Graft

移植物
  • 文章类型: Case Reports
    霉菌性颈动脉假性动脉瘤对外科医生来说是一个挑战。它们是罕见的并且与高死亡率和发病率相关。
    我们报告了一例61岁男性颈动脉分叉部的真菌性假性动脉瘤。这个案子是分阶段处理的,从使用支架移植物的初始血管内控制开始,然后使用大隐静脉移植进行开放动脉重建。
    患者出院,颈动脉通畅,无感染或出血迹象。在1个月时进行计算机断层扫描,6个月,1年后证实移植物通畅良好,无脑缺血成像。
    颅外颈动脉的真菌性假性动脉瘤很少见,应始终进行手术治疗。这种疾病,尽管它很罕见,需要早期发现和治疗,以避免致命的结果。提出了一种混合分阶段的方法,与一期手术相比,以避免破裂和改善临床结果。这种方法涉及使用支架移植物结合抗生素治疗作为桥接治疗,直到可以进行明确的手术,以便使用自体移植物进行动脉重建。
    UNASSIGNED: Mycotic carotid pseudoaneurysms represent a challenge for surgeons. They are rare and associated with high mortality and morbidity.
    UNASSIGNED: We reported a case of a 61-year-old man with a mycotic pseudoaneurysm of carotid bifurcation. The case was managed by a staged procedure, starting with initial endovascular control using a stent graft, followed by open arterial reconstruction using a saphenous vein graft.
    UNASSIGNED: The patient was discharged home with a patent carotid artery and no sign of infection or bleeding. A computed tomography scan performed at 1 month, 6 months, and 1 year later confirmed good patency of the graft without imaging of cerebral ischemia.
    UNASSIGNED: Mycotic pseudoaneurysms of the extracranial carotid artery are rare and should always be treated surgically. This disease, despite its rarity, requires early detection and treatment to avoid fatal outcomes. A hybrid staged approach is suggested, compared to one-staged surgery, to avoid rupture and improve clinical outcomes. This approach involves using a stent graft combined with antibiotic therapy as bridge treatment until definitive surgery can be performed to enable arterial reconstruction with an autologous graft.
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  • 文章类型: Journal Article
    目的:评估使用自体绳肌腱(HT)移植和使用股四头肌腱(QT)或骨-髌腱-骨(BPTB)自体移植或同种异体移植进行翻修前交叉韧带重建(r-ACLR)的患者的临床结果。
    方法:2023年8月8日检索了三个数据库。作者遵守了系统评价和荟萃分析的首选报告项目(PRISMA)和修订的多重系统评价评估(R-AMSTAR)指南以及Cochrane干预措施系统评价手册。人口统计数据,手术细节,患者报告结果测量(PROMs),不稳定率,提取失败和重返运动(RTS)。
    结果:本综述包括11项研究,包括859名患者。五项研究比较了HT和QT自体移植物。一项研究均报告了QT组的IKDC评分(p=0.04)和Tegner评分(p=0.04)。虽然一项研究均报告了较高的前平移(p=0.04),HT组的正枢轴移动率(p=0.03)和故障率(p=0.03)。六项研究比较了HT和BPTB自体移植物,其中一项研究均报告了BPTB组的Lysholm评分更高(p=0.02)和更少的左右前松弛(p<0.01)。两项研究比较了HT自体移植物和同种异体移植物,只有一项研究报告HT组比同种异体移植物组的RTS时间更快(p<0.001)。所有其他比较均不显著。
    结论:HT自体移植与QT或BPTB自体移植相比,r-ACLR的结果相似或较差。除r-ACLR的RTS时间更长外,同种异体移植物与HT自体移植物的结果相似。
    方法:三级。
    OBJECTIVE: To evaluate the clinical outcomes in patients undergoing revision anterior cruciate ligament reconstruction (r-ACLR) using hamstring tendon (HT) autografts with those using either quadriceps tendon (QT) or bone-patellar tendon-bone (BPTB) autografts or allografts.
    METHODS: Three databases were searched on 8 August 2023. The authors adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and Revised Assessment of Multiple Systematic Reviews (R-AMSTAR) guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. Data on demographics, surgical details, patient-reported outcome measures (PROMs), rates of instability, failure and return to sport (RTS) were extracted.
    RESULTS: Eleven studies comprising 859 patients were included in this review. Five studies compared HT and QT autografts. One study each reported greater IKDC scores (p = 0.04) and Tegner scores (p = 0.04) in the QT group, while one study each reported higher anterior translation (p = 0.04), rates of positive pivot shift (p = 0.03) and rates of failure (p = 0.03) in the HT group. Six studies compared HT and BPTB autografts with one study each reporting greater Lysholm scores (p = 0.02) and less side-to-side anterior laxity (p < 0.01) in the BPTB group. Two studies compared HT autografts with allografts with only one study reporting a faster time to RTS in the HT group than the allograft group (p < 0.001). All other comparisons were not significant.
