Norway

挪威
  • 文章类型: Journal Article
    目的:本研究旨在探讨手臂抬高与颈/肩痛之间的关系。以及家庭护理人员的躯干向前弯曲和腰痛。
    方法:来自特隆赫姆11个家庭护理单位的家庭护理工作者(N=116),挪威,填写疼痛评估和工作时间问卷,并连续7天佩戴3个加速度计。工作时间被划分成直立的尴尬姿势,不尴尬的姿势,和非直立的时间,即坐着。在组成方法框架内,姿势时间组成以对数比坐标表示,用于统计分析和建模.采用泊松广义线性混合模型分析直立体位上臂抬高与颈肩痛的关系,在直立姿势的躯干向前弯曲和腰痛之间,分别。使用等时替代分析来研究疼痛评估与在不同姿势中花费的时间的重新分配之间的关联。
    结果:在尴尬姿势中花费的时间很少,特别是对于更极端的角度(60°和90°)。调整年龄,性别,和身体质量指数,我们的研究表明,家庭护理人员在尴尬姿势中花费的时间组成与疼痛评估显着相关(P<0.01)。等时替代分析表明,从直立姿势重新分配5分钟,手臂升高到60°和90°以上,颈/肩痛评分增加6.8%和19.9%,分别。从直立下方到30°以上的前弯姿势重新分配5min,60°,90°与1.8%相关,3.5%,下腰痛增加4.0%,分别。
    结论:尽管暴露于尴尬的姿势是适度的,我们的结果显示,在家庭护理工作者中,在尴尬姿势中花费的时间增加与颈部/肩部疼痛和腰背痛的增加之间存在关联.由于肌肉骨骼疼痛是疾病缺席的主要原因,这些发现表明,家庭护理单位可以从重新组织工作中受益,以避免工人手臂过度抬高和躯干向前弯曲。
    OBJECTIVE: This study aimed to explore the association between arm elevation and neck/shoulder pain, and trunk forwarding bending and low back pain among home care workers.
    METHODS: Home care workers (N = 116) from 11 home care units in Trondheim, Norway, filled in pain assessment and working hours questionnaire, and wore 3 accelerometers for up to 7 consecutive days. Work time was partitioned into upright awkward posture, nonawkward posture, and nonupright time, i.e. sitting. Within a compositional approach framework, posture time compositions were expressed in terms of log-ratio coordinates for statistical analysis and modeling. Poisson generalized linear mixed models were used to analyze the relationship between arm elevation in upright postures and neck/shoulder pain, and between trunk forward bending in upright postures and low back pain, respectively. Isotemporal substitution analysis was used to investigate the association of pain assessment with the reallocation of time spent in the different postures.
    RESULTS: Time spent in awkward postures was modest, especially for the more extreme angles (60° and 90°). Adjusting for age, gender, and body mass index, our study suggested that the compositions of time spent by home care workers in awkward postures were significantly associated with pain assessment (P < 0.01). Isotemporal substitution analysis showed that reallocating 5 min from upright posture with arms elevated below to above 60° and 90° was associated with a 6.8% and 19.9% increase in the neck/shoulder pain score, respectively. Reallocating 5 min from a forward bending posture while upright below to above 30°, 60°, and 90° was associated with 1.8%, 3.5%, and 4.0% increase in low back pain, respectively.
    CONCLUSIONS: Although the exposure to awkward postures was modest, our results showed an association between increased time spent in awkward postures and an increase in neck/shoulder pain and low back pain in home care workers. As musculoskeletal pain is the leading cause of sickness absence, these findings suggest that home care units could benefit from re-organizing work to avoid excessive arm elevation and trunk forward bending in workers.
