Parastomal hernia

造口旁疝
  • 文章类型: Journal Article
    目的:描述和评估机器人改良Sugarbaker技术与腹膜内垫网(IPUM)修复与回肠导管(ICPSH)相关的造口旁疝的安全性和可行性。
    方法:本回顾性研究,单中心队列研究分析了在2021年7月至2023年7月期间使用改良SugarbakerIPUM技术进行机器人ICPSH修复的15例成年患者的数据.主要终点是疝气复发率和30天发病率。次要终点包括住院时间,转换为开放手术,重新接纳30天,再手术30天.
    结果:患者平均年龄为69.1岁,53.3%为女性。大多数患者(86.6%)接受了根治性膀胱切除术作为指征手术。平均手术时间为249分钟,没有转换为开放手术。30天并发症发生率为26.7%,平均住院时间为3.6天。没有疝气复发,肾积水,在平均15.2个月的随访期间,影像学检查发现肌酐升高或导管扩张提示引流不良.
    结论:机器人改良SugarbakerIPUM技术对于IC患者的PSH修复似乎是安全可行的,有希望的短期结果。需要进行更大队列和更长随访的进一步研究,以确认其长期疗效并确定其在ICPSH管理中的作用。
    OBJECTIVE: To describe and evaluate safety and feasibility of the robotic modified Sugarbaker technique with intraperitoneal underlay mesh (IPUM) for repairing parastomal hernias associated with ileal conduits (ICPSH).
    METHODS: This retrospective, single-center cohort study analyzed data from 15 adult patients who underwent robotic ICPSH repair using the modified Sugarbaker IPUM technique between July 2021 and July 2023. The primary endpoints were hernia recurrence rates and 30-day morbidity. Secondary endpoints included length of stay, conversion to open surgery, 30-day readmission, and 30-day reoperation.
    RESULTS: The mean patient age was 69.1 years, and 53.3% were female. Most patients (86.6%) had undergone radical cystectomy as the index surgery. The mean operative time was 249 min, with no conversions to open surgery. The 30-day complication rate was 26.7%, and the mean hospital stay was 3.6 days. No hernia recurrences, hydronephrosis, rise in creatinine or distended conduit on imaging suggesting poor drainage were observed during a mean follow-up of 15.2 months.
    CONCLUSIONS: The robotic modified Sugarbaker IPUM technique appears safe and feasible for PSH repair in IC patients, with promising short-term outcomes. Further studies with larger cohorts and longer follow-up are needed to confirm its long-term efficacy and establish its role in ICPSH management.
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  • 文章类型: Journal Article
    目的:综述Lap-re-Do技术治疗大型造口旁疝的安全性和有效性。
    方法:回顾性分析2010年5月至2019年12月在复旦大学附属华山医院行Lap-re-Do技术治疗的81例大型造口旁疝患者的复发及并发症。患者应该能够完成随访。有了这样的标准,我们包括40例Lap-re-DoKeyhole患者和41例Lap-re-DoSugarbaker患者。观察时间定义为复发时间,死亡,或最后一次非事件访问。
    结果:在大型造口旁疝中,Lap-re-Do的复发率为25.9%,并发症发生率为16.0%,平均随访时间41.1±17.8个月,再次手术率为9.9%。Lap-re-DoKeyhole修复后的复发率为40%(16/40),Lap-re-DoSugarbaker修复后的复发率为12.2%(5/41)。术后并发症发生率为12.5%,术后并发症发生率为19.5%,术后并发症发生率为19.5%。随访期间,术后并发症发生率为15%,术后并发症发生率为4.9%。大多数再次手术以复发为标志。
    结论:大型造口旁疝仍难以治疗。建议将Lap-re-DoSugarbaker作为关闭疝气环的适当程序,移除冗长的结肠造口术,并有效降低复发率和并发症发生率。
    OBJECTIVE: To review the safety and efficacy of Lap-re-Do technique in the treatment of large parastomal hernia.
