Time and Motion Studies

时间与运动研究
  • 文章类型: Journal Article
    基于OpenPose的运动分析(OpenPose-MA),利用深度学习方法,已经成为估计人体运动的一种引人注目的技术。它解决了与传统三维运动分析(3D-MA)和基于人类视觉检测的运动分析(Human-MA)相关的缺点。包括昂贵的设备,耗时的分析,和受限制的实验设置。本研究旨在评估OpenPose-MA与Human-MA的精确度,使用3D-MA作为参考标准。该研究涉及21名年轻健康成年人。OpenPose-MA采用了OpenPose算法,一种基于深度学习的开源二维(2D)姿态估计方法。人-MA由熟练的物理治疗师进行。OpenPose-MA和Human-MA使用相同的额平面视频图像计算了垂直跳跃任务期间的膝盖外翻角度,3D-MA作为参考标准。各种指标被用来评估再现性,不同方法之间膝关节外翻角度的准确性和相似性,包括组内相关系数(ICC)(1,3),平均绝对误差(MAE),波形模式相似性的多重相关系数(CMC),和皮尔逊相关系数(OpenPose-MA与3D-MA,Human-MAvs.3D-MA)。进行非配对t检验以比较OpenPose-MA和Human-MA之间的MAE和CMC。OpenPose-MA的ICC(1,3),Human-MA,和3D-MA在DVJ试验中表现出优异的重现性。就MAE而言,OpenPose-MA和Human-MA之间没有显着差异(OpenPose:2.4°[95CI:1.9-3.0°],人:3.2°[95CI:2.1-4.4°])或CMC(开口姿势:0.83[范围:0.99-0.53],人:0.87[范围:0.24-0.98])的膝关节外翻角度。OpenPose-MA和Human-MA相对于3D-MA的Pearson相关系数分别为0.97和0.98。这项研究表明,OpenPose-MA获得了令人满意的重现性,准确性和表现出与3D-MA相当的波形相似性,类似于人类MA。就膝关节外翻角度偏移而言,OpenPose-MA和Human-MA均与3D-MA具有很强的相关性。
    OpenPose-based motion analysis (OpenPose-MA), utilizing deep learning methods, has emerged as a compelling technique for estimating human motion. It addresses the drawbacks associated with conventional three-dimensional motion analysis (3D-MA) and human visual detection-based motion analysis (Human-MA), including costly equipment, time-consuming analysis, and restricted experimental settings. This study aims to assess the precision of OpenPose-MA in comparison to Human-MA, using 3D-MA as the reference standard. The study involved a cohort of 21 young and healthy adults. OpenPose-MA employed the OpenPose algorithm, a deep learning-based open-source two-dimensional (2D) pose estimation method. Human-MA was conducted by a skilled physiotherapist. The knee valgus angle during a drop vertical jump task was computed by OpenPose-MA and Human-MA using the same frontal-plane video image, with 3D-MA serving as the reference standard. Various metrics were utilized to assess the reproducibility, accuracy and similarity of the knee valgus angle between the different methods, including the intraclass correlation coefficient (ICC) (1, 3), mean absolute error (MAE), coefficient of multiple correlation (CMC) for waveform pattern similarity, and Pearson\'s correlation coefficients (OpenPose-MA vs. 3D-MA, Human-MA vs. 3D-MA). Unpaired t-tests were conducted to compare MAEs and CMCs between OpenPose-MA and Human-MA. The ICCs (1,3) for OpenPose-MA, Human-MA, and 3D-MA demonstrated excellent reproducibility in the DVJ trial. No significant difference between OpenPose-MA and Human-MA was observed in terms of the MAEs (OpenPose: 2.4° [95%CI: 1.9-3.0°], Human: 3.2° [95%CI: 2.1-4.4°]) or CMCs (OpenPose: 0.83 [range: 0.99-0.53], Human: 0.87 [range: 0.24-0.98]) of knee valgus angles. The Pearson\'s correlation coefficients of OpenPose-MA and Human-MA relative to that of 3D-MA were 0.97 and 0.98, respectively. This study demonstrated that OpenPose-MA achieved satisfactory reproducibility, accuracy and exhibited waveform similarity comparable to 3D-MA, similar to Human-MA. Both OpenPose-MA and Human-MA showed a strong correlation with 3D-MA in terms of knee valgus angle excursion.
