在中国13个省市的23个中心进行了6236名受试者的不锈钢环VCu200和TCu200c的多中心比较临床研究。5年末随访率为96.0%。女性使用年数为6802.8的钢圈,VCu200为8373.3,TCU220c为8712.3。5年累计总延续率/100名妇女分别为55.8、68.6和72.4。VCu200和TCu220c的妊娠率显着降低(7.32%和7.24%,分别),而钢圈为20.21%。钢圈之间的5年驱逐率存在显着差异(19.0%),VCu200(9.7%),和TCU220c(5.6%)。在钢环组中,出血和/或疼痛的去除最低,其他2个模型之间没有显着差异。怀孕率,驱逐,农村地区因个人原因停业高于城市地区。TCu220c的排出风险仅受哺乳期插入的影响,而VCu220c排出的原因是年龄,gravida,和以前的宫内节育器使用。除了这三个因素,钢环的排出受子宫腔长度的影响。(作者修改)
A multicenter comparative clinical
study of the Stainless steel ring VCu 200 and TCu 200c in a cohort of 6236 subjects was conducted in 23 centers in 13 provinces and municipalities in China. The followup rate at the end of 5 years was 96.0%. Woman-years of use were 6802.8 for the steel ring, 8373.3 for VCu 200, and 8712.3 for TCu 220c. 5-year gross cumulative continuation rates/100 women were 55.8, 68.6, and 72.4 respectively. VCu 200 and TCu 220c had significantly lower pregnancy rates (7.32% and 7.24%, respectively) while that of the steel ring was 20.21%. There were significant differences in the 5-year expulsion rates among steel ring (19.0%), VCu 200 (9.7%), and TCu 220c (5.6%). The removal for bleeding and/or pain was the lowest in the steel ring group and there were no significant differences between the other 2 models. The rates of pregnancy, expulsion, and discontinuation due to personal reasons in the rural areas were higher than in urban areas. The expulsion risk of TCu 220c was only affected by insertion during lactation and the factors responsible for expulsion with the VCu 220c were age, gravida, and previous IUD use. In addition to these 3 factors, expulsion of the steel ring was influenced by the length of the uterine cavity. (author\'s modified)