    CONCLUSIONS: HT autografts result in either similar or inferior outcomes in r-ACLR when compared to QT or BPTB autograft options. Allografts resulted in similar outcomes to HT autografts apart from greater time to RTS for r-ACLR.
    METHODS: Level III.
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  • 文章类型: Journal Article
    目的:总结巩膜移植物在眼科中的使用历史和当前趋势。
    方法:我们通过MEDLINE和CochraneLibrary数据库对文献进行了综述。搜索词为“巩膜”,\"移植\",和“手术”。搜索产生了1596篇文章,其中192项评估为相关。相关文章按时间顺序排序,并根据使用巩膜移植物的方法,这使得一篇评论文章的发展成为可能。
    结果:自1950年代以来,巩膜已在许多不同的适应症中常规用于眼科。随着时间的推移,其中一些适应症实际上已经过时(例如,用于视网膜脱离的外科治疗),但是今天仍然有大量的应用(特别是在青光眼或眼部整形手术中使用,或作为巩膜或角膜缺陷的贴片)。
    结论:尽管与其他组织库产品相比,目前同种异体巩膜在眼科中的使用频率较低,并且其适应症的范围已部分缩小,由于其可用性和性质,它仍然是一种有用的材料。
    OBJECTIVE: To summarize the history and current trends in the use of scleral grafts in ophthalmology.
    METHODS: We conducted a review of the literature through the MEDLINE and Cochrane Library databases. The search terms were \"sclera\", \"graft\", and \"surgery\". The search resulted in 1596 articles, of which we evaluated 192 as relevant. The relevant articles were sorted chronologically and according to the method of using scleral grafts, which enabled the development of a review article.
    RESULTS: The sclera has been routinely used in ophthalmology since the 1950s in many different indications. Some of these indications have become practically obsolete over time (for example, use in the surgical management of retinal detachment), but a large number still find application today (especially use in glaucoma or oculoplastic surgery, or as a patch for a defect in the sclera or cornea).
    CONCLUSIONS: Even though allogeneic sclera is currently used less frequently in ophthalmology compared to other tissue banking products and the range of its indications has partially narrowed, it remains a useful material due to its availability and properties.
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  • 文章类型: Journal Article
    各种研究建议在拔牙后使用牙槽移植材料来保存牙槽。然而,没有单一的材料,已被接受为标准的保存插座。这项系统评价的目的是分析使用双相磷酸钙进行插座再生的证据。
    该团队根据在PROSPERO注册的协议进行了系统的文献检索。PubMed,OVID,和EMBASE数据库用于搜索。然后使用RAYYAN开源软件对文章进行筛选,以进行证据合成。
    在搜索中找到的240篇文章中,两项研究可纳入本综述.
    双相磷酸钙(60%羟基磷灰石,HA和40%β-磷酸三钙,β-TCP)在牙窝保存和骨再生质量方面具有显着的作用。
    UNASSIGNED: Various studies have suggested use of socket grafting materials after dental extraction for socket preservation. However, there is no single material that has been accepted as standard for preserving the socket. The purpose of this systematic review was to analyze the evidence for the use of biphasic calcium phosphate for socket regeneration.
    UNASSIGNED: The team conducted a systematic literature search in accordance with the protocol registered at PROSPERO. PubMed, OVID, and EMBASE databases were used in the search. The articles were then screened using RAYYAN open-source software for the synthesis of evidence.
    UNASSIGNED: Of the 240 articles found in the search, two studies could be included in the review.
    UNASSIGNED: Biphasic calcium phosphate (60% hydroxyapatite, HA and 40% beta-tricalcium phosphate, β-TCP) has a significant effect in the socket preservation and quality of bone regeneration.
