Norway

挪威
  • 文章类型: Journal Article
    背景:基本运动技能(FMS)和身体素质(FIT)在儿童发育中起着重要作用,并为终身参与体育锻炼(PA)提供了基础。不幸的是,许多孩子的PA水平欠佳,FMS,和FIT。主动学习挪威学前(er)(ACTNOW)研究调查了工作人员主导的PA干预对FMS的影响,FIT,和3-5岁儿童的PA。
    方法:邀请了挪威西部有6名3-4岁儿童的幼儿园(n=56)。其中,46人同意参与,并被分组随机纳入干预措施(n=23所幼儿园[381名儿童,3.8年。,55%男孩])或对照组(n=23[438,3.7岁。,52%男孩])。干预性幼儿园参加了为期18个月的PA干预,涉及2019年至2022年间7个月的员工专业发展,总计50小时,包括面对面的研讨会,网络研讨会,数字讲座ACTNOW的主要结果是认知变量,而这项研究调查了对次要结局的影响。FMS通过涵盖运动的9个项目进行测量,对象控件,和平衡技能。FIT被评估为运动适应性(4×10穿梭跑测试)和上下肌肉力量(握力和站立跳远)。用加速度计(ActiGraphGT3X+)测量PA。所有措施都在基线进行,7-,18个月的随访。使用重复测量的线性混合模型分析了效果,其中儿童和学龄前儿童作为随机效应,并调整了基线得分。
    结果:干预性幼儿园的参与者表现为阳性,与对照组相比,7个月时的对象控制技能(标准化效应大小(ES)=0.17)和18个月时的运动技能(ES=0.21)具有显着影响。7个月时,握力强度(ES=-0.16)有负面影响。没有发现平衡技能的影响,站立跳远,或运动健身。在学龄前,久坐时间减少(ES=-0.18),轻度(ES=0.14)和中度至重度PA(ES=0.16)在7个月时增加,而轻度PA在18个月时下降(ES=-0.15),干预与控制。对于其他强度或全天PA没有发现影响。
    结论:ACTNOW干预改善了一些FMS结局,并在短期内增加了PA。需要进一步的研究来调查如何提高工作人员主导的PA干预措施的有效性,并实现儿童PA的可持续改善,FMS,和FIT。
    背景:Clinicaltrials.gov,标识符NCT04048967,2019年8月7日注册。
    背景:ACTNOW得到了挪威研究委员会的支持(授权号287903),SognOgFjordane县长,SparebankenSognOgFjordane基金会,和西挪威应用科学大学。
    BACKGROUND: Fundamental motor skills (FMS) and physical fitness (FIT) play important roles in child development and provide a foundation for lifelong participation in physical activity (PA). Unfortunately, many children have suboptimal levels of PA, FMS, and FIT. The Active Learning Norwegian Preschool(er)s (ACTNOW) study investigated the effects of a staff-led PA intervention on FMS, FIT, and PA in 3-5-year-old children.
    METHODS: Preschools in Western Norway having ≥ six 3-4-year-old children were invited (n = 56). Of these, 46 agreed to participate and were cluster-randomized into an intervention (n = 23 preschools [381 children, 3.8 yrs., 55% boys]) or a control group (n = 23 [438, 3.7 yrs., 52% boys]). Intervention preschools participated in an 18-month PA intervention involving a 7-month staff professional development between 2019 and 2022, amounting to 50 h, including face-to-face seminars, webinars, and digital lectures. Primary outcomes in ACTNOW were cognition variables, whereas this study investigated effects on secondary outcomes. FMS was measured through 9 items covering locomotor, object control, and balance skills. FIT was assessed as motor fitness (4 × 10 shuttle-run test) and upper and lower muscular strength (handgrip and standing long jump). PA was measured with accelerometers (ActiGraph GT3X +). All measures took place at baseline, 7-, and 18-month follow-up. Effects were analysed using a repeated measures linear mixed model with child and preschool as random effects and with adjustment for baseline scores.
