Abstract：
Background: This study aims to investigate the prevalence of possible sarcopenia and its associated factors among middle-aged Vietnamese women. Methods: A cross-sectional study was conducted on 205 women aged 40-55 years who were admitted to the Can Tho Obstetrics and Gynecology Hospital between February and December 2023. The presence of possible sarcopenia was determined according to the AWGS 2019 criteria. Associated factors were dietary intake (total energy, protein, lipid, and carbohydrate intake), the severity of menopausal symptoms by using the Kupperman index, and body composition by using the bioelectrical impedance analysis device, Inbody S10. Logistic regressions were built to analyze the association between possible sarcopenia and its associated factors. Results: The prevalence of possible sarcopenia was 29.8%, with a mean age of 47.2. Possible sarcopenia was detected in 23% of the participants based on the criterion of low handgrip strength, whereas 83.6% of the participants when considered low performance in the chair stand test. Adjusted logistic regression analysis showed that living in a rural area (adjusted odds ratio [AOR]: 2.16, 95% confidence interval [95% CI]: 1.22-4.72), energy intake <25 kcal/body weight, (AOR: 1.94, 95% CI: 1.75-5.06), protein intake <0.91 g/body weight (AOR: 2.42, 95% CI: 1.51-5.76), skipping breakfast (AOR: 2.03, 95% CI: 0.91-4.54), mild menopausal symptoms (AOR: 2.68, 95% CI: 1.61-5.36), and obesity (AOR: 1.59, 95%CI: 1.29-3.67) were significantly associated with higher risk of possible sarcopenia. Conversely, higher muscle mass and higher upper limb mass were associated with a decreased risk of possible sarcopenia (total muscle mass AOR: 0.20, 95% CI: 0.07-0.59). Conclusions: These findings would provide a basis for enhancing management and prevention strategies to reduce the risk of sarcopenia in Vietnam. In particular, attention to nutrient intake and the management of menopausal symptoms may reduce the risk of sarcopenia.
摘要：
背景：本研究旨在调查越南中年女性中可能的肌肉减少症的患病率及其相关因素。方法：对2023年2月至12月间入住CanTho妇产科医院的205名40-55岁女性进行了横断面研究。根据AWGS2019标准确定可能存在的肌肉减少症。相关因素是饮食摄入(总能量，蛋白质，脂质，和碳水化合物摄入量)，使用Kupperman指数评估更年期症状的严重程度，通过使用生物电阻抗分析装置，InbodyS10。采用Logistic回归分析可能的肌少症与其相关因素之间的关系。结果:可能的肌少症患病率为29.8%,平均年龄47.2岁.根据低握力的标准，在23％的参与者中检测到可能的肌肉减少症，而83.6%的参与者在椅子站立测试时认为性能较低。调整后的逻辑回归分析显示，居住在农村地区（调整后的比值比[AOR]：2.16，95％置信区间[95％CI]：1.22-4.72），能量摄入<25千卡/体重，（AOR：1.94，95%CI：1.75-5.06），蛋白质摄入量<0.91g/体重（AOR：2.42，95％CI：1.51-5.76），不吃早餐(AOR：2.03，95%CI：0.91-4.54)，轻度更年期症状（AOR：2.68，95%CI：1.61-5.36），肥胖(AOR:1.59,95CI:1.29-3.67)与更高的可能的肌少症风险显著相关。相反，较高的肌肉质量和较高的上肢质量与可能的肌肉减少症风险降低相关(总肌肉质量AOR:0.20,95%CI:0.07~0.59).结论：这些发现将为加强管理和预防策略以降低越南少肌症的风险提供依据。特别是,注意营养摄入和更年期症状的管理可能会降低少肌症的风险。