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  • 文章类型: Journal Article
    目的是确定健康和慢性踝关节不稳定(CAI)参与者的认知约束和神经肌肉疲劳对着陆生物力学的影响。23名男性志愿者(13名对照和10名CAI)在疲劳运动之前和之后立即进行了单腿着陆任务,有或没有认知约束。在垂直着陆时确定地面反作用力(GRF)和稳定时间(TTS),使用力板的前后轴(ap)和中外侧轴(ml)。臀部的三维运动,在着陆时使用动作捕捉系统记录膝盖和脚踝.运动性疲劳可降低踝关节足底屈曲和内翻,并增加膝关节屈曲。神经肌肉疲劳降低了垂直GRF,增加了mlGRF和apTTS。在着陆的飞行阶段,认知约束减少了踝关节内旋,增加了膝盖和臀部的屈曲。认知约束增加了所有三个轴的mlGRF和TTS。因素之间没有相互作用(组,疲劳,认知)被观察到。疲劳和认知约束导致较大的膝关节和髋关节屈曲,在着陆过程中显示出更高的近端控制。踝关节运动学提出了一种针对疲劳和认知约束的保护策略。最后,这两个约束会损害动态稳定性,从而增加踝关节扭伤的风险。
    The purpose was to determine the impact of both cognitive constraint and neuromuscular fatigue on landing biomechanics in healthy and chronic ankle instability (CAI) participants. Twenty-three male volunteers (13 Control and 10 CAI) performed a single-leg landing task before and immediately after a fatiguing exercise with and without cognitive constraints. Ground Reaction Force (GRF) and Time to Stabilization (TTS) were determined at landing in vertical, anteroposterior (ap) and mediolateral (ml) axes using a force plate. Three-dimensional movements of the hip, knee and ankle were recorded during landing using a motion capture system. Exercise-induced fatigue decreased ankle plantar flexion and inversion and increased knee flexion. Neuromuscular fatigue decreased vertical GRF and increased ml GRF and ap TTS. Cognitive constraint decreased ankle internal rotation and increased knee and hip flexion during the flight phase of landing. Cognitive constraint increased ml GRF and TTS in all three axes. No interaction between factors (group, fatigue, cognitive) were observed. Fatigue and cognitive constraint induced greater knee and hip flexion, revealing higher proximal control during landing. Ankle kinematic suggests a protective strategy in response to fatigue and cognitive constraints. Finally, these two constraints impair dynamic stability that could increase the risk of ankle sprain.
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  • 文章类型: Journal Article
    可穿戴设备量化了团队运动中的活动,并表明球员在比赛中遇到了最大的身体负荷。因此,在比赛中上场时间有限的球员将错过重要的训练刺激。本研究旨在量化职业手球运动员身体负荷的这些差距。使用KinexonLPS传感器跟踪所有参加2021/2022德甲(德国)比赛的球员的活动。将25%的外观与最高(高;51.8±5.2分钟)和最低的球场时间(低;10.1±4.3分钟)进行比较,对物理负荷的差距进行了量化。距离,累积加速度,跳跃,冲刺,影响,加速度,和减速分析为绝对和相对(每分钟)结果。玩家被分成翅膀,后场,和枢轴。在HIGH和LOW之间进行非配对t检验(p<0.05),并计算效应大小(科恩d)。分析表明,法庭时间对活动有重大影响。虽然绝对活性增加为高,低的相对活性增加(p<0.05)。此外,效应大小揭示了物理载荷中特定位置的间隙,特别是对于非循环活动(跳跃,加速度)。法庭时间有限导致的物理负荷差距是高度特定于位置的。我们的观察结果可以为补偿训练的位置特定校准提供基准。
    Wearables quantify the activity in team sports and indicate that players experience peak physical loads during competitions. Accordingly, players with limited court time in competitions will miss important training stimuli. The present study aimed to quantify these gaps in physical load in professional handball players. Activity of all players competing in the 2021/2022 Bundesliga (Germany) was tracked using Kinexon LPS sensors. Gaps in physical load were quantified comparing the 25% of appearances with the highest (HIGH; 51.8 ± 5.2 mins) and lowest court times (LOW; 10.1 ± 4.3 mins). Distances, accumulated acceleration, jumps, sprints, impacts, accelerations, and decelerations were analysed as absolute and relative (per minute) outcomes. Players were grouped into wings, backcourts, and pivots. Unpaired t-tests between HIGH and LOW were performed (p < .05), and effect sizes were calculated (Cohen´s d). Analyses revealed significant effects of court time on activity. While absolute activity increased for HIGH, relative activity increased for LOW (p < .05). In addition, effect sizes revealed position-specific gaps in physical load, particularly for acyclic activities (jumps, accelerations). Gaps in physical load resulting from limited court time are highly position-specific. Our observations may provide benchmarks for the position-specific calibration of compensatory training.
