Sexual dysfunction, physiological

性功能障碍, 生理学
  • 文章类型: Journal Article
    女性性功能障碍通常发生在更年期过渡和更年期后,由于荷尔蒙,生理,和社会心理因素。性欲对老年女性很重要;然而,许多人不愿意为他们的性问题寻求治疗。临床医生应善于管理和治疗该人群的性功能障碍。一种多维治疗方法,解决可改变的心理,物理,和社会心理因素是必要的,以改善性功能和生活质量。
    Female sexual dysfunction commonly occurs during the menopause transition and post-menopause due to hormonal, physiologic, and psychosocial factors. Sexuality is important to aging women; however, many are reluctant to seek treatment for their sexual concerns. Clinicians should be adept at managing and treating sexual dysfunction in this population. A multi-dimensional treatment approach that addresses modifiable mental, physical, and psychosocial factors is warranted to improve sexual function and quality of life.
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  • 文章类型: Systematic Review
    背景:子宫内膜异位症患者的性功能应通过患者报告的结果指标(PROMs)进行评估,该指标具有较高的信度和效度。目的是研究用于评估子宫内膜异位症患者性功能的PROM,以改善他们对研究和临床实践的选择。
    方法:我们从2000年1月至2023年9月进行了系统的文献综述。检索所有研究,包括确诊子宫内膜异位症的女性,并评估性生活质量或性功能或性困扰。根据基于Consensus的健康测量仪器选择标准(COSMIN)建议,评估了用于性功能障碍的PROM的不同特性。评估的特性是:结构有效性,内部一致性,跨文化有效性,可靠性,测量误差,标准有效性,构造效度,和响应性。该文献综述在Prospero上注册为2018CRD42018102278。
    结果:纳入74篇评估性功能的文章。在25个评估性功能的PROM中,女性性功能指数(FSFI)是最常用的(34/74[45.9%]项),其次是女性性困扰量表(9/74[12.2%]项)和性活动问卷(SAQ)(8/74[10.8%]项)。最常用的测量属性是“假设检验”和“响应性”。具有这两种测量特性的高水平证据的PROM是FSFI,SAQ,短性功能量表,女性性满意度量表,性生活质量-女性,女性性功能简介,和女性问卷中的性健康结果。FSFI问卷似乎更适合评估药物治疗,和用于评估手术治疗的SAQ。只有一种仪器是子宫内膜异位症特有的(视力障碍量表[SIDI]的主观影响)。
    结论:在这篇关于子宫内膜异位症性功能评估问卷的系统文献综述中,根据COSMIN标准,FSFI和SAQ问卷具有最佳的测量特性。FSFI问卷似乎适合评估医疗,和SAQ进行手术治疗。SIDI是唯一的具体问卷,但其响应性仍有待定义。
    BACKGROUND: Sexual function of patients with endometriosis should be assessed by patient-reported outcome measures (PROMs) that present high reliability and validity. The objective was to study the PROMs used to assess sexual function for patients with endometriosis to improve their selection for research and clinical practice.
    METHODS: We performed a systematic literature review from January 2000 to September 2023. All studies including women with confirmed endometriosis and assessing sexual quality of life or sexual function or sexual distress were retrieved. Different properties of PROMs used for sexual dysfunction were assessed according to the COnsensus-based Standards for the selection of health Measurement Instruments (COSMIN) recommendations. Properties evaluated were: structural validity, internal consistency, cross-cultural validity, reliability, measurement error, criterion validity, construct validity, and responsiveness. This literature review was registered on Prospero as 2018 CRD42018102278.
