repair IR decreased by 24% from 1996 through 2018, mainly reflecting a 53% IR reduction in ruptured AAA repairs in men. Overall, the IR decreased 52-63% in age groups below 70 years and increased 81% among octogenarians. The proportion of intact AAAs repaired endovascularly increased from 2% in 1996-1999 to 42% in 2015-2018. For both ruptured and intact AAAs the CCI score increased by 0.9% annually independently of age and sex. The adjusted five-year MRR in 2016-2018 vs.1996-2000 was 0.46 (95% confidence interval (CI): 0.39-0.54) following ruptured and 0.51 (95% CI: 0.44-0.59) following intact AAA repair.
    UNASSIGNED: In Denmark, overall AAA repair incidence decreased between 1996 and 2018, primarily reflecting a reduction among males and a shift to an older population requiring intervention. These trends mirror changes in tobacco consumption in Denmark. Regardless of age and comorbidity, AAA repair mortality decreased markedly during the study period.
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  • 文章类型: Journal Article
    小儿耳鼻喉科手术是至关重要的干预措施,需要仔细考虑手术方法以优化结果。在这种情况下,开放和微创手术方法之间的选择值得彻底研究。虽然这两种方法都旨在解决耳朵问题,鼻子,儿童的喉咙状况,一项比较研究,评估它们对术中参数等关键因素的影响,伤口愈合,并发症,术后疼痛至关重要。本研究旨在比较开放和微创手术方法对小儿耳鼻咽喉科手术伤口愈合和感染的影响。为手术方式的选择提供科学依据。选取两组患者,每组90人。一组接受开放手术,另一组接受微创手术。记录术中时间,麻醉时间,术中出血量;创面愈合所需天数;创面相关并发症发生情况;术后第1、3、7天疼痛情况比较;影响术后创面愈合的因素。在微创手术组中,术中时间较短,麻醉时间相对减少,出血量明显减少。伤口愈合的天数也更少,伤口相关并发症的发生率也更低。当比较手术后1、3和7天的疼痛时,微创手术组疼痛相对较轻。术后伤口愈合因素分析显示微创手术方式对愈合有积极影响。在小儿耳鼻咽喉科手术中,微创手术在术中手术时间方面优于开放手术,麻醉时间,失血,伤口愈合时间,并发症发生率,和术后疼痛。因此,微创手术可能是一种更安全、更有效的手术方法。
    Pediatric otolaryngology surgeries are crucial interventions requiring careful consideration of surgical methods to optimize outcomes. The choice between open and minimally invasive surgical approaches in this context warrants thorough investigation. While both methods aim to address ear, nose, and throat conditions in children, a comparative study assessing their impact on crucial factors such as intraoperative parameters, wound healing, complications, and postoperative pain is essential. This study aims to compare the effects of open and minimally invasive surgical methods on wound healing and infection in pediatric otolaryngology surgery, and provide a scientific basis for the selection of surgical methods. Two groups of patients were selected, with 90 people in each group. One group received open surgery and the other received minimally invasive surgery. Recording the intraoperative time, anesthesia time, and intraoperative blood loss; the number of days required for wound healing; the occurrence of wound-related complications; the comparison of pain on postoperative Days 1, 3, and 7; and the factors influencing postoperative wound healing were analyzed. In the minimally invasive surgery group, the intraoperative time was shorter, the anesthesia time was relatively reduced, and the amount of bleeding was significantly reduced. Wounds also take fewer days to heal and have lower rates of wound-related complications. When comparing the pain on 1, 3, and 7 days after surgery, the minimally invasive surgery group had relatively mild pain. Analysis of postoperative wound healing factors showed that minimally invasive surgical methods have a positive impact on healing. In pediatric otolaryngology surgery, minimally invasive surgery performs better than open surgery in terms of intraoperative operation time, anesthesia time, blood loss, wound healing time, complication rate, and postoperative pain. Therefore, minimally invasive surgery may be a safer and more effective surgical method.
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