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  • 文章类型: Journal Article
    加载外侧和内侧隔室对于了解侧切过程中肌肉疲劳的影响至关重要。本研究调查了特定于手球的疲劳方案后,在切边动作过程中,内侧和外侧隔室的胫骨接触力的变化以及肌肉力量的贡献。二十名女手球运动员在疲劳方案之前(基线)和之后进行了三次切边动作试验。测量了运动捕获力和地面反作用力,并在OpenSim中处理数据。使用统计参数映射(SPM)比较变量,显著性水平为p<0.05。结果表明,在早期站立阶段疲劳期间,膝关节屈曲角度减小。此外,疲劳后分析显示肌肉力量显著降低.同样,在疲劳期间,SPM分析显示,在垂直和向前方向上,胫骨股接触力降低。疲劳方案后,施加到内侧和外侧髁的垂直力显示出显着降低。这些结果表明,与基线值相比,在疲劳方案之后施加到胫股关节的力减小。然而,没有一致的证据表明疲劳会增加膝关节损伤的风险.
    Loading both lateral and medial compartments is crucial to understanding the effect of muscle fatigue during sidestep cutting. The present study investigated the changes in tibiofemoral contact forces in the medial and lateral compartments and the muscle force contributions during the sidestep-cutting manoeuvre after a handball-specific fatigue protocol. Twenty female handball athletes performed three trials of the sidestep-cutting manoeuvre before (baseline) and after the fatigue protocol. Motion capture and ground reaction forces were measured, and the data were processed in OpenSim. The variables were compared using statistical parametric mapping (SPM), with a significance level of p < 0.05. The results showed a decreased knee flexion angle during fatigue in the early stance phase. In addition, the post-fatigue analysis demonstrated significantly reduced forces in vasti muscles. Similarly, during fatigue, the SPM analysis showed decreased tibiofemoral contact forces in the vertical and anterior directions. Vertical force applied to both medial and lateral condyles demonstrated a significant reduction after the fatigue protocol. These results indicated that forces applied to the tibiofemoral joint were reduced following the fatigue protocol compared to the baseline values. However, no consistent evidence exists that fatigue increases the risk of knee injuries.
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  • 文章类型: Journal Article
    最近,已经观察到世界级撑杆跳高运动员行为的各种技术方法。这项研究的目的是使用不同的技术方法调查亚组的存在,并比较生物力学性能差异。根据起飞时顶手的相对位置以及从起飞到最大杆弯曲的杆顶部的方向,使用K均值方法对99名运动员超过5.00米的表现进行了生物力学分析。分析显示了四个亚组,它们通过较高和较低的方向角和相对位置值来区分。尽管技术不同,分析没有发现这四组在表现上有显著差异,起飞速度,或运动员人体测量学。然而,这些集群展示了杆运动员互动和杆弯曲的变化,建议与每种方法相关的不同策略和物理要求。集群2以经典技术为特征,具有高方向角和靠近垂直平面的起飞位置。第4组展示了一种低起飞角度的技术,暗示像Lavillenie这样的运动员的影响,偏离了传统的模式。根据他们喜欢的技术理解和分类运动员可以帮助教练提供量身定制的指导,导致性能改进。
    Recently, a variety of technical approaches in world-class pole-vaulters\' behaviour have been observed. The aim of this study was to investigate the presence of subgroups using different technical approaches and to compare biomechanical performance differences. Biomechanical analysis of performances over 5.00 metres from 99 athletes were clustered with K-means methodology based on the relative position of the top hand at take-off and the direction of the top of the pole from take-off to the maximal pole bending. Analysis revealed four subgroups that were distinguished by higher and lower direction angle and relative position values. Despite differences in technique, the analysis did not reveal significant differences between these four groups in performance, take-off speed, or athlete anthropometrics. Nevertheless, these clusters showcased variations in pole-athlete interactions and pole bending, suggesting different strategies and physical requirements associated with each approach. Cluster 2 characterised the classical technique with a high direction angle and a take-off position close to the vertical plane. Cluster 4 displayed a technique with a low take-off angle, suggesting the influence of athletes like Lavillenie, in deviating from the conventional model. Understanding and categorising athletes based on their preferred technique can aid coaches in providing tailored instructions, leading to performance improvements.