    RESULTS: Participants in the intervention preschools showed positive, significant effects for object control skills at 7 months (standardized effect size (ES) = 0.17) and locomotor skills at 18 months (ES = 0.21) relative to controls. A negative effect was found for handgrip strength (ES = -0.16) at 7 months. No effects were found for balance skills, standing long jump, or motor fitness. During preschool hours, sedentary time decreased (ES = -0.18), and light (ES = 0.14) and moderate-to-vigorous PA (ES = 0.16) increased at 7 months, whereas light PA decreased at 18 months (ES = -0.15), for intervention vs control. No effects were found for other intensities or full day PA.
    CONCLUSIONS: The ACTNOW intervention improved some FMS outcomes and increased PA short-term. Further research is needed to investigate how to improve effectiveness of staff-led PA interventions and achieve sustainable improvements in children\'s PA, FMS, and FIT.
    BACKGROUND: Clinicaltrials.gov, identifier NCT04048967 , registered August 7, 2019.
    BACKGROUND: ACTNOW was supported by the Research Council of Norway (grant number 287903), the County Governor of Sogn og Fjordane, the Sparebanken Sogn og Fjordane Foundation, and the Western Norway University of Applied Sciences.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    在从青春期到成年的挪威青年队列中,从16年到27年,股骨颈和全髋关节的骨矿物质密度(BMD)水平下降,但在全身继续增加,表明特定部位达到了峰值骨量。
    目的:研究挪威青少年成年期骨密度(BMD)水平的纵向趋势。
    方法:在前瞻性队列设计中,我们跟踪了980名16-19岁的青少年(473(48%)女性)到成年(26-29岁)三次:2010-2011(FitFutures1(FF1)),2012-2013(FF2),和2021-2022(FF3),测量股骨颈的BMD(g/cm2),全髋关节,和全身双X射线吸收法(DXA)。我们使用线性混合模型来检查从FF1到FF3的纵向BMD变化。
    结果:从中位年龄16岁(FF1)开始,女性股骨颈BMD(平均g/cm2(95%CI))在中位年龄18岁(FF2)时从1.070(1.059-1.082)略微增加至1.076(1.065-1.088,p=0.015),但在中位年龄27岁(FF3)时下降至1.041(1.029-1.053,p<0.001).在男性中观察到类似的模式:16岁,1.104(1.091-1.116);27年,1.063(1.050-1.077,p<0.001);对于两种性别的全髋关节(均p<0.001)。男女的总身体BMD从16岁增加到27岁(女性:16岁,1.141(1.133-1.148);27年,1.204(1.196-1.212),p<0.001;男性:16岁,1.179(1.170-1.188);27年,1.310(1.296-1.315),p<0.001)。
    结论:年轻的挪威女性和男性的股骨和全髋关节部位的BMD水平从16岁增加到18岁,在对参与者进行长达27年的随访时,在股骨部位观察到小幅下降。从青春期到成年,全身BMD持续增加。
    In a Norwegian youth cohort followed from adolescence to young adulthood, bone mineral density (BMD) levels declined at the femoral neck and total hip from 16 to 27 years but continued to increase at the total body indicating a site-specific attainment of peak bone mass.
    OBJECTIVE: To examine longitudinal trends in bone mineral density (BMD) levels in Norwegian adolescents into young adulthood.
    METHODS: In a prospective cohort design, we followed 980 adolescents (473 (48%) females) aged 16-19 years into adulthood (age of 26-29) on three occasions: 2010-2011 (Fit Futures 1 (FF1)), 2012-2013 (FF2), and 2021-2022 (FF3), measuring BMD (g/cm2) at the femoral neck, total hip, and total body with dual x-ray absorptiometry (DXA). We used linear mixed models to examine longitudinal BMD changes from FF1 to FF3.
    RESULTS: From the median age of 16 years (FF1), femoral neck BMD (mean g/cm2 (95% CI)) slightly increased in females from 1.070 (1.059-1.082) to 1.076 (1.065-1.088, p = 0.015) at the median age of 18 years (FF2) but declined to 1.041 (1.029-1.053, p < 0.001) at the median age of 27 years (FF3). Similar patterns were observed in males: 16 years, 1.104 (1.091-1.116); 27 years, 1.063 (1.050-1.077, p < 0.001); and for the total hip in both sexes (both p < 0.001). Total body BMD increased from age 16 to 27 years in both sexes (females: 16 years, 1.141 (1.133-1.148); 27 years, 1.204 (1.196-1.212), p < 0.001; males: 16 years, 1.179 (1.170-1.188); 27 years, 1.310 (1.296-1.315), p < 0.001).