    RESULTS: Seventy-four articles with evaluation of sexual function were included. Of the 25 PROMs assessing sexual function, the Female Sexual Function Index (FSFI) was the most frequently used (34/74 [45.9%] items), followed by the Female Sexual Distress Scale (9/74 [12.2%] items) and the Sexual Activity Questionnaire (SAQ) (8/74 [10.8%] items). The most commonly used measurement properties were \"hypothesis testing\" and \"responsiveness\". The PROMs with a high level of evidence for these two measurement properties were the FSFI, the SAQ, the Short Sexual Functioning Scale, the Sexual Satisfaction Scale for Women, Sexual Quality of Life-Female, the Brief Profile of Female Sexual Function, and the Sexual Health Outcomes in Women Questionnaire. The FSFI questionnaire appeared to be more relevant for evaluating medical treatment, and the SAQ for evaluating surgical treatment. Only one instrument was specific to endometriosis (the Subjective Impact of Dyspareunia Inventory [SIDI]).
    CONCLUSIONS: In this systematic literature review of sexual function assessment questionnaires in endometriosis, the FSFI and the SAQ questionnaires emerged as having the best measurement properties according to the COSMIN criteria. The FSFI questionnaire appears to be suited for evaluating medical treatment, and the SAQ for surgical treatment. The SIDI is the only specific questionnaire, but its responsiveness remains to be defined.
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  • 文章类型: Journal Article
    女性性功能障碍(FSD)是全球的重要公共卫生问题。鉴于目前国内尚无针对FSD诊治的标准参考,中国整形美容协会科技创新与器官整复分会组织国内性医学领域、妇产科学领域、康复治疗领域、心理卫生领域以及中医领域的专家,结合国内外FSD研究现状制定本共识,以期为FSD临床诊治提供参考。本共识的制定严格遵循指南共识制定的通用原则,并按照循证医学原则划分证据等级并给出推荐等级。本共识定义了FSD,并对FSD的流行病学进行了概述,明确了性反应周期的四阶段学说以及FSD的常见病因与高危因素。本共识参考国际上普遍采用的分类原则对FSD进行了分类,包括:性欲减退功能障碍、性唤起功能障碍、性高潮功能障碍、生殖器或盆腔疼痛和插入障碍、与盆底功能障碍性疾病有关的性功能障碍、其他特指及未特指的性功能障碍。本共识对FSD的诊断和治疗提出了原则性的指导。FSD的诊断要重视病史采集,并合理应用性功能评估量表或问卷;体格检查尤其是生殖系统专科检查是必不可少的,必要时要进行辅助检查。FSD的治疗包括一般干预、心理干预(包含性感集中疗法、认知行为疗法、正念疗法等)、药物治疗(其中的激素治疗包含雌激素治疗和雄激素治疗)、阴道润滑剂和保湿剂、自我性刺激训练、盆底物理疗法(包含盆底肌训练、阴道扩张、手法按摩、电刺激和生物反馈等)、原发疾病的治疗、中医药治疗。.
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  • 文章类型: Review
    背景:前列腺癌患者在治疗后出现明显的性功能障碍,这对他们和他们的伴侣在心理上产生了负面影响,紧张他们的关系。
    目的:我们召集了一个国际小组,旨在制定指导临床医生的指南,患者和伴侣了解前列腺癌治疗(PCT)对患者和伴侣性健康的影响,他们的关系,以及前列腺癌(PC)幸存者的生物心理社会康复。
    方法:指南小组包括国际专家研究人员和临床医生,和指导方法学家。对文献进行了系统的回顾,使用OvidMEDLINE,Scopus,CINAHL,心理信息,LGBT生活,根据Cochrane干预措施系统审查手册进行了Embase数据库(1995-2022年)。研究选择基于系统评价和荟萃分析(PRISMA)指南的首选报告项目。每个陈述都被分配了一个证据强度(A-C)和一个建议级别(强,中度,有条件)基于利益/风险评估。数据综合包括对被认为质量足够的研究的荟萃分析(3),使用测量工具评估系统评论(AMSTAR)。
    结果:制定了前列腺癌患者性保健指南,基于现有证据和国际小组的专业知识。
    结果:指南考虑了患者的文化,民族,种族多样性。他们关注具有不同性取向和性别认同的个人的独特需求。该指南基于文献综述,PCT术后性恢复的理论模型,和6个原则,促进临床医生发起的对性结果的现实期望的讨论,并通过生物心理社会康复减轻性副作用。47份声明涉及性心理,关系,和功能领域,除了关于生活方式改变的声明,评估,提供者教育,以及在PC幸存者中提供性健康护理的系统性挑战。
    结论:该指南为临床医生提供了针对前列腺癌患者的性健康护理的综合方法。
    UNASSIGNED:这项研究的力量是对前列腺癌性功能障碍和康复的现有证据的综合评估,连同可用的专业知识,最好的基础临床实践。局限性在于支持干预措施的证据的差异以及缺乏对低收入和中等收入国家前列腺癌患者面临的问题的研究。
    结论:指南记录了PCT令人痛苦的性后遗症,提供基于证据的性康复建议,并概述未来研究的领域。
    Patients with prostate cancer suffer significant sexual dysfunction after treatment which negatively affects them and their partners psychologically, and strain their relationships.