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  • 文章类型: Journal Article
    这项研究使用1、5和10分钟的滚动平均值检查了官方足球比赛中最苛刻的场景(MDS)的频率。42名来自不同位置的19岁以下球员(中后卫,后卫,中央中场,广泛的中场,进攻中场,和前锋)使用GPS跟踪27场比赛的距离,高速运行,冲刺距离,加速度,和减速。强度阈值基于百分位数(0-25、25-50、50-75、75-100和≥100)建立。主要发现表明:(i)峰值需求发生在所有位置的所有时间窗口和变量的不到1%;(ii)大多数努力发生在峰值需求以下,高速运行和冲刺距离约占95%,85%的加速度,减速,和总距离;(iii)发现位置之间的强度分布存在显着差异,特别是在中低和高强度。关于培训处方,仅依靠MDS可能是有限的,强调需要用其他指标来补充MDS,以便全面了解比赛需求。这种方法可以确保为足球运动员提供更明智的培训计划。
    足球比赛期间高峰需求事件的发生很少。因此,了解频率的努力低于强度阈值的最苛刻的通道为每个比赛的位置和跨各种分析的变量和周期是至关重要的。MDS可能不足以进行有效的足球训练计划。补充额外的指标,如GPS,战术分析,生理数据和心理因素对于全面了解游戏需求和量身定制的培训计划至关重要。
    This study examined the frequency of the most demanding scenarios (MDS) during official soccer matches using rolling averages over 1, 5, and 10 min. Forty-two Under-19 players from different positions (central defenders, full-backs, central midfielders, wide midfielders, offensive midfielders, and forwards) were monitored across 27 matches using GPS to track distance covered, high-speed running, sprint distance, accelerations, and decelerations. Intensity thresholds were established based on percentiles (0-25, 25-50, 50-75, 75-100, and ≥100). The main findings suggest that: (i) Peak Demands occur in less than 1% of all time windows and variables for all positions; (ii) Most efforts occur below peak demands, with around 95% for high-speed running and sprint distance, and 85% for accelerations, decelerations, and total distance; (iii) Significant differences in intensity distributions were found between positions, particularly at medium-low and high intensities. Regarding training prescription, relying solely on MDS may be limited, highlighting the need to supplement MDS with other metrics for a comprehensive understanding of match demands. This approach ensures better-informed training programs for soccer players.
    The occurrence of peak demand events during soccer matches is infrequent. Therefore, understanding the frequency of efforts below the intensity threshold of the most demanding passages for each playing position and across various analysed variables and periods is of utmost importance.MDS might not be enough for effective soccer training planning. Complementing with additional metrics like GPS, tactical analysis, physiological data and psychological factors is essential for a comprehensive understanding of the game’s demands and tailored training programmes.