    CONCLUSIONS: BMD levels increased from 16 to 18 years at the femoral and total hip sites in young Norwegian females and males, and a small decline was observed at the femoral sites when the participants were followed up to 27 years. Total body BMD continued to increase from adolescence to young adulthood.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:救护车服务背景下的团队合作表现出独特的特征,因为这种环境涉及一个小的核心团队,必须适应一个动态的团队结构,包括医疗保健专业人员和紧急服务。必须更深入地了解救护车团队的运作方式。因此,这项研究旨在探讨救护车专业人员团队合作的经验,以及团队培训计划的实施对他们的影响。
    方法:进行了一项定性的描述性研究,其中包括参加焦点小组访谈的救护车专业人员,他们在挪威一家医院信托基金的7个救护车站实施团队培训计划之前和之后进行。使用基于演绎归纳法的反身主题分析对数据进行了分析。
    结果:我们的分析揭示了15个子主题,这些主题是救护车专业人员在团队合作和团队培训计划方面的经验,根据团队结构的五个主要主题组织,通信,领导力,形势监测,和相互支持。救护车专业人员的经验范围从团队组成,人际关系和专业关系的重要性到他们对不同沟通方式的偏好以及救护车服务中团队领导的必要性。团队培训计划提高了团队合作意识,而团队合作工具的采用受到个人和环境因素的影响。简介/身份,Situation,背景,评估和建议(ISBAR)通信工具由于其易用性而被认为是该计划最有益的方面,这导致协商和信息移交的结构和质量得到改善。
    结论:这项研究记录了救护车专业人员团队合作的不同特征和偏好,强调在这方面熟练的伙伴关系的特别重要性。参加团队培训计划被认为是对团队合作重要性的宝贵提醒,从而为提高沟通技能提供了基础。
    背景:ClinicalTrials.gov-ID:NCT05244928。
    BACKGROUND: Teamwork in the context of ambulance services exhibits unique characteristics, as this environment involves a small core team that must adapt to a dynamic team structure that involves health care professionals and emergency services. It is essential to acquire a deeper understanding of how ambulance teams operate. Therefore, this study aimed to explore the experiences of ambulance professionals with teamwork and how they were influenced by the implementation of a team training programme.
    METHODS: A qualitative descriptive study was conducted involving ambulance professionals who took part in focus group interviews carried out both before and after the implementation of a team training program across seven ambulance stations within a Norwegian hospital trust. The data were analysed using reflexive thematic analysis based on a deductive-inductive approach.
    RESULTS: Our analysis revealed 15 subthemes that characterised ambulance professionals\' experiences with teamwork and a team training programme, which were organised according to the five main themes of team structure, communication, leadership, situation monitoring, and mutual support. Ambulance professionals\' experiences ranged from the significance of team composition and interpersonal and professional relationships to their preferences regarding different communication styles and the necessity of team leaders within the ambulance service. The team training programme raised awareness of teamwork, while the adoption of teamwork tools was influenced by both individual and contextual factors. The Introduction/Identity, Situation, Background, Assessment and Recommendation (ISBAR) communication tool was identified as the most beneficial aspect of the programme due to its ease of use, which led to improvements in the structure and quality of consultations and information handover.
    CONCLUSIONS: This study documented the diverse characteristics and preferences associated with teamwork among ambulance professionals, emphasising the particular importance of proficient partnerships in this context. Participation in a team training programme was perceived as a valuable reminder of the significance of teamwork, thus providing a foundation for the enhancement of communication skills.