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  • 文章类型: Case Reports
    切开复位内固定是治疗胫骨平台骨折的金标准。然而,尽管程序完善,但仍可观察到一些并发症.除了刚度,不愈合是胫骨平台骨折最常见的并发症。这些畸形畸形可以是关节内或关节外或组合。关节内或关节外截骨术是治疗年轻且活跃的患者不愈合而无明显关节损伤的良好选择。当畸形愈合与广泛的关节受累或最初的软骨损伤导致膝关节骨关节炎时,手术选择是用关节成形术完全置换膝关节。我们报告了一例胫骨平台骨折患者的病例,该患者最初是在传统的接骨术中进行治疗的,在治疗结束时并发膝关节持续疼痛和跛行。
    Open reduction with internal fixation is the gold standard treatment for tibial plateau fractures. However, some complications can be observed despite a well-established procedure. Apart from stiffness, malunion is the most frequent complication of tibial plateau fractures. These malunions may be intra-articular or extra-articular or combined. Intra-articular or extra-articular osteotomy is a good option to treat malunion in young and active patients without significant joint damage. When malunion is associated with extensive joint involvement or the initial cartilage damage has resulted in knee osteoarthritis, the surgical option is a total replacement of the knee joint with arthroplasty. We report the case of a patient with a tibial plateau fracture treated initially at a traditional bonesetter complicated at the end of the treatment with the persistent of the knee pain and limping.
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  • 文章类型: Journal Article
    与重返运动相比,前十字韧带(ACL)重建(ACLR)后重返工作(RTW)的时机是一个研究较少的里程碑。
    系统评价ACLR后RTW的发生率和术后时机。
    系统评价;证据水平,4.
    这项研究是根据2020PRISMA(系统审查和荟萃分析的首选报告项目)声明进行的。在PubMed中进行了文献检索,Embase,科克伦,以及用于报告ACLR后RTW的临床研究的Ovid数据库,2022年8月确定了806项研究。使用非随机研究方法学指数(MINORS)分级系统进行质量评估。从研究中提取以下数据:研究特征,队列人口统计,ACLR技术,伴随半月板和/或软骨手术,术前患者报告的结果,RTW的比率,以及ACLR后RTW所需的天数。
    共有13项研究符合纳入标准,总计1791名患者(86.4%为男性)。在评估研究的方法学质量中观察到广泛的差异(MINORS评分范围,8-17).76.8%的人使用了绳肌腱(HT)自体移植(n=1377;平均年龄,30.5岁),同种异体移植物占17.1%(n=308;平均年龄,33.1岁),韧带高级加固系统占2.5%(n=46;平均年龄,33.2岁),骨-髌腱-自体骨移植占2%(n=36;平均年龄,28.5岁),股四头肌腱自体移植占1.3%(n=24;平均年龄,24.1岁)。在纳入的患者中,99.1%(n=1781)报告术后RTW成功。RTW的平均时间为84.2天(范围,31.4-107.1天),适用于HT和69.5天(范围,49-56.6天)用于同种异体移植。
    虽然没有关于ACL损伤前后工作强度的数据,我们的研究结果表明,患者最常发生RTW在手术后90天内.同种异体移植物ACLR患者可能比接受HT自体移植物ACLR患者更早发生RTW。
    UNASSIGNED: The timing of return to work (RTW) after anterior cruciate ligament (ACL) reconstruction (ACLR) is a less studied milestone compared with return to sports.
    UNASSIGNED: To systematically review the rate and postoperative timing of RTW after ACLR.
    UNASSIGNED: Systematic review; Level of evidence, 4.
    UNASSIGNED: This study was conducted in accordance with the 2020 PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. A literature search was performed in PubMed, Embase, Cochrane, and Ovid databases for clinical studies reporting RTW after ACLR, and 806 studies were identified in August 2022. A quality assessment was performed using the Methodological Index of Nonrandomized Studies (MINORS) grading system. The following data were extracted from studies: study characteristics, cohort demographics, ACLR technique, concomitant meniscal and/or cartilage procedures, preoperative patient-reported outcomes, rates of RTW, and days required for RTW after ACLR.
    UNASSIGNED: A total of 13 studies met inclusion criteria, totaling 1791 patients (86.4% male). Wide variability was observed in the methodological quality of the assessed studies (MINORS score range, 8-17). Hamstring tendon (HT) autograft was used in 76.8% (n = 1377; mean age, 30.5 years old), allograft in 17.1% (n = 308; mean age, 33.1 years old), the ligament advanced reinforcement system in 2.5% (n = 46; mean age, 33.2 years old), bone-patellar tendon-bone autograft in 2% (n = 36; mean age, 28.5 years old), and quadriceps tendon autograft in 1.3% (n = 24; mean age, 24.1 years old). Among the included patients, 99.1% (n = 1781) reported successful RTW after surgery. The mean time to RTW was 84.2 days (range, 31.4-107.1 days) for HT and 69.5 days (range, 49-56.6 days) for allograft.
    UNASSIGNED: While data regarding work intensity before and after ACL injury were absent, our study results suggested that patients most often RTW within 90 days of surgery. Patients with allograft ACLR may RTW earlier than patients undergoing ACLR with HT autograft.
