■血吸虫病是由血吸虫属的血吸虫引起的急性和慢性寄生虫病。目前用于治疗血吸虫病的药物与一些副作用有关。
■这项系统研究的目的是概述基于纳米颗粒的血吸虫引起的疾病的治疗。
■在目前以“血吸虫”为关键词的系统研究中,\"寄生\",“抗血吸虫活性”,\"纳米粒子\",\"金属纳米粒子\",\"银纳米粒子\",\"金纳米粒子\",“聚合物纳米颗粒”,\"PLGA纳米粒子\",“纳米乳液”,\“体外\”,和来自五个英语数据库的“体内”,包括ScienceDirect,europePMC,PubMed,Scopus,奥维德,从2000年到2022年,两名研究人员对Cochrane进行了搜索。
■在最初的搜索中,选择了250项研究。根据纳入和排除标准,删除副本后,最终选择了27篇文章,无关,和包含全文的文章。在本文中,用于血吸虫的纳米颗粒最多的是金纳米颗粒(22%)。
■结果表明各种纳米颗粒的高电位,包括金属纳米颗粒,对抗血吸虫.此外,纳米颗粒的显着抗血吸虫活性表明它们在不同领域中用于消除这种病原微生物,因此它可以用作制备抗血吸虫化合物的有效候选物,因为这些化合物的副作用比化学药物少。TherResClinExp.2023年;XX:XXX-XXX)。
UNASSIGNED: Schistosomiasis is an acute and chronic parasitic disease caused by blood flukes of the genus
Schistosoma. The current drugs for treating schistosomiasis are associated with some side effects.
UNASSIGNED: The aim of this systematic study was an overview of the treatment of diseases caused by
Schistosoma based on nanoparticles.
UNASSIGNED: In the present systematic research with keywords \"
Schistosoma\", \"parasitism\", \"anti-
Schistosoma activity\", \"nanoparticles\", \"metal nanoparticles\", \"silver nanoparticles\", \"gold nanoparticles\", \"polymer nanoparticles\", \"PLGA nanoparticles\", \"nanoemulsions\", \"in vitro\", and \"in vivo\" from five English-language databases, including ScienceDirect, europePMC, PubMed, Scopus, Ovid, and Cochrane were searched from 2000 to 2022 by 2 researchers.
UNASSIGNED: In the initial search, 250 studies were selected. Based on the inclusion and exclusion criteria, 27 articles were finally selected after removing duplicate, unrelated, and articles containing full text. In present article, the most nanoparticles used against
Schistosoma were gold nanoparticles (22%).
UNASSIGNED: The results indicate the high potential of various nanoparticles, including metal nanoparticles, against Schistosoma. Also, the remarkable anti-schistosomal activity of nanoparticles suggests their use in different fields to eliminate this pathogenic microorganism so that it can be used as an effective candidate in the preparation of anti-schistosomal compounds because these compounds have fewer side effects than chemical drugs. Ther Res Clin Exp. 2023; XX:XXX-XXX).