    BACKGROUND: ClinicalTrials.gov-ID: NCT05244928.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:公共卫生与工作生活密切相关。尽管挪威是世界上最平等的国家之一,工作生活仍然是按性别划分的。女性在工作生活中的参与率低于男性,他们兼职工作更多,缺病率更高。研究主要集中在性别差异的结构和文化原因上,而不是事实上,女性和男性有不同的生物学和面临不同的健康挑战。该项目的目的是探索妇女健康与女性参与工作生活之间的经验关联。
    方法:选择定性方法来调查女性的经历。我们对11名女高中教师进行了深入采访,并通过一个焦点小组补充了材料,该小组有来自同一组织的五名经理。访谈被逐字记录和转录。为了分析过程的一致性,我们使用了反身主题分析的六个步骤。
    结果:老师们分享了妇女健康领域中的各种经验丰富的健康问题和工作环境中的障碍。确定了四个主要主题:(1)工作中妇女健康的隐形,(2)工作中妇女健康的复杂性和缺乏认识,(3)工作环境中的女性健康和(4)女性健康与角色冲突。两个线人之间几乎没有矛盾。我们发现健康,工作和总生活交织在一起,这种复杂性,缺乏对女性健康的认识和不可见性在不同层面上出现了一种相互影响:对于女性自身,在组织和社会中。
    结论:在工作环境中缺乏对妇女健康的认识和忽视,这表明会影响妇女的工作参与。女性健康的复杂性并没有被工作环境中旨在保护和促进员工职业健康的性别中立结构所体现。因此,在工作环境中承认妇女的健康可以促进性别平等,促进健康和可持续的工作生活。
    BACKGROUND: Public health and working life are closely related. Even though Norway is one of the world\'s most equality-oriented countries, working life is still divided by gender. Women have a lower rate of participation in working life than men, they work more part-time and they have a higher sickness absence. Research has mostly focused on structural and cultural reasons for gender differences, rather than on the fact that women and men have different biology and face different health challenges. The aim of this project was to explore experienced associations between women\'s health and female participation in working life.
    METHODS: Qualitative methods were chosen for investigating women\'s experiences. We carried out in-depth interviews with 11 female high school teachers and supplemented the material with a focus group with five managers from the same organisation. The interviews were recorded and transcribed verbatim. We used the six steps of reflexive thematic analysis for consistency in the analysis process.
    RESULTS: The teachers shared a variety of experienced health issues within the field of women\'s health and perceived barriers in the work environment. Four main themes were identified: (1) invisibility of women\'s health at work, (2) complexity and lack of recognition of women\'s health at work, (3) women\'s health in work environment and (4) women\'s health and role conflicts. There were few contradictions between the two informant groups. We found that health, work and total life intertwine and that complexity, lack of recognition and invisibility of women\'s health appear at different levels in a mutual influence: for the women themselves, in the organisation and in society.
    CONCLUSIONS: Lack of recognition and invisibility of women\'s health in the work environment is suggested to influence women\'s work participation. The complexity of female health is not captured by gender-neutral structures in the work environment meant to protect and promote employees\' occupational health. Recognition of women\'s health in the work context can therefore contribute to a gender-equal, health-promoting and sustainable working life.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:过量是释放出狱人员死亡的主要原因,阿片类药物激动剂治疗与监禁后死亡率的降低有关。然而,很少有研究探讨监狱释放后死亡的潜在可改变的危险因素和保护因素之间的相互作用.我们旨在描述2000-22年间从挪威监狱释放的个体的全因死亡率和过量死亡率,并确定这些个体中与这两种类型的死亡率相关的预先存在的风险因素6个月。
    方法:对于本前瞻性分析,我们使用了挪威监狱释放研究(nPRIS)的数据,其中包括2000年1月1日至2022年12月31日在挪威监狱中的所有人;挪威死因登记处;挪威监狱登记处;挪威患者登记处;和挪威统计局。挪威在此期间开放的所有监狱都包括在内。没有挪威个人身份号码或在监狱以外服刑的人被排除在这一分析之外。确定与从监狱释放的人的全因死亡和过量死亡相关的预先存在的风险因素,我们在2010年1月1日对观察期进行了保留,创建了一个个体子样本.我们将粗死亡率(CMR)和相应的95%CI计算为发布后几个时间段内每10万人年的死亡人数。主要结果是根据ICD-10的全因死亡率和过量死亡率,在所有参与者中进行评估,并通过两个独立的Cox比例风险模型进行分析。
    结果:nPRIS队列包括2000年至2022年在挪威从监狱释放的112877人,其中11995人(10·6%)为女性,100865人(89·4%)为男性。在1463035人年期间,我们确定了13004例全因死亡率和3085例超剂量死亡率。全因死亡率的估计CMR为889(95%CI874-904)/10万人年,过量死亡率为211(203-218)/10万人年。在2010-22年期间进入监狱前被诊断患有阿片类药物使用障碍的人中(n=6830),估计提供阿片类药物激动剂治疗与降低全因死亡率(危险比0·58,95%CI0·39-0·85)和过量死亡率(0·51,0·31-0·82)在调整社会人口统计学后离开监狱后的6个月内,与监狱有关,和临床特征。
    结论:从挪威监狱释放的被诊断患有阿片类药物使用障碍的人,在监狱中提供的阿片类药物激动剂治疗是6个月时全因死亡率和过量死亡率的保护因素。在监狱中提供阿片类药物激动剂治疗对于降低释放后6个月的死亡率至关重要,并且应该向所有有治疗需求的监狱中的人提供。
    背景:挪威东南部地区卫生局和挪威研究委员会。
    BACKGROUND: Overdose is the leading cause of death for people released from prison, and opioid agonist treatment is associated with reductions in mortality after imprisonment. However, few studies have explored the interplay of the potential modifiable risk factors and protective factors for mortality after release from prison. We aimed to describe all-cause mortality and overdose mortality among individuals released from Norwegian prisons during 2000-22 and to identify pre-existing risk factors associated with both types of mortality among these individuals for 6 months.