    METHODS: We retrospectively analyzed the recurrence and complications of 81 patients with large parastomal hernia who underwent Lap-re-Do technique in Huashan Hospital of Fudan University from May 2010 to December 2019. And the patients should be able to complete follow-up. With such criteria, we included 40 Lap-re-Do Keyhole patients and 41 Lap-re-Do Sugarbaker patients. Observation time was defined as time to recurrence, death, or last nonevent visit.
    RESULTS: In large parastomal hernias, Lap-re-Do had a recurrence rate of 25.9% and complication rate of 16.0%, and reoperation rate of 9.9% during the average follow-up time of 41.1 ± 17.8 months. Recurrence rates were 40% (16/40) after Lap-re-Do Keyhole repair and 12.2% (5/41) after Lap-re-Do Sugarbaker repair. Complication rates were 12.5% after Lap-re-Do keyhole and 19.5% after Lap-re-Do Sugarbaker repair Re-operation rates referred to Lap-re-Do keyhole repair were 15% and Lap-re-Do Sugarbaker repair 4.9% during follow-up.The majority of reoperations were indicated by recurrence.
    CONCLUSIONS: Large parastomal hernias are still difficult to be treated. Lap-re-Do Sugarbaker is recommended as an appropriate procedure to close the hernia ring, removing the lengthy colostomy, and effectively reduce recurrence and complication rates.
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  • 文章类型: Journal Article
    背景:本研究探讨了在开放根治性膀胱切除术和回肠导管改道期间预防性网状物植入在预防造口旁疝(PH)中的疗效。尽管PH是常见的并发症,预防方法的开发不足。
    方法:一名飞行员,单中心,前瞻性队列研究涉及5例接受网状物植入手术的患者。监测人口统计学和临床特征,包括PH的发生率,操作时间,失血,和住院时间。
    结果:在术后9.1±3.2个月的平均随访期间,在患者组中未观察到PH的发生。尽管在涉及小肠开放的手术区域植入异物存在风险,未发现感染并发症.
    结论:根治性膀胱切除术中的预防性网状物植入回肠导管分流似乎是预防PH的有效措施。需要进一步的广泛研究来明确确认在这种情况下使用网状物的有效性和安全性。
    BACKGROUND: This study examines the efficacy of prophylactic mesh implantation during open radical cystectomy with ileal conduit diversion in preventing parastomal hernias (PH). Despite PH being a common complication, prophylactic methods have been underexplored.
    METHODS: A pilot, single-center, prospective cohort study was conducted involving five patients undergoing surgery with mesh implantation. Demographic and clinical characteristics were monitored, including the incidence of PH, operation time, blood loss, and hospitalization duration.
    RESULTS: During the mean follow-up period of 9.1±3.2 months post-operation, no occurrences of PH were observed in the patient group. Despite the risks associated with implanting foreign material in an area of surgery involving open small intestine, no infectious complications were noted.
    CONCLUSIONS: Prophylactic mesh implantation in radical cystectomy with ileal conduit diversion appears to be an effective preventive measure against PH. Further extensive studies are required to definitively confirm the efficacy and safety of mesh use in this context.
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  • 文章类型: Journal Article
    我们评估了预防性生物网片对膀胱切除术和回肠导管(IC)患者造口旁疝(PSH)发展的影响。
    第三阶段,随机,对照试验(NCT02439060)纳入了2015年至2021年间在南加州大学接受膀胱切除术和IC的146例患者。随访为每4至6个月一次的体格检查和CT,直至2年。患者以1:1的比例随机分配,使用皮下腹膜内技术与标准IC接受FlexHD预防性生物网状物。主要终点是放射性PSH的时间,次要结局包括有/无手术干预的临床PSH和网片相关并发症.
