Abstract：
Aneurysmal bone cyst (ABC) is a benign locally destructive bone neoplasm composed of multi-loculated blood-filled cystic spaces. The most common sites of involvement are the meta-diaphysis of the long bones and posterior elements of the vertebrae. Secondary, ABC-like changes can complicate a variety of other benign and malignant primary bone neoplasms, including giant cell tumor, fibrous dysplasia, and osteosarcoma. About two-third of primary ABCs have a rearrangement of the USP6 gene, which is not present in the ABC-like changes that occur secondary to other primary bone tumors (i.e., secondary ABC). Primary ABC of bone carries a variable but generally high rate of local recurrence. This paper provides an overview of the pathophysiology, clinical presentation, radiographic and pathologic findings, treatment, and prognosis of ABC.
摘要：
动脉瘤性骨囊肿（ABC）是一种良性的局部破坏性骨肿瘤，由多部位充满血液的囊性空间组成。最常见的受累部位是长骨的骨干和椎骨的后部元素。次要,ABC样变化可使多种其他良性和恶性原发性骨肿瘤复杂化，包括巨细胞瘤,纤维发育不良,和骨肉瘤.大约三分之二的初级ABC具有USP6基因的重排，在其他原发性骨肿瘤继发的ABC样变化中不存在(即，二级ABC）。骨的原发性ABC具有可变的但通常较高的局部复发率。本文概述了病理生理学，临床表现,放射学和病理学发现，治疗,和ABC的预后。
