Mucinous cystadenoma

黏液性囊腺瘤
  • 文章类型: Case Reports
    脐尿管残留是由于脐尿管闭合过程中的干扰而引起的疾病。一名55岁的男子被转诊到我们医院治疗胆结石。计算机断层扫描显示下腹部有一个与膀胱相连的囊性肿块。术前诊断为脐尿管囊肿。同期腹腔镜胆囊切除术,大量切除,并进行了尿道切除术。膀胱颅侧的肿块位于脐正中韧带。两者都被切除并移除,还有肚脐.术后病程顺利。组织病理学诊断为脐尿黏液性囊腺瘤。没有复发的迹象。完全切除而无损伤对于脐尿管残留的粘液性肿瘤尤其重要,因为对肿瘤的损伤可能导致腹膜假性粘液瘤的发展。英文文献中只报道了7例脐尿管残余粘液性囊腺瘤,其中只有一个接受了腹腔镜手术治疗。在我们的案例中,通过利用腹腔镜手术的放大效应,完全切除是可能的。此外,我们能够提供非常清晰的术中图像和标本照片,我们相信这将对读者有用。将来治疗类似病例时,腹腔镜手术将是有益的。然而,应该记住,安全的切除需要仔细和细致的技术。
    A urachal remnant is a disorder resulting from a disturbance in the closure process of the urachus. A 55-year-old man was referred to our hospital for treatment of gallstones. The computed tomography scan revealed a cystic mass in the lower abdomen connecting to the urinary bladder. The preoperative diagnosis was a urachal cyst. Simultaneous laparoscopic cholecystectomy, mass resection, and urachectomy were performed. The mass on the cranial side of the urinary bladder was located on the median umbilical ligament. Both were resected and removed, along with the umbilicus. The postoperative course was uneventful. The histopathological diagnosis was urachal mucinous cystadenoma. There is no sign of a recurrence. A complete resection without damage is especially important for mucinous tumors of the urachal remnant because the injury to the tumor may lead to the development of pseudomyxoma peritonei. Only seven cases of mucinous cystadenoma of the urachal remnant were reported in English literature, and only one of these was treated with laparoscopic surgery. In our case, complete resection was possible by taking advantage of the magnifying effect of laparoscopic surgery. Furthermore, we are able to provide very clear intraoperative images and specimen photographs, which we believe will be useful for readers. Laparoscopic surgery will be beneficial when treating similar cases in the future. However, it should be kept in mind that a safe resection requires careful and meticulous technique.
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  • 文章类型: Journal Article
    背景:唾液腺囊腺瘤(SGCA)是一种罕见的良性肿瘤,主要发生在腮腺。影响小唾液腺的SGCA并不常见,通常类似,临床和组织病理学,其他唾液腺病变。
    方法:本研究旨在描述一系列4例SGCA影响口内部位的病例,并对发表在英文文献中的SGCA进行文献综述。
    结果:本系列中包括的SGCA病例在颊粘膜中被诊断出,唇,19至78岁女性患者的硬腭。所有病例均接受切除活检,组织学特征为多囊性生长,包膜形成程度不同,并由几种类型的上皮衬里。包括SGCA中很少报告的一些细胞类型。在某些情况下,在囊性形成附近观察到少量淋巴细胞。所有SGCA都对高碘酸希夫呈阳性,免疫组织化学检测CK7和p63阳性。随访时间3~53个月,到目前为止,没有观察到复发。
    结论:文献综述显示,共有33项已发表的研究,占55例SGCA病例。
    BACKGROUND: Salivary gland cystadenoma (SGCA) is a rare benign tumor that predominantly occurs in the parotid gland. SGCAs affecting the minor salivary glands are uncommon and often resemble, clinically and histopathologically, other salivary gland lesions.
    METHODS: This study aimed to describe a series of four cases of SGCA affecting intraoral sites and performed a literature review of well-reported SGCA published in the English-language literature.
    RESULTS: SGCA cases included in this series were diagnosed in the buccal mucosa, lip, and hard palate of female patients aged between 19 and 78 years. All cases underwent excisional biopsy and were histologically characterized by a multicystic growth with variable degrees of capsule formation and were lined by several types of epithelium, including some cell types that are infrequently reported in SGCA. In some cases, a small collection of lymphocytes was observed adjacent to cystic formations. All SGCA were positive for periodic acid-Schiff, and immunohistochemical reactions were positive for CK7 and p63. The follow-up time ranged widely from 3 to 53 months, and to date, no recurrence has been observed.
    CONCLUSIONS: The literature review revealed a total of 33 published studies accounting for 55 SGCA cases.