    两组在基线临床特征方面相似。所有手术和网状物放置均进行,无任何术中并发症。接受网状物的患者的中位手术时间延长了31分钟,但没有统计学上的显著差异(363分钟vs332分钟,P=.16)。中位随访时间为24个月,放射学和临床PSHs检测到37例(18个网状受体vs19个对照)和16例(两组8名受试者)患者,放射学和临床PSH的中位时间为8.3和15.5个月,分别。未报告明确的网状物相关不良事件。五名患者(网状物中3名,对照臂中2名)需要手术PSH修复。网状组和对照组的无放射性PSH生存率在1年分别为74%和75%,在2年分别为69%和62%。
    在IC构建时实施生物网片是安全的,在手术后2年内没有明显的保护作用。
    UNASSIGNED: We assessed the effect of prophylactic biologic mesh on parastomal hernia (PSH) development in patients undergoing cystectomy and ileal conduit (IC).
    UNASSIGNED: This phase 3, randomized, controlled trial (NCT02439060) included 146 patients who underwent cystectomy and IC at the University of Southern California between 2015 and 2021. Follow-ups were physical exam and CT every 4 to 6 months up to 2 years. Patients were randomized 1:1 to receive FlexHD prophylactic biological mesh using sublay intraperitoneal technique vs standard IC. The primary end point was time to radiological PSH, and secondary outcomes included clinical PSH with/without surgical intervention and mesh-related complications.
    UNASSIGNED: The 2 arms were similar in terms of baseline clinical features. All surgeries and mesh placements were performed without any intraoperative complications. Median operative time was 31 minutes longer in patients who received mesh, yet with no statistically significant difference (363 vs 332 minutes, P = .16). With a median follow-up of 24 months, radiological and clinical PSHs were detected in 37 (18 mesh recipients vs 19 controls) and 16 (8 subjects in both arms) patients, with a median time to radiological and clinical PSH of 8.3 and 15.5 months, respectively. No definite mesh-related adverse events were reported. Five patients (3 in the mesh and 2 in the control arm) required surgical PSH repair. Radiological PSH-free survival rates in the mesh and control groups were 74% vs 75% at 1 year and 69% vs 62% at 2 years.
    UNASSIGNED: Implementation of biologic mesh at the time of IC construction is safe without significant protective effects within 2 years following surgery.
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  • 文章类型: Journal Article
    这项英国研究旨在探索人们的生活体验,和自我管理的准物种膨胀。
    采访了17人,完成了在线调查61人。
    造口旁隆起对生活质量有不利影响,包括对造口功能的负面影响,日常活动,身体形象,身体上的亲密关系,和社会化;获得专家信息和支持以解决膨胀问题是不公平的;支持服装是最常见的自我管理干预措施;在造模膨胀的自我管理方面,关于什么运动是有益的或如何积极的,存在困惑;同伴支持不能替代高质量的专家支持。
    人们需要公平地获取信息和支持,以自我管理和治疗造模前膨胀。关于其他类型的自我管理干预措施的研究,例如,需要锻炼,这样人们就不必仅仅依靠支撑服装来自我管理造物的膨胀。
    UNASSIGNED: This United Kingdom study aimed to explore people\'s experiences of living with, and self-managing parastomal bulging.
    UNASSIGNED: Seventeen people were interviewed and 61 people completed an online survey.
    UNASSIGNED: Parastomal bulging has a detrimental impact on quality of life including a negative impact on stoma function, daily activities, body image, physical intimacy, and socialising; access to specialist information and support for addressing the problem of bulging was inequitable; support garments were the most common self-management intervention; there was confusion about what exercise would be beneficial or how being active would help in terms of parastomal bulging self-management; peer support is no substitute for high quality specialist support.
    UNASSIGNED: People need equitable access to information and support to self-manage and treat parastomal bulging. Research about other types of self-management interventions, for example, exercise is required so that people do not have to rely solely on support garments to self-manage parastomal bulging.