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  • 文章类型: Journal Article
    背景:幼儿龋齿(ECC)是影响数百万儿童的重大全球健康问题。缓解这一问题需要来自可靠的监视系统的最新信息。这使基于证据的决策能够制定口腔健康政策。世界卫生组织(WHO)提倡在口腔疾病监测中采用移动技术,因为它们的效率和易于应用。该研究描述了开发一种电子,埃及学龄前儿童口腔健康监测系统(EOHSS),使用地区卫生信息系统(DHIS2)开源平台及其Android应用程序,并评估其在数据采集中的可行性。
    方法:为DHIS2TrackerAndroidCapture应用程序配置了DHIS2服务器,以允许个人级别的数据输入。根据世卫组织2030年行动计划选择了EOHSS指标。基于临床数据捕获开发了两种用于EOHSS的模式:面对面和远程/异步。试点团队中的八名牙医使用特定于模态的电子设备收集了214个事件。飞行员团队的反馈是关于EOHSS在收集数据方面的可行性,我们进行了时间-运动研究,以评估两周内的工作流程.采用独立t检验和统计过程控制技术进行数据分析。
    结果:试验小组报告了对EOHSS结构的积极反馈。在从儿童获取临床数据之前,通过收集护理人员的数据来调整工作流程以确定监测任务的优先级,以提高工作效率。与远程模拟(5.1±0.9分钟)相比,面对面模式(4.2±0.7分钟)需要更短的数据捕获时间。p<0.001)。临床数据的采集占两种模式所需时间的16.9%和21.1%,分别。面对面模态所需的时间表现出随机变化,远程模态任务显示出执行任务的时间减少的趋势。
    结论:DHIS2为开发电子,口腔健康监测系统。与面对面相比,远程数据的数据捕获时间相差一分钟,这表明尽管耗时略多,远程医疗仍然显示出远程口腔健康评估的希望,这在牙科专业人员有限的地区特别有价值。有可能扩大口腔健康筛查计划的范围。
    BACKGROUND: Early childhood caries (ECC) is a major global health issue affecting millions of children. Mitigating this problem requires up-to-date information from reliable surveillance systems. This enables evidence-based decision-making to devise oral health policies. The World Health Organization (WHO) advocates the adoption of mobile technologies in oral disease surveillance because of their efficiency and ease of application. The study describes developing an electronic, oral health surveillance system (EOHSS) for preschoolers in Egypt, using the District Health Information System (DHIS2) open-source platform along with its Android App, and assesses its feasibility in data acquisition.
    METHODS: The DHIS2 Server was configured for the DHIS2 Tracker Android Capture App to allow individual-level data entry. The EOHSS indicators were selected in line with the WHO Action Plan 2030. Two modalities for the EOHSS were developed based on clinical data capture: face-to-face and tele/asynchronous. Eight dentists in the pilot team collected 214 events using modality-specific electronic devices. The pilot\'s team\'s feedback was obtained regarding the EOHSS\'s feasibility in collecting data, and a time-motion study was conducted to assess workflow over two weeks. Independent t-test and Statistical Process Control techniques were used for data analysis.
    RESULTS: The pilot team reported positive feedback on the structure of the EOHSS. Workflow adaptations were made to prioritize surveillance tasks by collecting data from caregivers before acquiring clinical data from children to improve work efficiency. A shorter data capture time was required during face-to-face modality (4.2 ± 0.7 min) compared to telemodality (5.1 ± 0.9 min), p < 0.001). The acquisition of clinical data accounted for 16.9% and 21.1% of the time needed for both modalities, respectively. The time required by the face-to-face modality showed random variation, and the tele-modality tasks showed a reduced time trend to perform tasks.
    CONCLUSIONS: The DHIS2 provides a feasible solution for developing electronic, oral health surveillance systems. The one-minute difference in data capture time in telemodality compared to face-to-face indicates that despite being slightly more time-consuming, telemodality still shows promise for remote oral health assessments that is particularly valuable in areas with limited access to dental professionals, potentially expanding the reach of oral health screening programs.
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  • 文章类型: Journal Article
    目的:比较2种水下拔出蛙泳技术的运动学特征。
    方法:16名游泳运动员(9名男子,20.67[2.71]岁;7名妇女,18.86[0.83]yold)使用2种抽出式蛙泳技术进行3×25-m蛙泳:Fly-Kickfirstandcombined。使用速度计评估滑行过程中的峰值和平均速度,推进,以及两种技术的恢复阶段,以及整个水下序列。从视频片段中检索水下距离,并考虑每种拔出技术。还恢复了飞踢过程中膝盖的运动范围,完成25米的时间被认为是性能结果,伴随着平均速度,中风率,行程长度,和中风指数。
    结果:速度-时间序列显示出拉出技术之间的不同轮廓(P≤0.05),主要是在男性和女性的滑翔和推进阶段,分别。使用Fly-Kick优先技术时,女性的平均速度为25m(P=.05,d=0.36)。在两个队列中,该技术的水下总距离和膝盖运动范围也都观察到了更大的值。结论:女性游泳者在使用Fly-Kick优先技术时表现出更高的表现。当游泳者使用不同的水下拔出技术时,会出现不同的运动学轮廓,其中Fly-Kick首先可以使他们达到更高的运动学标准。
    OBJECTIVE: To compare the kinematic profile of 2 underwater pullout breaststroke techniques.