    We convened an international panel with the aim of developing guidelines that will inform clinicians, patients and partners about the impact of prostate cancer therapies (PCT) on patients\' and partners\' sexual health, their relationships, and about biopsychosocial rehabilitation in prostate cancer (PC) survivorship.
    The guidelines panel included international expert researchers and clinicians, and a guideline methodologist. A systematic review of the literature, using the Ovid MEDLINE, Scopus, CINAHL, PsychINFO, LGBT Life, and Embase databases was conducted (1995-2022) according to the Cochrane Handbook for Systematic Reviews of Interventions. Study selection was based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Each statement was assigned an evidence strength (A-C) and a recommendation level (strong, moderate, conditional) based on benefit/risk assessment. Data synthesis included meta-analyses of studies deemed of sufficient quality (3), using A Measurement Tool to Assess Systematic Reviews (AMSTAR).
    Guidelines for sexual health care for patients with prostate cancer were developed, based on available evidence and the expertise of the international panel.
    The guidelines account for patients\' cultural, ethnic, and racial diversity. They attend to the unique needs of individuals with diverse sexual orientations and gender identities. The guidelines are based on literature review, a theoretical model of sexual recovery after PCT, and 6 principles that promote clinician-initiated discussion of realistic expectations of sexual outcomes and mitigation of sexual side-effects through biopsychosocial rehabilitation. Forty-seven statements address the psychosexual, relationship, and functional domains in addition to statements on lifestyle modification, assessment, provider education, and systemic challenges to providing sexual health care in PC survivorship.
    The guidelines provide clinicians with a comprehensive approach to sexual health care for patients with prostate cancer.
    The strength of the study is the comprehensive evaluation of existing evidence on sexual dysfunction and rehabilitation in prostate cancer that can, along with available expert knowledge, best undergird clinical practice. Limitation is the variation in the evidence supporting interventions and the lack of research on issues facing patients with prostate cancer in low and middle-income countries.
    The guidelines document the distressing sexual sequelae of PCT, provide evidence-based recommendations for sexual rehabilitation and outline areas for future research.
