Graft

移植物
  • 文章类型: Case Reports
    霉菌性颈动脉假性动脉瘤对外科医生来说是一个挑战。它们是罕见的并且与高死亡率和发病率相关。
    我们报告了一例61岁男性颈动脉分叉部的真菌性假性动脉瘤。这个案子是分阶段处理的,从使用支架移植物的初始血管内控制开始,然后使用大隐静脉移植进行开放动脉重建。
    患者出院,颈动脉通畅,无感染或出血迹象。在1个月时进行计算机断层扫描,6个月,1年后证实移植物通畅良好,无脑缺血成像。
    颅外颈动脉的真菌性假性动脉瘤很少见,应始终进行手术治疗。这种疾病,尽管它很罕见,需要早期发现和治疗,以避免致命的结果。提出了一种混合分阶段的方法,与一期手术相比,以避免破裂和改善临床结果。这种方法涉及使用支架移植物结合抗生素治疗作为桥接治疗,直到可以进行明确的手术,以便使用自体移植物进行动脉重建。
    UNASSIGNED: Mycotic carotid pseudoaneurysms represent a challenge for surgeons. They are rare and associated with high mortality and morbidity.
    UNASSIGNED: We reported a case of a 61-year-old man with a mycotic pseudoaneurysm of carotid bifurcation. The case was managed by a staged procedure, starting with initial endovascular control using a stent graft, followed by open arterial reconstruction using a saphenous vein graft.
    UNASSIGNED: The patient was discharged home with a patent carotid artery and no sign of infection or bleeding. A computed tomography scan performed at 1 month, 6 months, and 1 year later confirmed good patency of the graft without imaging of cerebral ischemia.
    UNASSIGNED: Mycotic pseudoaneurysms of the extracranial carotid artery are rare and should always be treated surgically. This disease, despite its rarity, requires early detection and treatment to avoid fatal outcomes. A hybrid staged approach is suggested, compared to one-staged surgery, to avoid rupture and improve clinical outcomes. This approach involves using a stent graft combined with antibiotic therapy as bridge treatment until definitive surgery can be performed to enable arterial reconstruction with an autologous graft.
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  • 文章类型: Case Reports
    BACKGROUND: Loxoscelism is a toxic clinical condition caused by the bite of spiders of the genus Loxosceles, with wide distribution throughout the world.1 Phospholipase D is responsible for dermonecrosis, inflammation, platelet aggregation, hemolysis, alteration of vascular permeability, cytotoxicity, nephrotoxicity, acute renal failure, among other symptoms involved with this protein.
    METHODS: 27-year-old male patient, who began with a sudden episode of intense pain in the right hand, in the metacarpus and metacarpophalangeal joints. On clinical examination, the upper extremity was noted to have increased volume, extensive edema, hyperemia, and increased local temperature; The lesion progressed to extensive necrosis. Fasciotomies were performed, from distal to proximal, and release of the second and third finger compartment through longitudinal radial and ulnar incisions. A skin autograft was placed, obtained from the anterior surface of the right thigh. Opioid analgesics, non-steroidal anti-inflammatory drugs, corticosteroids, and antibiotics were administered. The skin biopsy reported: inflammatory infiltrate with neutrophils, ulceration, and bacterial colonies. After 27 days he had a favorable evolution, so he was discharged to his home, with follow-up by staff from the Outpatient Service.
    CONCLUSIONS: Cutaneous loxoscelism, as a cause of acute compartment syndrome of the hand, is rare, but should be considered in an area endemic for Loxosceles spp. Surgical decompression of the affected compartments represents a decisive factor in the treatment of patients.
    BACKGROUND: El loxoscelismo es un cuadro clínico tóxico provocado por la mordedura de arañas del género Loxosceles, con amplia distribución en todo el mundo.1 La fosfolipasa D es la responsable de la dermonecrosis, inflamación, agregación plaquetaria, hemólisis, alteración de la permeabilidad vascular, citotoxicidad, nefrotoxicidad, insuficiencia renal aguda, entre otros síntomas implicados con esta proteína.