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  • 文章类型: Journal Article
    古档案对于我们了解物种对气候变暖的反应至关重要,然而,这样的档案在北极极为罕见。这里,我们结合了形态学分析和骨块骨编码,以研究挪威高纬度Storsteinhola洞穴系统(68°50\'N16°22\'E)中密封的骨沉积物的独特年代学。该沉积物的历史可追溯到从晚冰川末期[到现在(kacalB.P.)之前的约1.3万年校准]到全新世的最大热(〜5.6kacalB.P.)的气候变暖时期。古遗传分析使我们能够利用1000个形态学上无法识别的骨骼碎片,从而产生具有40个不同分类单元的高分辨率序列,包括以前在这里没有发现的物种。我们的记录显示,在过去的变暖时期,北极圈上方的海洋和陆地环境中都是一种自然反复出现的现象,提供对当今正在进行的整个生态系统响应的基本见解。
    Paleo-archives are essential for our understanding of species responses to climate warming, yet such archives are extremely rare in the Arctic. Here, we combine morphological analyses and bulk-bone metabarcoding to investigate a unique chronology of bone deposits sealed in the high-latitude Storsteinhola cave system (68°50\' N 16°22\' E) in Norway. This deposit dates to a period of climate warming from the end of the Late Glacial [~13 thousand calibrated years before the present (ka cal B.P.)] to the Holocene thermal maximum (~5.6 ka cal B.P.). Paleogenetic analyses allow us to exploit the 1000s of morphologically unidentifiable bone fragments resulting in a high-resolution sequence with 40 different taxa, including species not previously found here. Our record reveals borealization in both the marine and terrestrial environments above the Arctic Circle as a naturally recurring phenomenon in past periods of warming, providing fundamental insights into the ecosystem-wide responses that are ongoing today.
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  • 文章类型: Journal Article
    运输部门是欧洲国家温室气体排放增加的最大贡献者之一,私家车成为主要来源。尽管减少排放是一项艰巨的挑战,电池电动汽车(BEV)的出现为实现运输基础设施内的零温室气体提供了一条有前途且可持续的途径。自1990年代以来,挪威议会大力支持这一过渡,利用公众意识运动和一系列为全国用户提供的财政激励措施。BEV的广泛使用保证了巨大的健康益处,包括确保为所有公民提供更清洁的空气,无论其社会经济地位如何,并促进公共卫生结果的改善。这种转变可能会减少每年因气候变化造成的数十万人死亡,提高生活质量,提高平民生产力,促进经济和人口增长。采用BEV提供了无数的优势,包括降低健康风险和过早死亡,以及噪音污染减少的安静环境。尽管如此,BEV的集成需要强大的道路基础设施和可观的维护成本,以及用户驾驶范围的限制。与传统车辆相比,由于电池的重量增加,关于来自BEV轮胎磨损的潜在颗粒排放引起了关注。快速加速能力可能会加速轮胎退化,导致更高的颗粒物排放,其中只有10%到20%悬浮在空中,而大多数落在路面上,当被冲入水体和土壤时,对附近的水生生态系统构成威胁。虽然BEV持有有价值的好处的承诺,成功的政策制定和实施需要详细了解其局限性和挑战,以确保采取全面的方法来实现可持续的流动性和公共卫生改善。因此,对BEV局限性的更多研究可以帮助告知改进的策略,以最大限度地提高其利益,同时限制潜在的缺点。
    向电动汽车的迅速过渡是一种良好的公共卫生干预措施,有利于空气质量和气候系统。知道这项新技术不会解决交通系统引起的所有问题是有利的,因为新技术总是会像往常一样有一些不想要的和意想不到的副作用。我们建议对电动汽车的缺点进行更先进的研究,以便更好地理解和使用。
    The transportation sector is among the highest contributors to the increase in greenhouse gas emissions in European nations, with private cars emerging as the primary source. Although reducing emissions presents a formidable challenge, the emergence of battery electric vehicles (BEVs) offers a promising and sustainable avenue toward achieving zero greenhouse gases within the transportation infrastructure. Since the 1990s, the Norwegian parliament has fervently supported this transition, leveraging public awareness campaigns and a range of financial incentives for its users nationwide. The widespread utilization of BEVs promises substantial health benefits, including ensuring cleaner air for all citizens regardless of their socioeconomic status and fostering improvements in public health outcomes. This transition potentially curtails hundreds of thousands of annual deaths attributed to climate change, enhances the quality of life, bolsters civilian productivity, and fuels economic and population growth. The adoption of BEVs offers a myriad of advantages, including reduced health risks and premature mortality, as well as a quieter environment with diminished noise pollution. Nonetheless, the integration of BEVs necessitates robust road infrastructure with considerable maintenance costs, alongside limitations on driving range for users. Concerns arise regarding potential particle emissions from BEV tire wear due to the increased weight of batteries compared to conventional vehicles. Rapid acceleration capabilities may accelerate tire degradation, contributing to higher particle emissions, of which only 10% to 20% remain suspended in the air, whereas the majority settles on road surfaces, posing a threat to nearby aquatic ecosystems when washed into water bodies and soils. While BEVs hold promise for valuable benefits, successful policy creation and implementation require a detailed awareness of their limitations and challenges to ensure a comprehensive approach to sustainable mobility and public health improvement. Therefore, more research on the limitations of BEVs can help inform improved tactics for maximizing their benefits while limiting potential disadvantages.