    METHODS: For this prospective analysis, we used data from the Norwegian Prison Release Study (nPRIS), which includes all people in prison in Norway between Jan 1, 2000, and Dec 31, 2022; the Norwegian Cause of Death Registry; the Norwegian Prison Registry; the Norwegian Patient Registry; and Statistics Norway. All prisons in Norway that were open during this period were included. People who did not have a Norwegian personal identification number or were serving their sentence outside of prison units were excluded from this analysis. To identify pre-existing risk factors associated with all-cause and overdose mortality among people released from prison, we left-censored the observation period on Jan 1, 2010, creating a subsample of individuals. We calculated crude mortality rates (CMRs) and corresponding 95% CIs as the number of deaths per 100 000 person-years for several time periods after release. The primary outcomes were all-cause mortality and overdose mortality according to the ICD-10, assessed in all participants and analysed via two separate Cox proportional-hazards models.
    RESULTS: The total nPRIS cohort included 112 877 individuals released from prison in Norway between 2000 and 2022, 11 995 (10·6%) of whom were female and 100 865 (89·4%) of whom were male. We identified 13 004 instances of all-cause mortality and 3085 instances of overdose mortality during the 1 463 035 person-years. The estimated CMR for all-cause mortality was 889 (95% CI 874-904) per 100 000 person-years and for overdose mortality was 211 (203-218) per 100 000 person-years. Among people diagnosed with opioid use disorder before entering prison during 2010-22 (n=6830), provision of opioid agonist treatment was estimated to be associated with reductions in both all-cause mortality (hazard ratio 0·58, 95% CI 0·39-0·85) and overdose mortality (0·51, 0·31-0·82) in the 6 months after leaving prison after adjustment for sociodemographic, prison-related, and clinical characteristics.
    CONCLUSIONS: In people diagnosed with opioid use disorder released from Norwegian prisons, opioid agonist treatment provided while in prison was a protective factor for both all-cause and overdose mortality at 6 months. Provision of opioid agonist treatment while in prison is crucial in reducing mortality for 6 months after release and should be available to all people in prison who have treatment needs.
    BACKGROUND: South-Eastern Norway Regional Health Authority and the Research Council of Norway.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    目的:乳腺癌治疗可能会干扰工作能力。以前的复工研究通常集中在治疗完成后被邀请参加的参与者。参与多种多样,导致潜在的选择偏差。这是一项基于健康记录的研究,评估数据的完整性,在基线和诊断后一年.还分析了基线变量与返回工作之间的相关性。
    方法:这是一项对2019年至2022年在诺德兰县接受治疗的150名无复发幸存者的回顾性研究(所有患者均采用不同类型的全身治疗和手术进行管理)。在区域电子病历(EPR)中评估工作状态。采用65岁的截止年龄来定义两个亚组。
    结果:在诊断时,所有150例患者的职业状况均可评估.几乎所有65岁以上的患者都已退休(79%)或因先前诊断的疾病而领取残疾养恤金(19%)。诊断后一年的数据完整性不完善,因为EPR不包含19名幸存者的必要信息。大多数在诊断时≤65岁的人重返工作岗位。88例患者中只有14例(16%)没有重返工作岗位。术后淋巴结分期是唯一有意义的预测因素。pN1-3的患者的回报率低于节点阶段较低的患者(68%)。
    结论:这项试点研究强调了挪威农村地区基于EPR的研究的实用性和局限性,强调需要全面,支持乳腺癌幸存者重返工作岗位的个性化干预措施。研究结果强调了考虑不同社会人口统计学和临床因素的重要性,以及长期的潜在好处,以人群为基础的研究,以解决这些复杂的挑战。
    OBJECTIVE: Breast cancer treatment may interfere with work ability. Previous return-to-work studies have often focused on participants who were invited to participate after treatment completion. Participation varied, resulting in potential selection bias. This is a health-record-based study evaluating data completeness, both at baseline and one year after diagnosis. Correlations between baseline variables and return to work were also analyzed.