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  • 文章类型: Journal Article
    简介:腹壁疝手术旨在缓解症状并改善生活质量(QoL)。这个新的病人领导的研究的目标,帮助外科医生了解疝气对患者健康的影响。方法:由患者倡导者编制问卷。它通过社交媒体进行推广,以收集患者的匿名反馈。结果:共完成问卷264份。大多数受访者是女性(78.4%,n=207),来自英语国家(85.2%,n=225),并且患有造口旁疝(36.0%,n=95)或切口疝(28.0%,n=74)。受访者描述了他们的疝气是如何影响性亲密的,要么是因为不喜欢他们的外表,疼痛或疝气的实用性。他们报告说,他们的疝气限制了他们从事某些运动活动,相当比例的人也报告了对他们饮食的影响。结论:这项研究发现,除了功能问题,患有疝气会影响心理健康以及社会和身体关系。现有的疝气QoL工具在测量结果方面受到限制。没有全面的疝气特异性QoL工具,外科医生仍然难以准确评估不同治疗方式可能对患者产生的影响.
    Introduction: Abdominal wall hernia surgery aims to relieve symptoms and to improve quality of life (QoL). The aim of this novel patient led research, was to help surgeons understand how hernias impact on patients\' wellbeing. Methods: A questionnaire was developed by patient advocates. It was promoted through social media to gather anonymous feedback from patients. Results: 264 questionnaires were completed. The majority of the respondents were female (78.4%, n = 207), from English speaking countries (85.2%, n = 225), and had either parastomal hernias (36.0%, n = 95) or incisional hernias (28.0%, n = 74). Respondents described how their hernia affected sexual intimacy, either due to the dislike of their physical appearance, pain or the practicalities of their hernia getting in the way. They reported that their hernia restricted them from engaging in certain exercise activities, and a significant proportion also reported an impact on their diet. Conclusion: This study has identified that in addition to functional problems, living with a hernia can affect mental health as well as social and physical relationships. Existing hernia QoL tools are limited in the outcomes that they measure. Without a comprehensive hernia specific QoL tool, it remains difficult for a surgeon to accurately assess the impact that different treatment modalities may have on patients.
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  • 文章类型: Journal Article
    目的:相当比例的造口患者发生造口旁疝(PSH),由于定义和诊断方式的异质性,报告的发生率在5%至50%之间差异很大。这些患者中有75%的PSHs有症状,由于器具配件问题,对生活质量造成重大影响,泄漏,皮肤脱落和疼痛。它们还可能导致窒息和阻塞的紧急情况。缺乏如何选择患者进行手术干预或保守治疗的证据。在那些接受手术的人中,特定患者或PSH的最佳手术并不总是明确的,存在许多选择.这项研究的目的是评估个体患者的PSH治疗对其随后自我报告结果的影响,包括治疗成功和生活质量。
    方法:这是一项关于PSH治疗的前瞻性国际队列研究,包括手术和非手术干预。一个由临床医生和专科护士组成的全球网络将招募1000-1500名患者,并集中详细信息,他们的个人背景和PSH治疗,以及长达30天的短期结果。然后,患者将提供他们自己的结果数据,包括生活质量以及他们的治疗是否成功。通过一个安全的在线系统,在3、6和12个月。PROPHER将分两个阶段运行:内部试点阶段,至少有来自五个国家的10家医院,以及来自欧洲结肠直肠学会网络的多达200家医院的主要阶段。
    结论:这项研究将提供丰富的同期信息,这些信息将提高我们为患者提供咨询的能力,并促进为PSH患者选择适当和个性化的干预措施。
    OBJECTIVE: A significant proportion of stoma patients develop a parastomal hernia (PSH), with reported rates varying widely from 5% to 50% due to heterogeneity in the definition and mode of diagnosis. PSHs are symptomatic in 75% of these patients, causing a significant impact on quality of life due to issues with appliance fitting, leakage, skin excoriation and pain. They can also lead to emergency presentations with strangulation and obstruction. Evidence is lacking on how to select patients for surgical intervention or conservative treatment. In those who do undergo surgery, the best operation for a particular patient or PSH is not always clear and many options exist. The aim of this study is to assess the impact of an individual patient\'s PSH treatment on their subsequent self-reported outcomes including treatment success and quality of life.