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  • 文章类型: Journal Article
    前列腺癌患者在治疗后出现明显的性功能障碍,这对他们和他们的伴侣在心理上产生了负面影响,紧张他们的关系。
    我们召集了一个国际小组,旨在制定指导临床医生的指南,患者和伴侣了解前列腺癌治疗(PCT)对患者和伴侣性健康的影响,他们的关系,以及前列腺癌(PC)幸存者的生物心理社会康复。
    指南小组包括国际专家研究人员和临床医生,和指导方法学家。对文献进行了系统的回顾,使用OvidMEDLINE,Scopus,CINAHL,心理信息,LGBT生活,根据Cochrane干预措施系统审查手册进行了Embase数据库(1995-2022年)。研究选择基于系统评价和荟萃分析(PRISMA)指南的首选报告项目。每个陈述都被分配了一个证据强度(A-C)和一个建议级别(强,中度,有条件)基于利益/风险评估。数据综合包括对被认为质量足够的研究的荟萃分析(3),使用测量工具评估系统评论(AMSTAR)。
    制定了前列腺癌患者性健康护理指南,基于现有证据和国际小组的专业知识。
    指南对患者的文化、民族,种族多样性。他们关注具有不同性取向和性别认同的个人的独特需求。该指南基于文献综述,PCT术后性恢复的理论模型,和6个原则,促进临床医生发起的对性结果的现实期望的讨论,并通过生物心理社会康复减轻性副作用。47份声明涉及性心理,关系,和功能领域,除了关于生活方式改变的声明,评估,提供者教育,以及在PC幸存者中提供性健康护理的系统性挑战。
    该指南为临床医生提供了全面的前列腺癌患者性健康护理方法。
    这项研究的力量是对前列腺癌性功能障碍和康复的现有证据的综合评估,连同可用的专业知识,最好的基础临床实践。局限性在于支持干预措施的证据的差异以及缺乏对低收入和中等收入国家前列腺癌患者面临的问题的研究。
    指南记录了PCT令人痛苦的性后遗症,提供基于证据的性康复建议,并概述未来研究的领域。WittmannD,MehtaA,麦考恩·E,etal.前列腺癌患者性保健指南:国际小组的建议。JSexMed2022;19:1655-1669。
    Patients with prostate cancer suffer significant sexual dysfunction after treatment which negatively affects them and their partners psychologically, and strain their relationships.
    We convened an international panel with the aim of developing guidelines that will inform clinicians, patients and partners about the impact of prostate cancer therapies (PCT) on patients\' and partners\' sexual health, their relationships, and about biopsychosocial rehabilitation in prostate cancer (PC) survivorship.
    The guidelines panel included international expert researchers and clinicians, and a guideline methodologist. A systematic review of the literature, using the Ovid MEDLINE, Scopus, CINAHL, PsychINFO, LGBT Life, and Embase databases was conducted (1995-2022) according to the Cochrane Handbook for Systematic Reviews of Interventions. Study selection was based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Each statement was assigned an evidence strength (A-C) and a recommendation level (strong, moderate, conditional) based on benefit/risk assessment, according to the nomenclature of the American Urological Association (AUA). Data synthesis included meta-analyses of studies deemed of sufficient quality (3), using A Measurement Tool to Assess Systematic Reviews (AMSTAR).
    Guidelines for sexual health care for patients with prostate cancer were developed, based on available evidence and the expertise of the international panel.
    The guidelines account for patients\' cultural, ethnic, and racial diversity. They attend to the unique needs of individuals with diverse sexual orientations and gender identities. The guidelines are based on literature review, a theoretical model of sexual recovery after PCT, and 6 principles that promote clinician-initiated discussion of realistic expectations of sexual outcomes and mitigation of sexual side-effects through biopsychosocial rehabilitation. Forty-seven statements address the psychosexual, relationship, and functional domains in addition to statements on lifestyle modification, assessment, provider education, and systemic challenges to providing sexual health care in PC survivorship.
    The guidelines provide clinicians with a comprehensive approach to sexual health care for patients with prostate cancer.
    The strength of the study is the comprehensive evaluation of existing evidence on sexual dysfunction and rehabilitation in prostate cancer that can, along with available expert knowledge, best undergird clinical practice. Limitation is the variation in the evidence supporting interventions and the lack of research on issues facing patients with prostate cancer in low and middle-income countries.
    The guidelines document the distressing sexual sequelae of PCT, provide evidence-based recommendations for sexual rehabilitation and outline areas for future research. Wittmann D, Mehta A, McCaughan E, et al. Guidelines for Sexual Health Care for Prostate Cancer Patients: Recommendations of an International Panel. J Sex Med 2022;19:1655-1669.