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  • 文章类型: Journal Article
    背景:胰腺粘液性囊性肿瘤(MCN)表达雌激素和孕激素受体。一些病例报告描述了妊娠期间MCN的大小增加。这项研究的目的是评估妊娠是否是MCN恶性变性的危险因素。
    方法:纳入了2011年至2021年期间接受胰腺切除MCN的所有女性患者。在妊娠12个月内切除或诊断的MCN被定义为孕周。将具有高级别发育不良或侵入性成分的MCN分类为高级别(HG)组。主要结局定义为妊娠暴露和孕周MCN与HG-MCN发展之间的相关性。
    结果:该研究包括176名患者,25(14%)组成HG组,和151(86%)组成低等级(LG)组。LG和HG组的全身避孕药使用分布相似(26%vs.16%,p=0.262),和孕周MCN(7%对16%,p=0.108)。在单因素分析中,囊肿大小≥10cm(OR5.3,p<0.001)与HG变性有关。围妊娠MCN与囊肿大小呈正相关(R=0.18,p=0.020)。在14例孕周MCN患者的亚组中,29%的患者患有HG-MCN,71%的患者在妊娠期间出现囊肿生长,平均生长为55.1±18mm。
    结论:孕周MCN与囊肿直径增加有关,在妊娠期间受MCN影响的患者亚组中,观察到高增长率。有MCN和妊娠愿望的患者应接受多学科咨询。
    BACKGROUND: Mucinous cystic neoplasms (MCN) of the pancreas express estrogen and progesterone receptors. Several case reports describe MCN increasing in size during gestation. The aim of this study is to assess if pregnancy is a risk factor for malignant degeneration of MCN.
    METHODS: All female patients who underwent pancreatic resection of a MCN between 2011 and 2021 were included. MCN resected or diagnosed within 12 months of gestation were defined perigestational. MCN with high grade dysplasia or an invasive component were classified in the high grade (HG) group. The primary outcome was defined as the correlation between exposure to gestation and peri-gestational MCN to development of HG-MCN.
    RESULTS: The study includes 176 patients, 25 (14 %) forming the HG group, and 151 (86 %) forming the low grade (LG) group. LG and HG groups had a similar distribution of systemic contraceptives use (26 % vs. 16 %, p = 0.262), and perigestational MCN (7 % vs 16 %, p = 0.108). At univariate analysis cyst size ≥10 cm (OR 5.3, p < 0.001) was associated to HG degeneration. Peri gestational MCN positively correlated with cyst size (R = 0.18, p = 0.020). In the subgroup of 14 perigestational MCN patients 29 % had HG-MCN and 71 % experienced cyst growth during gestation with an average growth of 55.1 ± 18 mm.
    CONCLUSIONS: Perigestational MCN are associated to increased cyst diameter, and in the subset of patients affected by MCN during gestation a high rate of growth was observed. Patients with a MCN and pregnancy desire should undergo multidisciplinary counselling.
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  • 文章类型: Case Reports
    该病例报告显示卵巢粘液性囊腺瘤伴随黄色肉芽肿性卵巢炎的独特且前所未有的发生。一种罕见的炎症.据我们所知,这是医学文献中首例此类病例。病人,一个25岁的女人,出现腹痛,发烧,和不适,促使进一步的调查,导致意外发现这些共存的病理。
    This case report presents a unique and unprecedented occurrence of mucinous cystadenoma of the ovary accompanied by xanthogranulomatous oophoritis, a rare inflammatory condition. To the best of our knowledge, this is the first documented case of its kind in the medical literature. The patient, a 25-year-old woman, presented with abdominal pain, fever, and discomfort, prompting further investigation that led to the unexpected discovery of these coexisting pathologies.
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  • 文章类型: Case Reports
    背景:肠套叠在成人中是一种罕见的疾病,占肠套叠的5%,约占所有成人肠梗阻的1%。肿瘤起源是成人肠套叠最常见的病因,与小儿肠套叠不同,通常是特发性的。阑尾黏液囊肿引起的肠套叠异常,医学文献中只报道了少数病例。
    方法:我们报告一例25岁的非洲黑人男性患者,无病史。他因腹痛到急诊科就诊,恶心,和胆汁性呕吐。腹部检查显示典型的急性肠梗阻征象。增强腹肾盂CT显示最后一个回肠环内陷,盲肠,升结肠进入横结肠腔,圆形图像,低密度内容物和一些钙化与阑尾黏液囊肿相容。进行了紧急探查性腹腔镜检查,并确认了回盲肠肠套叠。行右半结肠切除术和回结肠吻合术。患者术后恢复顺利,4天后出院.手术标本的组织学检查证实了粘液性囊腺瘤的诊断。
    结论:以阑尾黏液囊肿为导点的成人肠套叠症状与其他肠套叠症状相似。通常通过注射腹部计算机断层扫描进行鉴别诊断。
    BACKGROUND: Intussusception is a rare condition in adults, accounting for 5% of intestinal intussusception and being responsible for approximately 1% of all adult bowel obstructions. Neoplastic origin is the most common etiology of intestinal intussusception in adults, unlike pediatric intussusception, which is usually idiopathic. Intussusception due to the appendiceal mucocele is exceptional, and only a few cases have been reported in the medical literature.