    METHODS: This is a prospective international cohort study of PSH treatment, including both operative and non-operative interventions. A global network of clinicians and specialist nurses will recruit 1000-1500 patients and centralize detailed information, their individual background and their PSH treatment, as well as short-term outcomes up to 30 days. Patients will then provide their own outcomes data including quality of life and whether their treatment was successful, via a secure online system, at 3, 6 and 12 months. PROPHER will be run in two phases: an internal pilot phase of at least 10 hospitals from up to five countries, and a main phase of up to 200 hospitals from across the European Society of Coloproctology network.
    CONCLUSIONS: This study will provide a wealth of contemporaneous information which will improve our ability to counsel patients and facilitate improved selection of appropriate and personalized interventions for those with a PSH.
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  • 文章类型: Randomized Controlled Trial
    造口旁疝(PSH)是根治性膀胱切除术后接受回肠导管尿流改道的患者的常见并发症。在这项随机对照临床试验中,我们验证了我们之前的发现,即回肠导管腹膜外穿刺可降低PSH的发生率.总的来说,在中山大学肿瘤中心接受根治性膀胱切除术的104例连续患者随机分为1:1,分别接受改良(腹膜外)回肠导管(n=52)或常规回肠导管(n=52)。主要终点是随访期间放射性PSH的发生率。改良组放射性PSH的发生率低于常规组(11.5%vs.28.8%;p=0.028)中位随访32个月后,对应于改良导管组的风险比为0.374(95%置信区间:0.145-0.965,p=0.034).结果支持我们先前的发现,即回肠导管的腹膜外化可有效降低接受回肠导管改道的患者的PSH风险。
    Parastomal hernia (PSH) is a common complication in patients receiving ileal conduit urinary diversion after radical cystectomy. In this randomized controlled clinical trial, we validate our previous finding that extraperitonealization of ileal conduit decreases incidence of PSH. In total, 104 consecutive patients undergoing radical cystectomy at Sun Yat-sen University Cancer Center are randomized 1:1 to receive either modified (extraperitonealized) ileal conduit (n = 52) or conventional ileal conduit (n = 52). Primary endpoint is incidence of radiological PSH during follow-up. Incidence of radiological PSH is lower in the modified group than in the conventional group (11.5% vs. 28.8%; p = 0.028) after a median follow-up of 32 months, corresponding to a hazard ratio of 0.374 (95% confidence interval: 0.145-0.965, p = 0.034) in the modified conduit group. The results support our previous finding that extraperitonealization of the ileal conduit is effective for reducing risk of PSH in patients receiving ileal conduit diversion.
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  • 文章类型: Journal Article
    造口旁疝是造口手术的常见后果,可在多达50%的患者中发生。它们要么被保守地改造,通过支持袜子,或者手术。一项名为疝主动生活试验(HALT)的患者可行性研究旨在检查基于临床普拉提的锻炼计划是否为管理造口旁疝或隆起提供了替代方法。
    患有回肠造口术或结肠造口术的成年人被纳入研究。干预措施包括多达12次在线练习手册和与运动专家的视频。进行了访谈,以探讨参与者的干预经验。对访谈数据进行了系统和专题分析。参与者还被要求每周完成患者日记。
    完成干预的13名参与者中有12名同意接受采访。分析后,出现了三个主要主题,包括管理疝气/隆起,好处和障碍。与会者谈到了该计划的好处,包括:减少疝气的大小,加强腹部控制,身体自信和姿势,以及增加身体活动水平。所描述的障碍通常被克服,允许参与者参与被认为是积极的和可能改变生活的体验。
    针对造口旁疝患者的基于普拉提的临床锻炼计划可以直接和间接改善患者的疝管理,幸福感和日常生活。患有疝气的人应该被告知需要,和价值,锻炼以加强核心肌肉,作为他们自我管理的非手术选择的一部分。
    UNASSIGNED: Parastomal hernias are a common consequence of stoma surgery and can occur in up to 50% of patients. They are mangaged either conservatively, through support hosiery, or surgically. A patient feasibility study called the Hernia Active Living Trial (HALT) was designed to examine if a clinical pilates-based exercise programme offers an alternative approach to managing a parastomal hernia or bulge.
