红景天属,中国传统中药和藏医的组成部分,具有广泛的应用。这个属含有关键化合物,如人参皂苷,多糖,和类黄酮,具有抗炎作用,抗氧化剂,低血糖,免疫增强,和抗缺氧特性。作为一种重要的原材料,红景天在中国贡献了24种中成药和481种保健食品,在保健食品领域发现广泛应用。最近,多糖已成为天然产物研究的焦点,随着跨越医学的应用,食物,和材料部门。尽管如此,有必要对红景天属多糖(TGRP)的多糖进行全面和系统的综述。本研究对国内外文献进行了系统的回顾,评估红景天多糖的研究进展和化学功能价值。它涉及到隔离,净化,和鉴定各种均质多糖,然后详细分析它们的化学结构,药理活性,和分子机制,TGRP的构效关系(SAR)。讨论包括分子量的影响,单糖组成,以及它们的生物活性上的糖苷键,如硫酸化和羧甲基化等。这些分析对于加深对红景天的理解和促进TGRP的开发和开发至关重要。为进一步调查TGRP及其资源利用提供参考。
The genus Rhodiola L., an integral part of traditional Chinese medicine and Tibetan medicine in China, exhibits a broad spectrum of applications. This genus contains key compounds such as ginsenosides,
polysaccharides, and flavonoids, which possess anti-inflammatory, antioxidant, hypoglycaemic, immune-enhancing, and anti-hypoxic properties. As a vital raw material, Rhodiola L. contributes to twenty-four kinds of Chinese patent medicines and 481 health food products in China, finding extensive application in the health food sector. Recently,
polysaccharides have emerged as a focal point in natural product research, with applications spanning the medicine, food, and materials sectors. Despite this, a comprehensive and systematic
review of
polysaccharides from the genus Rhodiola L.
polysaccharides (TGRPs) is warranted. This study undertakes a systematic
review of both domestic and international literature, assessing the research advancements and chemical functional values of
polysaccharides derived from Rhodiola rosea. It involves the isolation, purification, and identification of a variety of homogeneous polysaccharides, followed by a detailed analysis of their chemical structures, pharmacological activities, and molecular mechanisms, structure-activity relationship (SAR) of TGRPs. The discussion includes the influence of molecular weight, monosaccharide composition, and glycosidic bonds on their biological activities, such as sulfation and carboxymethylation et al. Such analyses are crucial for deepening the understanding of Rhodiola rosea and for fostering the development and exploitation of TGRPs, offering a reference point for further investigations into TGRPs and their resource utilization.