    METHODS: We report the case of a 25-year-old black African male patient with no medical history. He presented to the emergency department for abdominal pain, nausea, and bilious vomiting. The abdominal examination revealed typical signs of acute bowel obstruction. Enhanced abdominopelvic computed tomography showed an invagination of the last ileal loop, cecum, and ascending colon into the lumen of the transverse colon, with a rounded image with hypodense content and some calcifications compatible with an appendiceal mucocele. An emergency exploratory laparoscopy was performed and confirmed the ileocecocolic intussusception. Right hemicolectomy and ileocolic anastomosis were performed. The patient recovery postoperatively was uneventful, and he was discharged 4 days later. Histological examination of the surgical specimen confirmed the diagnosis of mucinous cystadenoma.
    CONCLUSIONS: The symptoms of bowel intussusception with the appendiceal mucocele as the lead point in adults are similar to any other bowel intussusception. Differential diagnosis is often carried out thanks to the injected abdominal computed tomography scan.
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  • 文章类型: Case Reports
    原发性睾丸交界性粘液性肿瘤极为罕见,属于卵巢上皮型。睾丸交界性粘液性肿瘤是良性粘液性囊腺瘤和粘液性癌之间的中间恶性肿瘤,其临床治疗以根治性睾丸切除术为主。报道的PBMTs病例预后良好,术后无复发或转移病例报道。然而,我们在此报告一名21岁男性,他可能是首例报告的睾丸PBMT术后肿瘤转移病例。
    Primary borderline mucinous tumor of the testis is extremely rare and belongs to the ovarian epithelial type. Testicular borderline mucinous tumor is intermediate in malignancy between benign mucinous cystadenoma and mucinous carcinoma, and their clinical treatment is mainly based on radical testicular resection. The reported cases with PBMTs have a good prognosis with no cases of recurrence or metastasis after surgery reported. However, we herein report a 21-year-old male who may be the first reported case of PBMT of the testis with postoperative tumor metastasis.
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  • 文章类型: Case Reports
    阑尾粘液囊肿是一种罕见的疾病,其特征是阑尾腔扩张并伴有粘液积聚。虽然这种疾病经常在阑尾切除术中偶然发现,术前区分急性阑尾炎和选择适当的手术治疗是至关重要的。我们介绍了一个31岁男性的病例,免费医疗,右侧腹痛伴有恶心和呕吐。他被诊断为阑尾黏液囊肿,并接受了腹腔镜阑尾切除术。缺乏独特的临床表现和生化参数,需要对阑尾粘液囊肿采取全面和协作的诊断方法。在手术前实现准确的诊断对于确保选择合适的手术技术至关重要。从而最大程度地减少了严重的术中和术后并发症的风险,例如腹膜假性黏液瘤。
    An appendiceal mucocele is a rare disease characterized by the dilation of the appendix lumen with mucus accumulation. Although this disease is often found incidentally during appendectomy, it is crucial to differentiate it from acute appendicitis preoperatively to select adequate surgical management. We present a case of a 31-year-old male, medically free, with right-sided abdominal pain associated with nausea and vomiting. He was diagnosed with appendiceal mucocele and underwent laparoscopic appendectomy. The absence of a distinct clinical presentation and biochemical parameters necessitates a comprehensive and collaborative diagnostic approach for mucocele of the appendix. Achieving an accurate diagnosis prior to surgery is imperative to ensure the appropriate surgical technique is chosen, thereby minimizing the risk of serious intraoperative and postoperative complications such as pseudomyxoma peritonei.