    METHODS: This is a retrospective review of 150 relapse-free survivors treated in Nordland county between 2019 and 2022 (all-comers managed with different types of systemic treatment and surgery). Work status was assessed in the regional electronic patient record (EPR). A 65-years age cut-off was employed to define two subgroups.
    RESULTS: At diagnosis, occupational status was assessable in all 150 patients. Almost all patients older than 65 years of age were retired (79%) or on disability pension for previously diagnosed conditions (19%). Data completeness one year after diagnosis was imperfect, because the EPR did not contain required information in 19 survivors. The majority of those ≤65 years of age at diagnosis returned to work. Only 14 of 88 patients (16%) did not return to work. Postoperative nodal stage was the only significant predictive factor. Those with pN1-3 had a lower return rate (68%) than their counterparts with lower nodal stage.
    CONCLUSIONS: This pilot study highlights the utility and limitations of EPR-based research in a rural Norwegian setting, emphasizing the need for comprehensive, individualized interventions to support breast cancer survivors in returning to work. The findings underscore the importance of considering diverse sociodemographic and clinical factors, as well as the potential benefits of long-term, population-based studies to address these complex challenges.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    目的:观察性研究表明,在各种运动中,职业运动员的肌萎缩侧索硬化症(ALS)风险增加。对于适度增加的身体活动和健身水平,结果大相径庭。通过一项队列研究,我们旨在评估体力活动和体能指标(自我报告的体力活动和静息心率)与长期ALS风险之间的关系.
    方法:来自挪威大型心血管健康调查(1985-1999),我们收集了有关休闲时间自我报告的体育锻炼的信息,静息心率,和其他心血管危险因素。ALS患者是通过覆盖整个人群的健康登记来确定的。我们使用Cox比例风险模型,根据自我报告的3类体力活动水平评估ALS的风险(1:久坐;2:每周最少4小时步行或骑自行车;3:每周最少4小时休闲运动或艰苦训练)。静息心率在连续尺度和分布的四分位数上建模。
    结果:在373,696名研究参与者中(纳入时平均40.9[SD1.1]年),504(41.2%的女性)在平均27.2(SD5.0)年的随访时间内发展为ALS。与体力活动水平最低的参与者相比,最高水平的风险比为0.71(95%CI0.53-0.95).在总样本中静息心率和ALS之间没有明显的关联。在男人中,ALS的风险比为0.71(95%CI0.53-0.95),对于那些报告中等体力活动水平的患者,ALS的风险比为0.59(95%CI0.42-0.84),与那些报告低水平的人相比。与第二高四分位数的男性相比,静息心率在最低四分位数的男性的ALS风险降低了32%(风险比0.68,95%CI0.49-0.94)。在女性中,未检测到自我报告的体力活动水平和静息心率与ALS风险之间存在关联.
    结论:高水平的体力活动和健康指标与男性30多年后的ALS风险降低相关,但不是女人。
    OBJECTIVE: Observational studies have demonstrated an increased amyotrophic lateral sclerosis (ALS) risk among professional athletes in various sports. For moderately increased levels of physical activity and fitness, the results are diverging. Through a cohort study, we aimed to assess the relationship between indicators of physical activity and fitness (self-reported physical activity and resting heart rate) and long-term ALS risk.