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  • 文章类型: Journal Article
    前交叉韧带(ACL)撕裂是最常见的运动相关损伤之一,在四年的运动参与窗口中,超过3%的运动员发生。非接触损伤是精英级别运动员ACL损伤最常见的机制,特别是在屈曲偏心加载时,膝关节外翻和外旋增加。由于这些伤病及其康复对运动员造成的巨大损失,一段时间以来,最佳治疗一直是人们非常感兴趣的主题。在过去的二十年中,许多ACL重建(ACLR)和修复技术已被实施和改进,导致这种类型的损伤有许多手术选择。特别是对高水平运动员的手术方法需要额外的关注,这在普通人群中可能是不必要的。优化高水平运动员ACL治疗的重要考虑因素包括选择修复与重建,外科技术,选择自体或同种异体移植,以及相关的伴随程序,包括其他伤害或加固技术以及对康复的关注。这里,我们讨论了从修复到重建的一系列手术技术,并比较和对比各种重建和加固技术以及相关的外科珍珠和陷阱。对于患有ACL损伤的运动员,通过包括本文讨论的原理的适当治疗可获得良好的结果。
    Anterior cruciate ligament (ACL) tears are one of the most common sport-related injuries and occur in greater than 3% of athletes in a four-year window of sports participation. Non-contact injuries are the most common mechanism for ACL injury in elite-level athletes, especially with increased valgus and external rotation of the knee when loading eccentrically in flexion. Because of the immense toll these injuries and their recovery take on athletes especially, optimal treatment has been a subject of great interest for some time. Many ACL reconstruction (ACLR) and repair techniques have been implemented and improved in the last two decades, leading to many surgical options for this type of injury. The surgical approach to high-level athletes in particular requires additional attention that may not be necessary in the general population. Important considerations for optimizing ACL treatment in high-level athletes include choosing repair vs. reconstruction, surgical techniques, choice of auto- or allograft, and associated concomitant procedures including other injuries or reinforcing techniques as well as attention to rehabilitation. Here, we discuss a range of surgical techniques from repair to reconstruction, and compare and contrast various reconstructive and reinforcing techniques as well as associated surgical pearls and pitfalls. Good outcomes for athletes suffering from ACL injury are attainable with proper treatment including the principles discussed herein.
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  • 文章类型: Journal Article
    本文介绍了神经营养性角膜病变(NK),由于各种原因导致的三叉神经功能障碍,导致角膜神经支配。角膜神经化(CN)的手术技术已经发展起来,旨在恢复角膜敏感性。最初于1972年提出,现代方法提供了较少侵入性的选择。CN可以通过直接方法(DCN)直接将敏感神经缝合到受影响的角膜或通过神经自动/同种异体移植间接(ICN)进行。手术的成功依赖于细致的供体神经选择和准备,通常涉及多学科团队。PubMed研究和相关文献的审查进行了关于手术入路,强调手术技术和供体神经的选择。后者考虑了诸如感觉完整性和与角膜的接近度等因素。最常用的是对侧或同侧滑车上(STN),眶上(SON)和耳大(GAN)神经。关于移植物的选择,文献中使用最多的是sural(SN),前臂外侧皮神经(LABCN),还有GAN的神经.另一个有希望的选择是同种异体移植物(来自尸体的无细胞化神经)。感觉恢复的意义及影响手术结局的因素,包括神经口径匹配和轴突再生,正在讨论。未来的方向强调侵入性较小的技术和无细胞神经同种异体移植物的潜力。总之,CN代表了治疗NK的有希望的途径,根据患者病史和外科专业知识提供量身定制的方法,新的新兴技术需要通过基础科学改进和临床试验进一步探索。
    The article introduces neurotrophic keratopathy (NK), a condition resulting from corneal denervation due to various causes of trigeminal nerve dysfunctions. Surgical techniques for corneal neurotization (CN) have evolved, aiming to restore corneal sensitivity. Initially proposed in 1972, modern approaches offer less invasive options. CN can be performed through a direct approach (DCN) directly suturing a sensitive nerve to the affected cornea or indirectly (ICN) through a nerve auto/allograft. Surgical success relies on meticulous donor nerve selection and preparation, often involving multidisciplinary teams. A PubMed research and review of the relevant literature was conducted regarding the surgical approach, emphasizing surgical techniques and the choice of the donor nerve. The latter considers factors like sensory integrity and proximity to the cornea. The most used are the contralateral or ipsilateral supratrochlear (STN), and the supraorbital (SON) and great auricular (GAN) nerves. Regarding the choice of grafts, the most used in the literature are the sural (SN), the lateral antebrachial cutaneous nerve (LABCN), and the GAN nerves. Another promising option is represented by allografts (acellularized nerves from cadavers). The significance of sensory recovery and factors influencing surgical outcomes, including nerve caliber matching and axonal regeneration, are discussed. Future directions emphasize less invasive techniques and the potential of acellular nerve allografts. In conclusion, CN represents a promising avenue in the treatment of NK, offering tailored approaches based on patient history and surgical expertise, with new emerging techniques warranting further exploration through basic science refinements and clinical trials.