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  • 文章类型: Case Reports
    关于同卵双胞胎中发生卵巢肿瘤的报道有限。以前的大多数报告显示在两个双胞胎中都发现了卵巢畸胎瘤。在这里,我们首次报道了在双胞胎兄弟姐妹中发现的卵巢粘液性囊腺瘤伴对侧浆液性囊腺纤维瘤的病例。
    一名患者腹胀,随后的计算机断层扫描发现卵巢粘液性囊腺瘤。在腹腔镜检查期间,在对侧卵巢中发现了另一个卵巢肿块。组织病理学提示卵巢黏液性囊腺瘤伴对侧浆液性囊腺纤维瘤。双胞胎姐妹没有症状,但接受了妇科筛查。她也有类似的发现,粘液性囊腺瘤伴对侧卵巢浆液性囊腺纤维瘤。两名患者均接受腹腔镜双侧卵巢囊肿切除术。
    这是双胞胎同胞中关于左卵巢粘液性囊腺瘤伴右侧浆液性囊腺纤维瘤的首次临床报告。我们的病例支持双胞胎姐妹对卵巢肿瘤的认识。
    UNASSIGNED: There are limited reports on ovarian neoplasm occurring among identical twins. Most previous reports showed ovarian teratoma found in both twins. Herein, we report for the first time a case of ovarian mucinous cystadenoma with contralateral serous cystadenofibroma found in twin siblings.
    UNASSIGNED: One patient suffered from abdominal distension and the following computed tomography found ovarian mucinous cystadenoma. During the laparoscopy, another ovarian mass was found in the contralateral ovary. The histopathology revealed ovarian mucinous cystadenoma with contralateral serous cystadenofibroma. The twin sister had no symptoms but underwent gynecological screening. She also showed a similar finding, mucinous cystadenoma with serous cystadenofibroma on the contralateral ovary. Both patients underwent laparoscopic bilateral ovarian cystectomy.
    UNASSIGNED: This is the first clinical report on left ovarian mucinous cystadenoma with right serous cystadenofibroma in twin siblings. Our cases support awareness of ovarian tumors in twin sisters.
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  • 文章类型: Journal Article
    良性Brenner肿瘤和粘液性囊腺瘤的共存是罕见的,他们的关系和起源仍然是神秘和具有挑战性的。
    在这份手稿中,作者报告了一例62岁的未产叙利亚妇女,她出现严重的腹胀,随后进行剖腹手术并切除25×20cm囊肿;其病理检查证实了良性Brenner肿瘤和粘液性囊腺瘤。
    OvarianBrenner和黏液通常是良性的,很少会渐近地生长到非常大的尺寸。在这里,作者旨在强调通过病理检查排除恶性肿瘤的重要性.
    Walthard细胞巢经历化生,根据其遗传改变产生不同种类的Brenner和粘液性肿瘤形成。本文增加了现有文献,它仍然很穷,通过提供来自叙利亚的这种罕见组合的第一例的证据,并回顾了不同的起源和鉴别诊断理论。需要更多的研究来探索这种组合的遗传起源,以提高我们对卵巢肿瘤的总体认识。
    The coexistence of a benign Brenner tumour and a mucinous cystadenoma is rare, and their relationship and origin are still enigmatic and challenging.
    UNASSIGNED: In this manuscript, the authors report a case of a 62-year-old nulliparous Syrian woman who presented with severe abdominal distension, which was followed by laparotomy and the excision of a 25×20 cm-cyst; its pathological examination confirmed a benign Brenner\'s tumour and mucinous cystadenoma.
    UNASSIGNED: Ovarian Brenner and mucinous are usually benign and can rarely grow asymptomatically to very big sizes. Herein, the authors aim to emphasize the importance of excluding malignancy by pathology examination.
    UNASSIGNED: Walthard cell nests undergo metaplasia to give rise to different kinds of Brenner and mucinous neoplasm formations according to their genetic alterations. This paper adds to the available literature, which is still poor, by providing evidence of the first case of this rare combination from Syria with a review of different theories of origin and differential diagnoses. More studies directed towards exploring this combination\'s genetic origin are needed to boost our understanding of ovarian tumours in general.
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  • 文章类型: Case Reports
    Mucinous cystadenoma of the appendix is a rare condition characterized by abnormal mucus accumulation in the appendiceal. Laparoscopic appendectomy is a common approach worldwide and can be used in the management of mucinous cystadenoma with lower postoperative complication rates. A 30-year-old female had sharp pain localized to the right abdomen for 2 days. It was aggravated by movement and associated with nausea and vomiting. Laboratory findings were normal, but the abdominal computerized tomography scan demonstrated a cystic tumor in the right abdomen dorsal to the cecum and the ascending colon. Diagnostic laparoscopy showed a large cystic mass well-circumscribed encapsulated involving the appendix in the lower right abdomen. After demonstrating pathologic examination, the final diagnosis was mucinous cystadenoma of the appendix. Management of the appendicular mucinous cystadenoma can be successfully achieved through atraumatic laparoscopic excision of the tumor, it is safe, feasible and has a short postoperative recovery period.
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