关键词: artificial dermis graft thermal compression wound vacuum sealing drainage technology wound repair

来  源:   DOI:10.3389/fsurg.2023.1304333   PDF(Pubmed)

Abstract:
UNASSIGNED: To explore the clinical effect of artificial dermis combined with split-thickness skin autograft in treating hand thermal compression wounds.
UNASSIGNED: Forty-two patients in our hospital from January 2016 to October 2022 with thermal compression wounds were divided into two groups. The survival rate of autologous skin grafts seven days after skin grafting, the number of operations, total hospital stay, total hospitalization cost, and bacterial culture results of secretions were recorded. The visual analog scale was used to evaluate the wound pain. The condition of skin graft rupture was recorded and the scar status of the donor site was evaluated by the Vancouver Scar Scale.
UNASSIGNED: It showed combination of artificial dermis, split-thickness skin autograft, and vacuum sealing drainage improves the treatment of hand thermal compression wounds by enhancing the survival rate of skin grafting (95.24% > 66.67%), reducing the number of operations (P < 0.001), relieving wound pain (P < 0.001), effectively controlling wound infection (4.76% < 9.52%), and reducing the skin graft rupture rate after surgery (4.8% < 28.6%). There was no evident scar hyperplasia in the donor (P = 0.003) and skin graft areas (P < 0.001), which had a good recovery of hand function (P = 0.037); however, this treatment strategy may prolong the hospital stay (P = 0.030) and increase the total hospitalization cost (P = 0.030).
UNASSIGNED: The composite transplantation of artificial dermis and split-thickness skin combined with the VSD significantly improves treatment and aesthetic outcomes in patients with thermal compression wounds to the hand, which is worth promoting and applying in clinical practice.
摘要:
探讨人工真皮联合自体厚皮移植治疗手部热压迫伤的临床效果。
将2016年1月至2022年10月在我院接受热压缩伤口治疗的42例患者分为两组。自体皮移植后7天的成活率,操作的数量,总住院时间,住院总费用,并记录分泌物的细菌培养结果。视觉模拟量表用于评估伤口疼痛。记录皮肤移植物破裂的情况,并通过温哥华疤痕量表评估供体部位的疤痕状态。
它显示了人造真皮的组合,厚薄皮肤自体移植,负压封闭引流技术通过提高植皮成活率(95.24%>66.67%),改善手部热压迫创面的治疗效果,减少操作次数(P<0.001),缓解伤口疼痛(P<0.001),有效控制伤口感染(4.76%<9.52%),术后植皮破裂率降低(4.8%<28.6%)。供者(P=0.003)和植皮区无明显瘢痕增生(P<0.001),手部功能恢复良好(P=0.037);这种治疗策略可延长住院时间(P=0.030),增加住院总费用(P=0.030).
人工真皮和裂层皮肤的复合移植结合VSD显着改善了手部热压缩伤口患者的治疗和美学效果,值得在临床上推广应用。
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