    UNASSIGNED: Paciente masculino de 27 años, que inició con un cuadro repentino de dolor intenso en la mano derecha, en el metacarpo y las articulaciones metacarpofalángicas. Al examen clínico, la extremidad superior se percibió con aumento de volumen, edema extenso, hiperemia y aumento de la temperatura local; la lesión progresó a necrosis extensa. Se realizaron fasciotomías, de distal a proximal, y liberación del compartimento del segundo y tercer dedo a través de incisiones longitudinales radiales y cubitales. Se colocó un autoinjerto de piel, obtenido de la superficie anterior del muslo derecho. Se administraron analgésicos opioides, antiinflamatorios no esteroides, corticosteroides y antibióticos. La biopsia de piel reporto: infiltrado inflamatorio con neutrófilos, ulceración y colonias bacterianas. Luego de 27 días tuvo evolución favorable, por lo que se dio alta a su domicilio, con seguimiento por personal del servicio de Consulta externa.
    UNASSIGNED: El loxoscelismo cutáneo, como causa de síndrome compartimental agudo de la mano, es poco común, pero debe considerarse en un área endémica para Loxosceles spp. La descompresión quirúrgica de los compartimentos afectados representa un factor decisivo en el tratamiento de los pacientes.
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  • 文章类型: Case Reports
    胆石症等胆结石相关疾病对全球发病率和死亡率有显著影响。腹腔镜胆囊切除术(LC)是胆囊切除术的金标准,但与罕见但严重的并发症有关。包括肝动脉假性动脉瘤(PAs)。一名72岁的女性在最近的LC后出现急性腹痛和上消化道出血。实验室研究证实了血红蛋白水平为10g/dL的贫血。肝功能测试混乱,在209U/L时显示丙氨酸转氨酶(ALT)升高,天门冬氨酸氨基转移酶(AST)为472U/L,总胆红素水平为3.29mg/dL,和直接胆红素水平为2.7mg/dL。对比增强的计算机断层扫描显示,右肝动脉附近有PA。鉴于强烈怀疑肝脏PA是她症状的根源,介入放射科医师放置了血管内支架.手术后,患者表现出良好的临床过程,症状消失,八天后出院。此病例强调了早期识别LC后肝动脉PAs的重要性,可能危及生命的并发症.这也表明血管内支架放置可以是传统的经动脉栓塞治疗这些PA的有效替代方法。需要更多的研究来评估这两种方法的长期有效性和安全性。
    Gallstone-related diseases like cholelithiasis contribute significantly to global morbidity and mortality. Laparoscopic cholecystectomy (LC) is the gold standard for gallbladder removal but is associated with rare but severe complications, including hepatic artery pseudoaneurysms (PAs). A 72-year-old female presented with acute abdominal pain and upper gastrointestinal bleeding following a recent LC. Laboratory studies confirmed anemia with a hemoglobin level of 10 g/dL. Liver function tests were deranged, showing elevated alanine aminotransferase (ALT) at 209 U/L, aspartate aminotransferase (AST) at 472 U/L, total bilirubin levels at 3.29 mg/dL, and direct bilirubin levels at 2.7 mg/dL. A contrast-enhanced computed tomography scan revealed a PA adjacent to the right hepatic artery. Given the strong suspicion of a hepatic PA as the source of her symptoms, an endovascular stent was placed by an interventional radiologist. Post-procedure, the patient showed a favorable clinical course with cessation of symptoms and was discharged after eight days. This case emphasizes the importance of early identification of hepatic artery PAs following LC, a potentially life-threatening complication. It also suggests that endovascular stent placement can be an effective alternative to traditional transarterial embolization for managing these PAs. Additional research is needed to evaluate the long-term effectiveness and safety of these two methods in comparison.
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  • 文章类型: Case Reports
    此病例报告旨在描述半髋关节置换术在重建延迟的近端指间(PIP)关节骨折脱位中的临床结果和技术考虑。它强调了该程序的可行性,可以作为复杂手指损伤延迟提示的重建选择。一名23岁的男性在受伤后六周出现左食指PIP关节骨折脱位。由于延迟提交和伤害的性质,传统的管理选择受到限制。使用自体骨软骨半乳腺癌移植物进行手术干预以重建关节表面。在这里,我们描述了详细的手术步骤,术后护理,和康复协议。经过五个月的随访,患者表现出显著的功能改善。PIP关节的运动范围大大增加,疼痛水平显着降低。射线照相评估显示成功的移植物结合和关节对齐。患者报告对美学和功能结果满意,强调术后生活质量的提高。对于延迟的PIP关节骨折脱位,半髋关节置换术是一种有利的手术选择。提供改善的关节一致性,接头稳定性,和功能结果。这种情况有助于越来越多的证据支持手术的有效性,并强调了在复杂的手损伤中考虑创新方法的重要性。
    This case report aims to delineate the clinical outcomes and technical considerations of hemi-hamate arthroplasty in the reconstruction of a delayed proximal interphalangeal (PIP) joint fracture-dislocation. It underscores the procedure\'s viability as a reconstructive option for complex finger injuries with delayed presentation. A 23-year-old male presented six weeks post-injury with a PIP joint fracture-dislocation of the left index finger. Traditional management options were limited due to the delayed presentation and the nature of the injury. A surgical intervention was performed using an autologous osteochondral hemi-hamate graft to reconstruct the articular surface. Herein, we describe the detailed surgical steps, postoperative care, and rehabilitation protocols. Over a five-month follow-up period, the patient demonstrated significant functional improvement. The range of motion in the PIP joint increased substantially, with a notable reduction in pain levels. Radiographic assessments showed successful graft incorporation and joint alignment. The patient reported satisfaction with the aesthetic and functional outcome, highlighting an enhanced quality of life post-surgery. Hemi-hamate arthroplasty emerges as a favorable surgical option for delayed PIP joint fracture-dislocations, offering improved articular congruity, joint stability, and functional outcomes. This case contributes to the growing body of evidence supporting the procedure\'s effectiveness and underscores the importance of considering innovative approaches in complex hand injuries.