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  • 文章类型: Journal Article
    背景:第11版国际疾病统计分类(ICD-11)将于2022年生效。目前对GeSiD研究结果进行部分评估的目的是首次估计德国即将生效的诊断指南所定义的不同类型的性功能障碍的患病率。
    方法:在4955名男性和女性中进行了代表性的GeSiD研究,这些男性和女性属于来自德国各地居民登记办公室的双重分层随机抽样数据。参与率为30.2%。通过基于新的ICD-11指南的筛查工具,首次确定了各种类型的性功能障碍。
    结果:报告的一种或多种性问题的患病率,包括轻微的痛苦,在过去12个月中,男性为33.4%(95%置信区间[31.0;35.9]),女性为45.7%[43.0;48.4].约80.4%的男性和72.1%的女性表示,他们在过去一年中至少有过一次性接触。性功能障碍导致明显的痛苦,根据ICD-11指南,有13.3%[11.6;15.1]的性活跃男性报告(最常见的是,6.6%的勃起功能障碍和4.5%的早期射精),和17.5%[15.6;19.6]的性活跃女性(最常见的是,6.9%的性欲减退,5.8%的性高潮功能障碍)。女性的性高潮功能障碍大约是男性射精延迟的两倍。勃起功能障碍的患病率随着年龄的增长而增加,而早期射精的减少。女性感到与性活动相关的疼痛尤其受损。
    结论:这项研究的结果表明性功能障碍对性健康的重要性。该研究为新的ICD-11指南提供了第一个患病率估计,同时为性功能障碍提供了一种筛查工具,可以在常规实践中经济地使用。
    BACKGROUND: The 11th edition of the International Statistical Classification of Diseases (ICD-11) is due to come into force in 2022. The goal of the present partial evaluation of the GeSiD study findings is to provide the first ever estimate of the prevalence of different types of sexual dysfunction in Germany as defined by the diagnostic guidelines that are soon to take effect.
    METHODS: The representative GeSiD study was carried out in 4955 men and women who belonged to a doubly stratified random sample of data from residence registration offices across Germany. The participation rate was 30.2%. Various types of sexual dysfunction were ascertained for the first time by means of a screening instrument based on the new ICD-11 guidelines.
    RESULTS: The reported prevalence of one or more sexual problems, including mild distress, in the previous 12 months was 33.4% in men (95% confidence interval [31.0; 35.9]) and 45.7% in women [43.0; 48.4]. Some 80.4% of men and 72.1% of women stated that they had had at least one sexual contact in the past year. Sexual dysfunction causing marked distress, as per the ICD-11 guidelines, was reported by 13.3% [11.6; 15.1] of the sexually active men (most commonly, erectile dysfunction in 6.6% and early ejaculation in 4.5%), and by 17.5% [15.6; 19.6] of the sexually active women (most commonly, hypoactive sexual desire in 6.9% and orgasmic dysfunction in 5.8%). Orgasmic dysfunction was approximately twice as common in women as delayed ejaculation was in men. The prevalence of erectile dysfunction increased with age, while that of early ejaculation decreased. Women felt particularly impaired by pain associated with sexual activity.
    CONCLUSIONS: The findings of this study indicate the importance of sexual dysfunction as an obstacle to sexual health. The study provides the first prevalence estimates for the new ICD-11 guidelines and simultaneously offers a screening instrument for sexual dysfunction that can be used economically in routine practice.
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  • 文章类型: Case Reports
    Sexual dysfunction has long been overlooked in the broader context of sexual and reproductive health services. As a result, and in the absence of international sexual dysfunction treatment guidelines, recommendations have instead been developed by a variety of professional associations, worldwide.
    We conducted a mapping of existing recommendations addressing a wide array of conditions related to sexual function/dysfunction.
    We contacted 25 professional associations from around the world and held an online open call for guidelines.
    Eligible submissions had to provide recommendations on treatment related to male or female sexual dysfunction.
    Twelve guidelines from 11 associations were included. Of the 195 recommendations extracted, 61% were related to men, 53% were related specifically to treatment, and 48% did some form of evidence assessment.
