目的:肥胖是一个涉及大量人群的世界性问题。由于一些饮食因素可能通过各种信号通路改变肥胖,这项研究的目的是调查合生元加维生素D共同补充对身体成分参数和生活质量的影响,中年超重和肥胖女性。
方法:随机,控制,进行了双盲试验,将88名超重和肥胖妇女分为4组(每组22名),接受合生元和维生素D,合生元,维生素D和安慰剂8周。在审判开始和结束时,人体测量指数,身体成分指标,身体活动水平,饮食摄入量,和生活质量评分由训练有素的营养学家测量。使用SPSS版本22进行统计学分析。
结果:结果显示4组腰围(WC)之间存在显着差异,脂肪量(FM),治疗8周后的体脂百分比(BFP)和内脏脂肪面积(VFA)值(分别为P=0.005,P=0.007,P=0.003和P=0.009),与安慰剂相比,合生元加维生素D组的降幅最大。在其他身体成分变量方面,组间没有显着结果。此外,在身体方面,4组之间没有显着差异,随着时间的推移,生活质量的精神和总体方面。
结论:我们的研究表明,合元和维生素D共同补充8周,对各种人体测量指标和身体成分指标有良好的影响,但生活质量评分没有理想的变化。
背景:IRCT(注册号:IRCT20090822002365N25)。
Obesity is a worldwide problem which has involved large populations. Since some dietary factors might modify obesity through various signaling pathways, the aim of this
study was to investigate the effect of synbiotic plus vitamin D co-supplementation on body composition parameters and quality of life, in middle-aged overweight and obese women.
A randomized, controlled, double-blinded
trial was performed and 88 overweight and obese women were assigned to 4 groups (22 per group), receiving synbiotic plus vitamin D, synbiotic, vitamin D and placebo for 8 weeks. At the beginning and at the end of the
trial, anthropometric indices, body composition indicators, physical activity level, dietary intake, and quality of life score were measured by trained nutritionists. Statistical analysis was performed with SPSS version 22.
The results showed significant difference between 4 groups in waist circumference (WC), fat mass (FM), body fat percentage (BFP) and visceral fat area (VFA) values after 8 weeks of treatment (P = 0.005, P = 0.007, P = 0.003, and P = 0.009, respectively), with the greatest reduction in synbiotic plus vitamin D group compare to placebo. No significant results were demonstrated between groups in relation to other body composition variables. In addition, there were no significant differences between the 4 groups regarding physical, mental and total aspects of life quality over time.
Our
study demonstrated that synbiotic and vitamin D co-supplementation for 8 weeks, had favorable effect on various anthropometric indices and body composition indicators, but no desirable change in life quality score.
IRCT (registration no. IRCT20090822002365N25).