    METHODS: From a large Norwegian cardiovascular health survey (1985-1999), we collected information on self-reported physical activity in leisure time, resting heart rate, and other cardiovascular risk factors. Patients with ALS were identified through health registries covering the whole population. We fitted Cox proportional hazard models to assess the risk of ALS according to levels of self-reported physical activity in 3 categories (1: sedentary; 2: minimum 4 hours per week of walking or cycling; 3: minimum 4 hours per week of recreational sports or hard training), and resting heart rate modeled both on the continuous scale and as quartiles of distribution.
    RESULTS: Out of 373,696 study participants (mean 40.9 [SD 1.1] years at inclusion), 504 (41.2% women) developed ALS during a mean follow-up time of 27.2 (SD 5.0) years. Compared with participants with the lowest level of physical activity, the hazard ratio was 0.71 (95% CI 0.53-0.95) for those with the highest level. There were no clear associations between resting heart rate and ALS in the total sample. In men, the hazard ratio of ALS was 0.71 (95% CI 0.53-0.95) for those reporting moderate levels of physical activity and 0.59 (95% CI 0.42-0.84) for those reporting high levels, compared with those reporting low levels. Men with resting heart rate in the lowest quartile had 32% reduced risk of ALS (hazard ratio 0.68, 95% CI 0.49-0.94) compared with those in the second highest quartile. In women, no association was detected between neither self-reported levels of physical activity nor resting heart rate and ALS risk.
    CONCLUSIONS: Indicators of high levels of physical activity and fitness are associated with a reduced risk of ALS more than 30 years later in men, but not in women.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    背景:提前护理计划是促进与患者就未来医疗保健进行对话的一种方式,值,和生命结束时的偏好。疗养院医生有医疗责任和主要义务,以促进与患者的计划会议。尽管在挪威的疗养院中已经非常注重建立预先护理计划,它尚未得到广泛实施。陈述的原因是疗养院的工作例程不包括此类会议,或者由于患者虚弱,实施似乎很复杂。因此,这项研究的目的是探索医生如何理解和体验挪威疗养院的预先护理计划和后续护理计划。
    方法:该研究采用现象学诠释学方法进行了定性研究设计,该方法基于对12位在社区护理中工作的疗养院医生的访谈。面试于2023年2月至2023年5月进行,使用半结构化面试指南。所有采访都记录在音频文件上,转录,并使用结构文本分析进行分析。
    结果:研究结果基于以下主题提出:(1)预先护理计划是一个对话和过程,(2)提前护理计划意味着澄清双方的期望,(3)为患者带来救济和希望的预先护理计划是一种医学艺术。
    结论:提前护理计划是一个复杂而动态的过程,意味着医疗,关于治疗水平的决定,疼痛缓解,并制定患者的自决和个人价值观得到尊重的护理计划。这意味着医生之间正在进行的对话,病人,和他们的亲戚关于尊严等价值观,自我理解,社会关系,和生命终结时的存在问题。提前护理计划需要一个整体的方法,以满足患者的心理和生存需求,如舒适,信任,希望,和尊重以及他们的喜好和关注。
    BACKGROUND: Advance care planning is a way of facilitating conversations with patients about future health care, values, and preferences at end of life. Nursing home physicians have the medical responsibility and the main obligation to facilitate planned meetings with patients. Although there has been a great deal of focus on establishing advance care planning in Norwegian nursing homes, it has yet to be widely implemented. Stated reasons are that the work routines in a nursing home do not include such meetings or that implementation seems complex due to frail patients. The aim of this study is thus to explore how physicians understand and experience advance care planning and follow-up of care plans in Norwegian nursing homes.
    METHODS: The study has a qualitative research design with a phenomenological-hermeneutic approach based on interviews of twelve nursing home physicians working in community care. Interviews were conducted in February 2023 to May 2023, using a semi-structured interview guide. All interviews were recorded on audio files, transcribed, and analyzed using structural text analysis.
    RESULTS: The findings are presented based on the following themes: (1) advance care planning is a dialog and a process, (2) advance care planning implies clarifying mutual expectations, and (3) advance care planning that brings relief and hope to patients is a medical art.