    UNASSIGNED: Adults with an ileostomy or colostomy who perceived they had a bulge around their stoma were included in the study. The intervention included up to 12 online sessions of an exercise booklet and videos with an exercise specialist. Interviews were conducted to explore participants\' experiences of the intervention. The interview data were analysed systematically and thematically. Participants were also asked to complete patient diaries every week.
    UNASSIGNED: Twelve of the 13 participants who completed the intervention agreed to be interviewed. Following analysis, three main themes emerged including managing a hernia/bulge, benefits and barriers. Participants talked about the benefits of this programme including: reduction of the size of their hernia, increased abdominal control, body confidence and posture, as well as increased physical activity levels. The barriers described were generally overcome allowing participants to engage in what was perceived to be a positive and potentially life-changing experience.
    UNASSIGNED: A clinical pilates-based exercise programme for people with a parastomal hernia can bring both direct and indirect improvements to a patient\'s hernia management, sense of wellbeing and day-to-day life. Individuals with a hernia should be informed about the need for, and value of, exercise to strengthen core muscles, as part of their non-surgical options for self-management.
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  • 文章类型: Journal Article
    研究通过扩大的(U-Plus)皮肤桥环回肠造口术进行标本提取的可行性和安全性。
    回顾性分析2018年8月至2022年8月行腹腔镜低位直肠前切除术+皮桥回肠造口术的95例直肠癌患者,其中经扩大(U-Plus)皮桥回肠造口术(实验组)44例,经腹部切口标本提取(对照组)51例。在应用倾向得分匹配(PSM)之后,34对数据成功匹配。随后,对两组患者的临床资料进行对比分析。
    实验组在各个方面均表现出比对照组明显更好的结果。具体来说,实验组的平均手术时间值较低(P<0.001),估计失血量(P<0.001),术后可见切口的中位长度(P<0.001),术后第一天的中位VAS疼痛评分(P=0.015),术后平均住院时间(P=0.001)。两组造口相关并发症发生率比较,差异无统计学意义(P>0.05)。在每一组中,造口闭合术前造口QOL评分明显高于术后1个月和2个月,具有统计学意义(P<0.05)。
    通过U-Plus皮桥回肠造口术进行标本提取是一种安全可行的方法,可缩短手术时间和术后视觉切口长度,减少估计的失血量,与通过腹部切口提取标本相比,减少了患者术后疼痛。
    UNASSIGNED: To investigate the feasibility and safety of specimen extraction via an enlarged (U-Plus) skin bridge loop ileostomy.
    UNASSIGNED: A retrospective analysis of 95 patients with rectal cancer who underwent laparoscopic low anterior rectal resection and skin bridge loop ileostomy between August 2018 and August 2022, including 44 patients with specimen extraction via an enlarged (U-Plus) skin bridge loop ileostomy (experimental group) and 51 patients with specimen extraction via an abdominal incision (control group). Following the application of propensity score matching (PSM), 34 pairs of data were successfully matched. Subsequently, a comparative analysis was conducted on the clinical data of the two groups.
    UNASSIGNED: The experimental group exhibited significantly better outcomes than the control group in various aspects. Specifically, the experimental group had lower values for average operative time (P < 0.001), estimated blood loss (P < 0.001), median length of visible incision after surgery (P < 0.001), median VAS pain score on the first day after surgery (P = 0.015), and average postoperative hospitalization (P = 0.001). There was no statistical significance observed in the incidence of stoma-related complications in both groups (P > 0.05). Within each group, the stoma-QOL scores before stoma closure surgery were significantly higher than those at one month and two months after the surgery, with statistical significance (P < 0.05).
    UNASSIGNED: Specimen extraction via a U-Plus skin bridge loop ileostomy is a safe and feasible method that shortens operation time and postoperative visual incision length, decreases estimated blood loss, and reduces patient postoperative pain compared with specimen extraction via an abdominal incision.
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