    METHODS: Sixteen swimmers (9 men, 20.67 [2.71] y old; 7 women, 18.86 [0.83] y old) performed 3 × 25-m breaststroke using 2 pullout breaststroke techniques: Fly-Kick first and Combined. A speedometer was used to assess the peak and the mean velocity during the glide, propulsion, and recovery phases of both techniques, as well as for the total underwater sequence. The underwater distance was retrieved from video footage and was considered for each pullout technique. The range of motion of the knee during the fly-kick was also retrieved, and the time to complete the 25 m was considered the performance outcome, accompanied by the mean velocity, stroke rate, stroke length, and stroke index.
    RESULTS: Velocity-time series showed different profiles between pullout techniques (P ≤ .05) mostly in the glide and propulsion phases for males and females, respectively. The mean velocity of 25 m was shown to be greater in females when using the Fly-Kick first technique (P = .05, d = 0.36). Greater values in total underwater distance and knee range of motion were also observed for this technique in both cohorts. Conclusions: Female swimmers presented a higher performance when using the Fly-Kick first technique. Different kinematic profiles arise when swimmers use different underwater pullout techniques where the Fly-Kick first may allow them to reach higher kinematical standard.
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  • 文章类型: Journal Article
    目的:本研究旨在通过描述最坏情况(WCS)以及总距离(TD)和高速运行(HSR)超过WCS的80%和90%的时间来增强对足球比赛高峰需求的理解。调查考虑了比赛水平(一线队vs19岁以下[U19]队)和比赛位置(中后卫,后卫,中场,和转发),以评估WCS和超过特定阈值花费的时间在不同人群中如何变化。
    方法:在2022-23赛季收集了来自意大利职业足球俱乐部31名球员的数据。微技术设备在比赛期间跟踪身体活动。球员按位置分类,WCS是使用1分钟内的滚动平均值确定的。计算了TD和HSR在WCS的80%和90%以上花费的时间。
    结果:与第一团队相比,U19团队表现出更高的HSRWCS(〜63m·min-1vs〜56m·min-1)。中场球员记录了最高的TDWCS(~208m·min-1),前锋表现出最高的高铁WCS(~70米·分钟-1)。第一支球队在TDWCS的80%(~6分钟)和90%(~1分钟)以上花费的时间明显更多。中场球员花费的时间明显超过TDWCS的80%(~7分钟),而远期高于80%(~2分钟)的高铁WCS。
    结论:该研究强调,单独使用WCS可能不足以捕获真实的匹配强度。考虑到花费在特定阈值以上的时间提供了额外的见解(即,级别之间的差异和位置)。从业者应考虑WCS和花费在个性化培训处方阈值以上的时间,反映了角色的差异。
    OBJECTIVE: This study aimed to enhance the understanding of soccer match peak demands by describing worst-case scenario (WCS) and time spent above 80% and 90% of the WCS for total distance (TD) and high-speed running (HSR). The investigation considered playing level (first team vs under-19 [U19] team) and playing position (center backs, fullbacks, midfielders, and forwards) to assess how WCS and the time spent above specific thresholds vary across different populations.
    METHODS: Data from 31 players in a professional Italian soccer club were collected during the 2022-23 season. Microtechnology devices tracked physical activity during matches. Players were categorized by position, and WCS was determined using rolling averages over a 1-minute period. Time spent above 80% and 90% of WCS for TD and HSR was calculated.
    RESULTS: The U19 team exhibited higher HSR WCS compared with the first team (∼63 m·min-1 vs ∼56 m·min-1). Midfielders recorded the highest TD WCS (∼208 m·min-1), and forwards exhibited the highest HSR WCS (∼70 m·min-1). The first team spent significantly more time above 80% (∼6 min) and 90% (∼1 min) of TD WCS. Midfielders spent significantly more time above the 80% (∼7 min) of TD WCS, while forwards above the 80% (∼2 min) of HSR WCS.