    CONCLUSIONS: Advance care planning is a complex and dynamic process that implies medical treatment, decisions on treatment level, pain relief, and formulation of care plans where the patient\'s self-determination and personal values are respected. It implies an ongoing dialogue between physicians, patients, and their relatives about values such as dignity, self-understanding, social relations, and existential questions at end of life. Advance care planning requires a holistic approach that meets patients\' psychological and existential needs such as comfort, trust, hope, and respect as well as their preferences and concerns.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    有限的研究已经对血清25-羟维生素D[25(OH)D]水平与收缩压(SBP)之间的关系进行了三角测量,舒张压(DBP)或高血压风险利用观察和孟德尔随机化(MR)方法。我们使用来自挪威Trøndelag健康研究(HUNT)的数据进行横断面(n=5854)和前瞻性(n=3592)分析,以及单样本MR(n=86,324)。我们还使用了两个样本MR的最大公开可用数据。我们的横截面分析显示25nmol/L的25(OH)D增加与SBP的1.73mmHg下降相关(95%CI-2.46至-1.01),校正重要混杂因素后,DBP降低0.91mmHg(95%CI-1.35~-0.47),高血压患病率降低19%(OR0.81,95%CI0.74~0.90).然而,这些关联在前瞻性分析中消失了.单样本和双样本MR结果进一步表明,普通人群中血清维生素D水平与血压或高血压风险之间没有因果关系。
    Limited studies have triangulated the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels and systolic blood pressure (SBP), diastolic blood pressure (DBP) or hypertension risk utilizing both observational and Mendelian randomization (MR) approaches. We employed data from the Norwegian Trøndelag Health Study (HUNT) to conduct cross-sectional (n = 5854) and prospective (n = 3592) analyses, as well as one-sample MR (n = 86,324). We also used largest publicly available data for two-sample MR. Our cross-sectional analyses showed a 25 nmol/L increase in 25(OH)D was associated with a 1.73 mmHg decrease in SBP (95% CI - 2.46 to - 1.01), a 0.91 mmHg decrease in DBP (95% CI - 1.35 to - 0.47) and 19% lower prevalence of hypertension (OR 0.81, 95% CI 0.74 to 0.90) after adjusting for important confounders. However, these associations disappeared in prospective analyses. One-sample and two-sample MR results further suggested no causal relationship between serum vitamin D levels and blood pressure or hypertension risk in the general population.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    我们探讨了家庭护理人员如何看待有关养老院居民护理的决策。
    这项定性研究使用了Flemming\'sGadamerian-based研究方法。对13名家庭成员(9名妇女,四名男子)三个挪威疗养院的居民。
    出现了以下主题:过度关注自治威胁居民的福祉和安全。居民的福祉是照顾者的责任。居民福祉是指导原则。
    居民的家庭成员和疗养院的看护人不同意维护居民自主权对尊重居民尊严的重要性。家庭成员认为,并非所有居民拒绝护理的情况都反映了自治情况,因为拒绝护理通常并不反映居民的真实价值观和标准,源于障碍,使必要的护理行动变得困难。在居民拒绝基本护理或拒绝与居民二阶值不符的情况下,家庭成员建议照顾者努力了解拒绝的原因,并寻求非强制性的方式来解决它。因此,家庭成员似乎赞同在养老院中使用软家长制来维护居民的福祉和尊严。
    UNASSIGNED: We explored how family caregivers perceive decision-making regarding the care of nursing home residents.
    UNASSIGNED: This qualitative study used Flemming\'s Gadamerian-based research method. In person semi-structured interviews about decision-making concerning residents\' care were conducted with 13 family members (nine women, four men) of residents of three Norwegian nursing homes.
    UNASSIGNED: The following themes emerged: Excessive focus on autonomy threatens resident wellbeing and safety. Resident wellbeing is the caregiver\'s responsibility. Resident wellbeing serves as a guiding principle.
    UNASSIGNED: The family members of residents and the nursing home caregivers disagreed about the significance of upholding resident autonomy to respect residents\' dignity. The family members held that not all instances where residents refused care reflect autonomy situations as care refusal often does not reflect the resident\'s true values and standards but rather, stems from barriers that render necessary care actions difficult. In situations where residents refuse essential care or when the refusal does not align with the residents second-order values, the family members suggested that caregivers strive to understand the causes of refusal and seek non-coercive ways to navigate it. Hence, the family members seemed to endorse the use of soft paternalism in nursing homes to safeguard residents\' wellbeing and dignity.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

公众号