    Recommendations from this exercise are provided for WHO, international and national research institutions, ministries of health, and professional associations. Gonsalves L, Cottler-Casanova S, VanTreeck K, et al. Results of a World Health Organization Scoping of Sexual Dysfunction-Related Guidelines: What Exists and What Is Needed. J Sex Med 2020;17:2518-2521.
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  • 文章类型: Consensus Development Conference
    暂无摘要。
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  • 文章类型: Journal Article
    早泄(PE)是男性最常见的性功能障碍,和最近定义的。PE通常被患者错误地认为是纯粹的心理症状:缺乏对病理生理学和治疗方法的认识通常会导致患者的辞职。让体育成为最不被诊断的性投诉。然而,在过去的几十年中,越来越多的证据支持了几种有机因素,并且已经提出了几种定义来涵盖PE的所有定义特征。在意大利男科和性医学学会(SIAMS)的本文件中,我们就定义提出33项建议,病理生理学,PE的治疗和管理旨在改善患者护理。这些以证据为基础的临床指南在继发于器质性和心理性疾病的PE的情况下提供了必要的最新指导。比如前列腺炎症,内分泌失调,和其他性功能障碍,并建议如何以夫妇为中心的方法将药物疗法和认知行为疗法联系起来。新的治疗选择,以及组合和标签外治疗,也有描述。
    Premature ejaculation (PE) is the most prevalent male sexual dysfunction, and the most recently defined. PE is often mistakenly considered a purely psychosexological symptom by patients: the lacking awareness in regards to the pathophysiology and treatments often lead to resignation from the patients\' side, making PE the most underdiagnosed sexual complaint. However, an ever-growing body of evidence supporting several organic factors has been developed in the last decades and several definitions have been suggested to encompass all defining features of PE. In the present document by the Italian Society of Andrology and Sexual Medicine (SIAMS), we propose 33 recommendations concerning the definition, pathophysiology, treatment and management of PE aimed to improve patient care. These evidence-based clinical guidelines provide the necessary up-to-date guidance in the context of PE secondary to organic and psychosexological conditions, such as prostate inflammation, endocrine disorders, and other sexual dysfunctions, and suggest how to associate pharmacotherapies and cognitive-behavioral therapy in a couple-centered approach. New therapeutic options, as well as combination and off-label treatments, are also described.
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  • 文章类型: Journal Article
    Background: Obesity is a chronic disease with several co-morbidities that increase morbidity and mortality and decrease quality of life. Psychopathologies are an important group of co-morbidities. In this study, it was aimed to search for the presence of depression and sexual dysfunction in patients with obesity, examine impact of obesity on marital adjustment, and highlight those important problems that are usually overlooked. Methods: Fifty patients who were seen in the obesity outpatient clinic in a random month as case group and gender-matched 50 healthy individuals as control group were included in the study. The inclusion criteria were body mass index (BMI) ≥30 kg/m2 and having a sexual partner. The exclusion criteria were having psychiatric/mental or any other chronic illness, using medication that would affect sexual functions, and alcohol/substance abuse. After recording the sociodemographic data, patients were asked to take three internationally validated questionnaires: The Arizona Sexual Experience Scale (ASEX), Dyadic Adjustment Scale (DAS), and Beck Depression Inventory (BDI). Results were analyzed using SPSS. Results: Fifty patients with obesity as case group and 50 normal weight healthy persons as control group were included in the study. BMI and BDI score were significantly higher in the case group than in the control group. DAS score was lower in the case group for consensus and affectional expression than the control group but there was no difference for satisfaction, cohesion, or total score between the groups. ASEX score was higher in the case group than in the control group. Conclusion: Patients with obesity have dyadic consensus problems with their partners. Their excessive weight causes distress and difficulty in expressing their feelings and usually results in marital problems and depression. Evaluation of the patient with a multidisciplinary approach in obesity centers will allow patients to be analyzed in every aspect of obesity including these issues and contribute to the success of the treatment.
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