    A swift transition to electric vehicles is a good public health intervention that benefits the quality of the air and climate systems. It is expedient to know that this new technology will not solve all problems caused by transportation systems, as there will always be some unwanted and unexpected side effects as usual with new technologies. We suggest more advanced research on EVs shortcomings for better understanding and usage.
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  • 文章类型: Journal Article
    气候变化和沿海生态系统已成为世界可持续发展的挑战性课题。人类,动物,和其他海洋栖息地主要受到气候有害变化的影响。沿海生态系统支持生物多样性和广泛的物种,这些物种是许多商业上重要的鱼类物种的栖息地,并增强了沿海地区的人类活动。通过参与沿海户外活动,个人可以体验到许多身心健康益处,培养环境意识。这项研究为沿海户外活动的重要性及其改善我们生活质量的潜力提供了宝贵的见解。这项研究进行了一个具有挑战性的主题,我们以图形和经济方式分析了沿海指标与其他气候相关因素之间的关系和联系。该研究包括世界上四个最大的海岸线国家之间的普通回归和比较分析。这项研究从加拿大抽取了一个样本,印度尼西亚,挪威,和俄罗斯联邦从1990年到2022年。在方便的基础上选择数据。结果表明,每个国家在减轻不利的气候变化和保持可持续的沿海生态系统方面都有其独特的挑战和机遇。这项研究令人惊讶地表明,气候变化对印度尼西亚和俄罗斯联邦的沿海生态系统影响不大,而对加拿大和挪威的沿海生态系统却产生了相反的影响。结果表明,加拿大和挪威的气候变化平均使沿海产量分别下降0.0041922和0.0261104。结果部分给出了详细的审查;然而,汇集分析证明,在总体水平上,气候变化增加1%导致四个最大海岸线国家的沿海生态系统减少0.02266吨。有必要制定政策,通过实施实际的海洋保护区来增加CAP活动。此外,科学研究和监测将有利于恢复沿海可持续性。
    Climate change and coastal ecosystems have become challenging subjects for world sustainability. Humans, animals, and other ocean habitats are primarily affected by the harmful changes in climate. Coastal ecosystems support biodiversity and a wide range of species that serve as habitats for many commercially important fish species and enhance human activities in coastal areas. By engaging in coastal outdoor activities, individuals can experience numerous physical and mental health benefits, foster environmental awareness. This study provided valuable insights into the importance of coastal outdoor activities and their potential to improve our quality of life. This study undertook a challenging subject where we graphically and econometrically analyze the relationship and linkages among coastal indicators with other climate-concerning factors. The study comprises the ordinary regression and comparative analysis among the four largest coastline countries in the world. The study took a sample from Canada, Indonesia, Norway, and the Russian Federation from 1990 to 2022. The data is selected on a convenient basis. Results declared that each country has its unique challenges and opportunities in mitigating adverse climate change and retaining a sustainable coastal ecosystem. The study surprisingly revealed that climate change insignificantly affects the coastal ecosystem in Indonesia and the Russian Federation while it inversely affects the coastal ecosystem in Canada and Norway, showed that climate change on average declines coastal production by 0.0041922 and 0.0261104 in Canada and Norway respectively. The detailed review is given in the results section; however, the pooling analysis proved that at the aggregate level, a one percent increase in climate change caused a 0.02266-tonne decline in coastal ecosystems in the four largest coastline nations. There is a need for policies tend to increase CAP activities by implementing practical marine protected areas. Furthermore, scientific research and monitoring will be beneficial in restoring coastal sustainability.
