{Reference Type}: Journal Article {Title}: Effect of fatigue on knee biomechanics during the sidestep cutting manoeuvre: A modelling approach. {Author}: Bedo BLS;Catelli DS;Moraes R;Pereira DR;Lamontagne M;Santiago PRP; {Journal}: J Sports Sci {Volume}: 42 {Issue}: 12 {Year}: 2024 Jun 2 {Factor}: 3.943 {DOI}: 10.1080/02640414.2024.2386206 {Abstract}: Loading both lateral and medial compartments is crucial to understanding the effect of muscle fatigue during sidestep cutting. The present study investigated the changes in tibiofemoral contact forces in the medial and lateral compartments and the muscle force contributions during the sidestep-cutting manoeuvre after a handball-specific fatigue protocol. Twenty female handball athletes performed three trials of the sidestep-cutting manoeuvre before (baseline) and after the fatigue protocol. Motion capture and ground reaction forces were measured, and the data were processed in OpenSim. The variables were compared using statistical parametric mapping (SPM), with a significance level of pā€‰<ā€‰0.05. The results showed a decreased knee flexion angle during fatigue in the early stance phase. In addition, the post-fatigue analysis demonstrated significantly reduced forces in vasti muscles. Similarly, during fatigue, the SPM analysis showed decreased tibiofemoral contact forces in the vertical and anterior directions. Vertical force applied to both medial and lateral condyles demonstrated a significant reduction after the fatigue protocol. These results indicated that forces applied to the tibiofemoral joint were reduced following the fatigue protocol compared to the baseline values. However, no consistent evidence exists that fatigue increases the risk of knee injuries.