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  • 文章类型: Case Reports
    背景:板层角膜移植术对治疗内皮功能障碍引起的角膜水肿有很大影响。微创移植技术,例如Descemet膜内皮角膜移植术(DMEK),有助于降低此类患者进行穿透性角膜移植术的发病率。即便如此,这些是复杂的技术,并非没有并发症,需要大量的外科学习和更苛刻的术后管理经验。
    方法:一名患有Fuchs内皮营养不良并接受白内障和DMEK联合手术的89岁女性在干预后24小时表现出主要为下层基质水肿和移植物部分脱离。在磋商中重新冒泡后,4天后,观察到移植物在前房滚动和游离。24小时后,她接受了重新DMEK,并保留了原始移植物,去上皮化以优化可视化。移植物用台盼蓝染色,后基质用空气保护。在眼内操作和气泡下重新植入移植物。手术后24小时,观察到粘附的移植物,间质水肿大大减少。一个月后,病人角膜透明,持续性完全移植物粘连,视力为0.9。
    结论:DMEK手术后前房自由滚动的发现构成了最复杂的移植物脱离形式。角膜水肿以及不同眼内结构的排列是这种并发症的手术解决所要考虑的条件。在许多情况下,手术重新定位移植物是可行的,这意味着节省成本,而无需使用新的供体角膜组织。
    BACKGROUND: Lamellar keratoplasties have had a great impact in the management of corneal edema due to endothelial dysfunction. Minimally invasive transplant techniques such as Descemet Membrane Endothelial Keratoplasty (DMEK) have helped to reduce the morbidity involved in performing penetrating keratoplasty in this type of patient. Even so, these are complex techniques that are not free of complications and require a long line of surgical learning and an even more demanding experience in postoperative management.
    METHODS: An 89-year-old woman suffering from Fuchs endothelial dystrophy and undergoing combined cataract and DMEK surgery presented stromal edema predominantly inferior and sectoral detachment of the graft 24 h after the intervention. After re-bubbling in consultations and 4 days later, the graft was observed rolled and free in the anterior chamber. She underwent re-DMEK with preservation of the original graft after 24 h, with de-epithelialization to optimize visualization. The graft was stained with trypan blue and the posterior stroma was protected with air. The graft was reimplanted under intraocular maneuvers and with an air bubble. 24 h after surgery, the adhered graft was observed, with a great decrease in stromal edema. One month later, the patient had a clear cornea, persistent complete graft adhesion, and visual acuity of 0.9.
    CONCLUSIONS: The discovery of free roll in the anterior chamber after DMEK surgery constitutes the most complex form of graft detachment. Corneal edema as well as the arrangement of the different intraocular structures are conditions to be considered for the surgical resolution of this complication. In many cases, surgical repositioning of the graft is feasible, which means saving costs without the need to use new donor corneal tissues.
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  • 文章类型: Journal Article
    探讨人工真皮联合自体厚皮移植治疗手部热压迫伤的临床效果。
    将2016年1月至2022年10月在我院接受热压缩伤口治疗的42例患者分为两组。自体皮移植后7天的成活率,操作的数量,总住院时间,住院总费用,并记录分泌物的细菌培养结果。视觉模拟量表用于评估伤口疼痛。记录皮肤移植物破裂的情况,并通过温哥华疤痕量表评估供体部位的疤痕状态。
    它显示了人造真皮的组合,厚薄皮肤自体移植,负压封闭引流技术通过提高植皮成活率(95.24%>66.67%),改善手部热压迫创面的治疗效果,减少操作次数(P<0.001),缓解伤口疼痛(P<0.001),有效控制伤口感染(4.76%<9.52%),术后植皮破裂率降低(4.8%<28.6%)。供者(P=0.003)和植皮区无明显瘢痕增生(P<0.001),手部功能恢复良好(P=0.037);这种治疗策略可延长住院时间(P=0.030),增加住院总费用(P=0.030).