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  • 文章类型: Journal Article
    目的:研究肠改道和重建手术在治疗Fournier坏疽(FG)中的作用,以促进泌尿科医师之间的多学科合作,结直肠和整形外科团队。
    方法:使用Medline数据库对文献进行了综述,Embase,2023年6月PubMed。该综述包括评估FG在重建手术或转移结肠造口术后的结果的研究。
    结果:现有证据表明肠改道和结肠造口术可以减少进一步清创的需要,缩短伤口愈合的时间,并促进FG患者的皮肤移植或皮瓣摄取。此外,造口的心理影响被证明不是患者的主要问题。然而,造口具有围手术期并发症的风险,因此可能延长住院时间。在审查FG重建的证据时,大的和深的缺陷似乎受益于皮肤移植或皮瓣。值得注意的是,由于担心睾丸的温度调节和对患者的心理影响,将睾丸埋在大腿袋中已不再受欢迎。
    结论:在FG管理中使用肠改道和重建手术是病例依赖性的。因此,在管理FG时,与结直肠和整形外科团队进行密切讨论是很重要的.
    OBJECTIVE: To examine the role of bowel diversion and reconstructive surgeries in managing Fournier\'s gangrene (FG) to facilitate multidisciplinary collaboration between urologists, colorectal and plastic surgery teams.
    METHODS: A review of the literature was conducted using the databases Medline, Embase, PubMed in June 2023. The review included studies that evaluated the outcomes of FG following reconstructive surgeries or diverting colostomies.
    RESULTS: The existing evidence suggests that bowel diversion and colostomy formation could reduce the need for further debridement, shorten the time to wound healing, and facilitate skin graft or flap uptake in patients with FG. Additionally, the psychological impact of a stoma was shown not to be a major concern for patients. However, stoma carries a risk of perioperative complications and therefore may prolong the length of hospital stay. In reviewing the evidence for reconstruction in FG, large and deep defects seem to benefit from skin grafts or flaps. Noticeably, burial of testicles in thigh pockets has grown out of favour due to concerns regarding the thermoregulation of the testicles and the psychological impact on patients.
    CONCLUSIONS: The use of bowel diversion and reconstructive surgeries in managing FG is case dependent. Therefore, it is important to have close discussions with colorectal and plastic surgery teams when managing FG.
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  • 文章类型: Review
    目的:总结巩膜移植物在眼科中的使用历史和当前趋势。
    方法:我们通过MEDLINE和CochraneLibrary数据库对文献进行了综述。搜索词为“巩膜”,\"移植\",和“手术”。搜索产生了1596篇文章,其中192项评估为相关。相关文章按时间顺序排序,并根据使用巩膜移植物的方法,这使得一篇评论文章的发展成为可能。
    结果:自1950年代以来,巩膜已在许多不同的适应症中常规用于眼科。随着时间的推移,其中一些适应症实际上已经过时(例如,用于视网膜脱离的外科治疗),但是今天仍然有大量的应用(特别是在青光眼或眼部整形手术中使用,或作为巩膜或角膜缺陷的贴片)。
    结论:尽管与其他组织库产品相比,目前同种异体巩膜在眼科中的使用频率较低,并且其适应症的范围已部分缩小,由于其可用性和性质,它仍然是一种有用的材料。
    To summarize the history and current trends in the use of scleral grafts in ophthalmology.
    We conducted a review of the literature through the MEDLINE and Cochrane Library databases. The search terms were \"sclera\", \"graft\", and \"surgery\". The search resulted in 1596 articles, of which we evaluated 192 as relevant. The relevant articles were sorted chronologically and according to the method of using scleral grafts, which enabled the development of a review article.
    The sclera has been routinely used in ophthalmology since the 1950s in many different indications. Some of these indications have become practically obsolete over time (for example, use in the surgical management of retinal detachment), but a large number still find application today (especially use in glaucoma or oculoplastic surgery, or as a patch for a defect in the sclera or cornea).
    Even though allogeneic sclera is currently used less frequently in ophthalmology compared to other tissue banking products and the range of its indications has partially narrowed, it remains a useful material due to its availability and properties.
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