    CONCLUSIONS: The study emphasizes that WCS used alone may not sufficiently capture real match intensity. Considering the time spent above specific thresholds provides additional insights (ie, between-levels differences and position). Practitioners should consider both WCS and time spent above thresholds for individualized training prescriptions, reflecting differences in playing roles.
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  • 文章类型: Journal Article
    目的:本研究比较了准备时间,错误,满意,在一项随机研究中,与两种需要重建的RSV疫苗(VRR1和VRR2)相比,单盲时间和运动研究。方法:药剂师,护士,和药学技术人员被随机分配到三种疫苗的制备顺序。参与者阅读说明,然后连续制备三种疫苗,其间有3至5分钟的洗脱期。由训练有素的药剂师对准备时间和错误进行视频记录和审查,使用预定义,疫苗特异性检查表。参与者的人口统计,对疫苗制备的满意度,并记录疫苗偏好。受试者内方差分析用于比较准备时间。混合效应泊松和有序逻辑回归模型用于比较准备错误的数量和满意度得分,分别。结果:63名药师(60%),护士(35%)和药学技术人员(5%)参加了美国四个地点的活动。PFS的每个剂量的最小二乘平均准备时间比VRR1快141.8秒(95%CI:156.8,126.7;p<0.0001),比VRR2快103.6秒(118.7,88.5;p<0.0001),比合并的VRR快122.7秒(95%CI:134.2,111.2;p<0.0001)。PFS的总体满意度(“非常”和“非常”)为87.3%,VRR1为28.6%,VRR2为47.6%。大多数参与者(81.0%)更喜欢PFS疫苗。局限性:这项研究由于无法完全失明的观察者而受到限制。为了尽量减少秩序的影响,我们使用了3序列块设计,然而,疫苗的制备顺序可能影响结局.参与者被评估一次,而如果进行重复制备,则每种疫苗的训练效率可能会提高。结论:PFS疫苗可以大大简化疫苗制备过程,允许管理员每小时准备的剂量几乎是小瓶和注射器系统的四倍。
    UNASSIGNED: The current study compared preparation time, errors, satisfaction, and preference for a prefilled syringe (PFS) versus two RSV vaccines requiring reconstitution (VRR1 and VRR2) in a randomized, single-blinded time and motion study.
    UNASSIGNED: Pharmacists, nurses, and pharmacy technicians were randomized to a preparation sequence of the three vaccines. Participants read instructions, then consecutively prepared the three vaccines with a 3-5-min washout period in between. Preparations were video recorded and reviewed by a trained pharmacist for preparation time and errors using predefined, vaccine-specific checklists. Participant demographics, satisfaction with vaccine preparation, and vaccine preference were recorded. Within-subjects analysis of variance was used to compare preparation time. Mixed-effects Poisson and ordered logistic regression models were used to compare the number of preparation errors and satisfaction scores, respectively.
    UNASSIGNED: Sixty-three pharmacists (60%), nurses (35%), and pharmacy technicians (5%) participated at four sites in the United States. The least squares mean preparation time per dose for PFS was 141.8 s (95% CI = 156.8-126.7; p <.0001) faster than for VRR1, 103.6 s (95% CI = 118.7-88.5; p <.0001) faster than for VRR2, and 122.7 s (95% CI = 134.2-111.2; p <.0001) faster than the pooled VRRs. Overall satisfaction (combined \"Very\" and \"Extremely\") was 87.3% for PFS, 28.6% for VRR1, and 47.6% for VRR2. Most participants (81.0%) preferred the PFS vaccine.
    UNASSIGNED: The study is limited by the inability to completely blind observers. To minimize the effects of order, we utilized a 3-sequence block design; however, the order in which the vaccines were prepared may have affected outcomes. Participants were assessed once, whereas if repeated preparations were performed there may have been trained efficiencies gained for each vaccine.
    UNASSIGNED: PFS vaccines can greatly simplify the vaccine preparation process, allowing administrators to prepare almost four times more doses per hour than with vial and syringe systems.
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