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  • 文章类型: Journal Article
    不健康的老龄化带来了全球性的挑战,具有深刻的医疗保健和社会经济影响。减缓老龄化进程提供了一种有希望的方法来减轻一些与年龄有关的疾病的负担,比如痴呆症,促进老年人口健康长寿。为了应对人口老龄化的挑战,并着眼于未来,挪威和英国正在促进合作,由两国之间的“货币遵循合作协议”支持。首届挪威-英国老龄化和痴呆症联席会议聚集了两国领先的老龄化和痴呆症专家,分享了他们在相关领域的最新发现。由于老龄化是一项国际挑战,并促进合作,我们还邀请了来自另外11个国家的著名学者参加这次活动。本报告提供了会议的摘要,强调分子老化机制的最新进展,遗传危险因素,DNA损伤和修复,线粒体自噬,自噬,以及一系列临床试验的进展(例如,使用NAD+前体)。会议促进了决策者之间的对话,行政领导,研究人员,和临床专家,旨在促进国际研究合作,并将研究结果转化为临床应用和干预措施,以促进健康老龄化。
    Unhealthy aging poses a global challenge with profound healthcare and socioeconomic implications. Slowing down the aging process offers a promising approach to reduce the burden of a number of age-related diseases, such as dementia, and promoting healthy longevity in the old population. In response to the challenge of the aging population and with a view to the future, Norway and the United Kingdom are fostering collaborations, supported by a \"Money Follows Cooperation agreement\" between the 2 nations. The inaugural Norway-UK joint meeting on aging and dementia gathered leading experts on aging and dementia from the 2 nations to share their latest discoveries in related fields. Since aging is an international challenge, and to foster collaborations, we also invited leading scholars from 11 additional countries to join this event. This report provides a summary of the conference, highlighting recent progress on molecular aging mechanisms, genetic risk factors, DNA damage and repair, mitophagy, autophagy, as well as progress on a series of clinical trials (eg, using NAD+ precursors). The meeting facilitated dialogue among policymakers, administrative leaders, researchers, and clinical experts, aiming to promote international research collaborations and to translate findings into clinical applications and interventions to advance healthy aging.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Journal Article
    尽管其在森林总生物量中所占份额很小,地面植被在生物地球化学循环中起着重要作用,能够改变碳(C)和养分通量。全球气候变暖可能会影响植物养分吸收和碳:氮:磷(C:N:P)化学计量,从土壤和土壤有机质中释放养分,以及显著影响林木养分供给。在这种情况下,挪威云杉(云杉(L.)H.喀斯特)地面植被对变暖的影响不确定。开放式室内土壤增温模拟,持续两个生长季节,是在云杉林里进行的.在两个生长季节的每一个结束时,在叶片衰老之前,从地块中收集了欧洲蓝莓(VaceminiummyrtillusL.)地上生物量(叶和茎)和矿物表土样品。C,N,P,微量营养素,和样品中的常量营养素浓度进行了估计。变暖导致C显着下降,N,和土壤中的P。变暖还降低了土壤中的C:P和N:P化学计量比,并增加了植物茎中的C:P比。在温暖的地块中观察到叶面C的显着增加和叶面P的减少。最明显的效果是减少土壤中的N和P,直接影响植物C:P和土壤N:P的化学计量。我们的结果表明,变暖导致蓝莓地上植物组织中某些营养素的含量显着下降。考虑到N是生态系统生产力的限制因素,由于变暖而导致的土壤减少可能对适当的养分吸收构成严重威胁,并导致生物地球化学循环中断。由于变暖而导致的地上组织中营养素含量的减少可导致生理过程的破坏。
    Despite its small share of total forest biomass, ground vegetation plays an important role in biogeochemical cycles, being able to modify carbon (C) and nutrients fluxes. Global climate warming may affect plant nutrient uptake and the carbon:nitrogen:phosphorus (C:N:P) stoichiometry, the release of nutrients from the soil and soil organic matter, as well as significantly influence the tree stand nutrient supply. In this context, the response of Norway spruce (Picea abies (L.) H.Karst) stands\' ground vegetation to warming is uncertain. An open-top chamber soil-warming simulation, lasting two growing seasons, was conducted in a spruce forest. At the end of each of the two growing seasons, before leaf senescence, European blueberry (Vaccinium myrtillus L.) aboveground biomass (leaves and stems) and mineral topsoil samples were collected from the plots. The C, N, P, micronutrient, and macronutrient concentrations were estimated in the samples. Warming caused significant decreases in C, N, and P in the soil. Warming also decreased the C:P and N:P stoichiometric ratios in the soil and increased the C:P ratio in plant stems. Significant increase in foliar C and decrease in foliar P in warmed plots were observed. The most evident effect was reduction of N and P in the soil, which directly affected the plant C:P and soil N:P stoichiometry. Our results show that warming has caused a significant decrease in the content of some nutrients in the aboveground plant tissues of blueberries. Given that N is a limiting factor of ecosystems productivity, its reduction in the soil caused by warming may be a serious threat to proper nutrient uptake and cause disruption of biogeochemical cycles. The decrease in nutrient content in aboveground tissues due to warming can result in disruptions to physiological processes.
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  • 文章类型: Journal Article
    结论:一个主要的抗黄锈性QTL,QYr。nmbu.6A,在整个欧洲的田间试验中贡献了一致的成年植物抗性,中国,肯尼亚和墨西哥。条锈病f.sp.Tritici,导致小麦黄锈(YR),是影响全球小麦产量的最具破坏性的生物营养病原体之一。由于PstS10竞赛小组最近在欧洲流行,自2014年以来,黄锈病已成为挪威的一种反复发生的疾病。由于所有阶段抗性(ASR)(或幼苗抗性)通常很容易通过病原体进化克服,耐久成虫植物抗性(APR)的部署对于黄锈病抗性育种至关重要。在这项研究中,在2015年至2021年的17项田间试验中,我们评估了北欧春小麦协会制图小组(n=301)的黄锈病抗性,其中包括四个不同大洲六个国家的9个地点。通过全基因组关联研究(GWAS)在各大洲鉴定了9个一致的QTL。6A染色体长臂上有一个稳健的QTL,QYr。nmbu.6A,在十七个试验中的九个中始终被检测到。QYr的单倍型分析。nmbu.6A证实了在所有测试环境中的显着QTL效应,并且还使用独立的挪威新育种系小组验证了该效应。与较老的品种和地方品种相比,在新品种和育种品系中发现了抗性单倍型的频率增加,这意味着由于欧洲黄锈病病原体种群的最新变化,可能已选择了抗性。
    CONCLUSIONS: A major yellow rust resistance QTL, QYr.nmbu.6A, contributed consistent adult plant resistance in field trials across Europe, China, Kenya and Mexico. Puccinia striiformis f. sp. tritici, causing wheat yellow rust (YR), is one of the most devastating biotrophic pathogens affecting global wheat yields. Owing to the recent epidemic of the PstS10 race group in Europe, yellow rust has become a reoccurring disease in Norway since 2014. As all stage resistances (ASR) (or seedling resistances) are usually easily overcome by pathogen evolution, deployment of durable adult plant resistance (APR) is crucial for yellow rust resistance breeding. In this study, we assessed a Nordic spring wheat association mapping panel (n = 301) for yellow rust field resistance in seventeen field trials from 2015 to 2021, including nine locations in six countries across four different continents. Nine consistent QTL were identified across continents by genome-wide association studies (GWAS). One robust QTL on the long arm of chromosome 6A, QYr.nmbu.6A, was consistently detected in nine out of the seventeen trials. Haplotype analysis of QYr.nmbu.6A confirmed significant QTL effects in all tested environments and the effect was also validated using an independent panel of new Norwegian breeding lines. Increased frequency of the resistant haplotype was found in new varieties and breeding lines in comparison to older varieties and landraces, implying that the resistance might have been selected for due to the recent changes in the yellow rust pathogen population in Europe.
