目的:本研究旨在对比和比较血清铁蛋白,血红蛋白,维生素D3,Ca++,促甲状腺激素释放激素(TRH),严重龋齿(SC)学龄前儿童之间的血清白蛋白水平以及控制龋齿的措施。
方法:选择了300名儿童的样本量,但只有266名参与;54.14%的SC和45.86%的无龋。血清铁蛋白的血样,血红蛋白,维生素D3,Ca++,TRH,和血清白蛋白水平。
结果:平均年龄估计为40.82±14.09个月。样本受检者的血清铁蛋白水平估计平均值为29.58±17.87μg/L,而测量的血红蛋白水平平均值为115.13±10.12g/L。Logistic回归分析(LRA)表明,与龋齿控制儿童相比,SC儿童的铁蛋白水平下降的可能性几乎是后者的两倍,并且FeDA(缺铁性贫血)的可能性可能是后者的六倍。SC患儿的平均维生素D3值显着降低(p<0.001),Ca++(p<0.001),和血清白蛋白(p<0.001)水平,促甲状腺激素释放因子(p<0.001)水平明显高于无龋齿的受试者。
结论:对年龄很小的SC患儿的分析显示,与无龋齿的口腔患儿相比,低铁蛋白水平的机会增加。患有SC的儿童在很小的时候血红蛋白水平就不足。与没有龋齿的儿童相比,患有SC的儿童在很小的时候似乎营养不良。其他对比参数,如FeDA,维生素D3,Ca++,和血清白蛋白浓度显着不足SC儿童在很小的时候,相比之下,一个没有龋齿的孩子的样本。分析还表明TRH水平增加。
结论:以下研究为牙科兄弟会和其他健康专家分析血清铁蛋白树立了基准,血红蛋白,维生素D3,Ca++,TRH,和血清白蛋白水平,而一般治疗儿科患者。因此,即使在龋齿中,也应合理地规定补充剂。
■JhaA,JhaS,ShreeR,etal.血清铁蛋白,血红蛋白,维生素D3,血清白蛋白,钙,促甲状腺激素释放激素与早期儿童龋齿的病例对照研究.IntJClinPediatrDent2021;14(5):648-651。
OBJECTIVE: This study aimed to contrast and compare serum ferritin, hemoglobin, Vitamin D3, Ca++, thyrotropin-releasing hormone (TRH), and serum albumin levels between preschoolers with severe caries (SC) and measures taken for caries control.
METHODS: A sample size of 300 children was selected but only 266 participated; 54.14% with SC and 45.86% caries-free. Blood samples for serum ferritin, hemoglobin, Vitamin D3, Ca++, TRH, and serum albumin levels were taken.
RESULTS: The mean age was estimated to be 40.82 + 14.09 months. The serum ferritin level estimated mean value for sample pedodontic subjects came to be 29.58 ± 17.87 μg/L whereas their hemoglobin level with mean value 115.13 ± 10.12 g/L was measured. Logistic regression analysis (LRA) suggested that children with SC were nearly two times as likely to have ferritin level depreciation and likely six times more chance of FeDA (iron deficiency anemia) than in children with caries control. Children with SC had significantly lower mean Vitamin D3 value (p < 0.001), Ca++ (p < 0.001), and serum albumin (p < 0.001) levels, and significantly higher thyrotropin-releasing factor (p < 0.001) levels than those subjects without caries.
CONCLUSIONS: Analysis of children with SC at a very young age significantly showed an increased chance of low ferritin levels than children with a caries-free mouth. The level of hemoglobin was deficient in children with SC at a very young age. Children with SC at a very young age appeared to be malnourished when compared with children without dental caries. Other contrasting parameters like FeDA, Vitamin D3, Ca++, and serum albumin concentrations were significantly deficient in children with SC at a very young age, in contrast, to a sample of children with a caries-free mouth. The analysis also suggested an increased level of TRH.
CONCLUSIONS: The following research study sets a benchmark for the dental fraternity and other health specialists to analyze serum ferritin, hemoglobin, Vitamin D3, Ca++, TRH, and serum albumin levels while generally treating pediatric patients. Accordingly, supplements should be prescribed rationally even in dental caries.
UNASSIGNED: Jha A, Jha S, Shree R, et al. Association between Serum Ferritin, Hemoglobin, Vitamin D3, Serum Albumin, Calcium, Thyrotropin-releasing Hormone with Early Childhood Caries: A
Case-Control Study. Int J Clin Pediatr Dent 2021;14(5):648-651.