    人工真皮和裂层皮肤的复合移植结合VSD显着改善了手部热压缩伤口患者的治疗和美学效果,值得在临床上推广应用。
    UNASSIGNED: To explore the clinical effect of artificial dermis combined with split-thickness skin autograft in treating hand thermal compression wounds.
    UNASSIGNED: Forty-two patients in our hospital from January 2016 to October 2022 with thermal compression wounds were divided into two groups. The survival rate of autologous skin grafts seven days after skin grafting, the number of operations, total hospital stay, total hospitalization cost, and bacterial culture results of secretions were recorded. The visual analog scale was used to evaluate the wound pain. The condition of skin graft rupture was recorded and the scar status of the donor site was evaluated by the Vancouver Scar Scale.
    UNASSIGNED: It showed combination of artificial dermis, split-thickness skin autograft, and vacuum sealing drainage improves the treatment of hand thermal compression wounds by enhancing the survival rate of skin grafting (95.24% > 66.67%), reducing the number of operations (P < 0.001), relieving wound pain (P < 0.001), effectively controlling wound infection (4.76% < 9.52%), and reducing the skin graft rupture rate after surgery (4.8% < 28.6%). There was no evident scar hyperplasia in the donor (P = 0.003) and skin graft areas (P < 0.001), which had a good recovery of hand function (P = 0.037); however, this treatment strategy may prolong the hospital stay (P = 0.030) and increase the total hospitalization cost (P = 0.030).
    UNASSIGNED: The composite transplantation of artificial dermis and split-thickness skin combined with the VSD significantly improves treatment and aesthetic outcomes in patients with thermal compression wounds to the hand, which is worth promoting and applying in clinical practice.
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  • 文章类型: Journal Article
    背景:DuraMatrix-Onlay®Plus是一种源自纯化的牛跟腱的硬脑膜胶原。所述基质提供用于胶原合成的支架,并且旨在用作高嵌体而不需要硬脑膜缝合线。该研究旨在描述我们对33例使用新型DuraMatrix-Onlay®Plus胶原硬脑膜进行硬脑膜成形术的连续患者的经验。
    方法:这是一个回顾性病例系列,包括33名在洛杉矶一家学术医院接受了硬脑膜成形术的患者,CA,2016年5月至2017年3月之间的美国。主要结果是脑脊液(CSF)漏的发生率。次要结果包括患者感染率,硬脑膜替代物并发症,和删除。
    结果:33例患者使用DuraMatrix-Onlay®Plus材料进行了硬脑膜成形术。患者的平均年龄为41.12±7.34岁(范围2-75岁)。女性18例(54.5%),男性15例(45.5%)。大多数手术是切除病变的选择性手术(n=19,58%),平均移植物大小为17.69±4.73cm²。平均随访3个月,术后无脑脊液漏.病人的感染率,硬脑膜替代物并发症,去除率为6%,6%,3%,分别。
    结论:DuraMatrix-Onlay®Plus与术后脑脊液漏发生率低和可接受的并发症有关。该结果支持在一般神经外科手术中使用胶原蛋白基质进行硬脑膜闭合。
    BACKGROUND: DuraMatrix-Onlay® Plus is a collagen dura membrane derived from purified bovine Achilles tendon. The matrix provides a scaffold for collagen synthesis and is intended to be used as an onlay without the need for dural sutures. The study aims to describe our experience with 33 consecutive patients who underwent a duraplasty procedure using the novel DuraMatrix-Onlay® Plus collagen dura membrane.
    METHODS: This is a retrospective case series of 33 patients who underwent a duraplasty procedure at a single academic hospital in Los Angeles, CA, USA between May 2016 and March 2017. The primary outcome was the incidence rate of cerebrospinal fluid (CSF) leak. Secondary outcomes included rates of patient infection, dural substitute complication, and removal.