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  • 文章类型: Case Reports
    大疱性类天疱疮(BP)伴sc疮是临床实践中很少遇到的疾病,当遇到它时,这通常是由于使用免疫抑制剂。本文是关于大疱性类天疱疮(BP)和c疮的患者的报告,服用地塞米松后出现结痂。应该注意大疱性类天疱疮抗体是必要的,这可以区分大疱性类天疱疮与sc疮和大疱性c疮,两种疾病的治疗方案不同。本文受版权保护。保留所有权利。
    Bullous pemphigoid (BP) with scabies is a condition rarely encountered in clinical practice, and when it is encountered, it is often due to the use of immunosuppressants. This paper is a report on a patient with BP and scabies, who developed scabs after taking dexamethasone. It should be noted that BP antibody is necessary, which can distinguish BP with scabies and bullous scabies, and the treatment options for the two diseases are different.
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  • 文章类型: Journal Article
    目的:调查估计的心肺适应性(eCRF)与总体发病率之间的关系。乳房,和前列腺癌在一项大型前瞻性队列研究中。
    方法:我们纳入了参加挪威Trøndelag健康研究第二次调查的46,968名无癌成年人。性别特异性非运动算法用于估计CRF。eCRF分为性别和年龄特异性三元,也就是说,低,中等和高水平。Cox比例风险模型用于计算风险比(HR)和95%置信区间(CI)。
    结果:平均随访22.1年,总共有7752个,858例乳腺癌和1376例前列腺癌。在所有参与者中,中等和高水平的eCRF以剂量-反应方式与总体癌症发病率降低相关(分别为HR0.96,95%CI0.90至1.01和HR0.85,95%CI0.79至0.91,和趋势<0.001的p值)。未观察到eCRF与女性乳腺癌发病率之间的关联。只有高水平的eCRF似乎与男性前列腺癌发病率降低相关(HR0.85,95%CI0.72至1.02)。
    结论:eCRF可能是研究CRF与癌症发病率之间关联的一种实用且具有成本效益的手段。
    To investigate the relationships between the estimated cardiorespiratory fitness (eCRF) and the incidence of overall, breast, and prostate cancer in a large prospective cohort study.
    We included 46,968 cancer-free adults who participated in the second survey of the Trøndelag Health Study in Norway. Sex-specific non-exercise algorithms were used to estimate CRF. eCRF was classified into sex and age-specific tertiles, that is, into low, medium and high levels. Cox proportional hazards models were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs).
    Over a median of 22.1 years\' follow-up, there were 7752 overall, 858 breast and 1376 prostate cancer cases. Medium and high levels of eCRF were associated with a reduced incidence of overall cancer in a dose-response manner in all participants (HR 0.96; 95% CI, 0.90-1.01 and HR 0.85; 95% CI, 0.79-0.91, respectively, and P-value for trend <.001). No association was observed between eCRF and breast cancer incidence in women. Only the high level of eCRF seemed to be associated with a reduced incidence of prostate cancer in men (HR 0.85; 95% CI, 0.72-1.02).
    eCRF may be a practical and cost-effective means of investigating the association between the CRF and cancer incidence.
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