    RESULTS: Thirty-three patients underwent a duraplasty procedure using the DuraMatrix-Onlay® Plus material. The average age of the patients was 41.12±7.34 years (range 2-75 years). There were 18 (54.5%) females and 15 (45.5%) males. The majority of procedures were elective operations for the resection of a lesion (n=19, 58%), and the average graft size was 17.69±4.73 cm². At an average follow-up of 3 months, there were no postoperative CSF leaks. The rates of patient infection, dural substitute complication, and removal were 6%, 6%, and 3%, respectively.
    CONCLUSIONS: DuraMatrix-Onlay® Plus is associated with a low rate of postoperative CSF leakage and an acceptable complication profile. This result supports the use of collagen matrices for dural closure in general neurosurgical procedures.
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  • 文章类型: Case Reports
    我们报告了一例75岁的糖尿病患者,该患者患有后颈坏死性筋膜炎并伴有蜂窝织炎。进行了重症监护和外科引流的医疗管理;顺序切除坏死组织会使颈区的物质大量损失,我们首先选择了定向愈合。讨论了局部旋转皮瓣或薄皮肤移植对这种物质损失的最终覆盖。然而,被病人拒绝了。
    We report the case of a 75-year-old diabetic patient who presented with posterior cervical necrotizing fasciitis complicating cellulitis. Medical management in intensive care and surgical drainage were undertaken; sequential excision of the necrotic tissue left a large loss of substance of the nuchal region for which we opted for directed healing in the first instance. The definitive coverage of this loss of substance by locoregional rotation flap or by thin skin grafting was discussed. However, it was refused by the patient.
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  • 文章类型: Case Reports
    我们介绍了一例47岁的女性,头皮肿胀,最初被认为是三囊囊肿。两年后,她回到她的全科医生那里,头皮质量更大。活检后,组织学分析显示隆突性皮肤纤维肉瘤(DFSP)。然后她完全切除了肿瘤,导致干净的利润。
    We present a case of a 47-year-old female with a swelling on her scalp that was at first thought to be trichilemmal cysts. After two years, she returned to her general practitioner with a larger scalp mass. Following a biopsy, histological analysis revealed dermatofibrosarcoma protuberans (DFSP). She then had the tumor completely removed, resulting in clean margins.
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  • 文章类型: Case Reports
    尽管Hill-Sachs病变经常与复发性前肱骨脱位相关,对生物力学的理解以及具有接合或非接合性病变的重要性最近才得到更深入的研究。现在广泛接受的是,由于如果不及时治疗,症状复发的风险很高,因此接合病变可从手术中受益。已经描述的技术包括囊移位过程,肱骨头旋转截骨术,甚至股骨或肱骨头同种异体移植物。作者描述了一种替代治疗方法,该方法涉及自体三皮质松质骨骨移植物,以治疗复发性肱骨前脱位和大,参与希尔-萨克斯病变。
    一名33岁男性,有两次左肩前下脱位的临床病史,表现为慢性不稳定和巨大的Hill-Sachs缺损(约占肱骨头的30%),前唇病变,但无关节盂骨病变。缺损用量身定制的自体三皮质松质髂骨移植物治疗,并用无头加压螺钉固定。患者在术后5个月恢复到每天的活动,并且具有完整的活动范围,未观察到并发症。
    这似乎是一种安全无痛的技术,具有出色的功能效果,那应该,然而,未来将通过前瞻性随机对照试验进行验证。
    UNASSIGNED: Although Hill-Sachs lesions are frequently associated with recurrent anterior glenohumeral dislocation, understanding of biomechanics and the importance of having an engaging or non-engaging lesion has only been recently studied at more depth. It is now widely accepted that engaging lesions benefit from surgery due to the high risk of symptom recurrence if left untreated. Techniques that have been described include capsular shift procedures, rotational osteotomies of the humeral head, or even femoral or humeral head allografts. The authors describe an alternative treatment which involves autogenous tricorticocancellous iliac crest graft to treat the bony defect in a patient with recurrent anterior glenohumeral dislocation and a large, engaging Hill-Sachs lesion.
    UNASSIGNED: A 33-year-old male with clinical history of two anterior-inferior dislocations of the left shoulder presented with chronic instability and a large Hill-Sachs defect (about 30% of the humeral head) with an anterior labrum lesion but no glenoid bony lesion. The defect was treated with a tailored autogenous tricorticocancellous iliac crest graft and fixed with headless compression screws. The patient returned to every-day activities at 5 months postoperatively and has a complete range of motion no complications were observed.
    UNASSIGNED: This appears to be a safe and painless technique with excellent functional results, that should, however, be validated in the future with prospective randomized controlled trials.
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