Eyes

眼睛
  • 文章类型: Journal Article
    运动视觉是一个多学科的兴趣,旨在提高视觉系统的性能,以实现实践运动的好处,以及日常生活和预防保健。运动员练习的训练类型,他或她的身体状况,认知水平,和水平的疲劳状况影响的速度的反应时间和,因此,电机响应速度。特定的正交练习,使用技术设备,通过使用不稳定平台和双任务范式来恢复静态和动态姿势稳定性可以帮助达到预期的效果。这项对运动视觉的系统回顾的目的是评估现有的关于运动视觉的总体文献,特别注意视觉训练的效果及其在不同运动以及康复和预防环境中的应用。我们分析了1950年至2023年已发表的有关运动视觉在运动表现中的作用的英语语言研究。我们搜索了Medline数据库。PRISMA2020清单用于评估本次审查的透明度和可重复性。用Jadad量表对登记的论文进行了评估,Amstar2量表和纽卡斯尔-渥太华量表。25(16项研究,5评论,2评论,1社论,1份描述性论文)在476项研究中符合纳入标准。由于样本年龄的差异,不同的技术,研究参与者的治疗方法和不可评估文章的发现,未进行荟萃分析.本综述的局限性在于单一数据库研究,分析的研究包含无统计学代表性的样本量和缺乏对照组.没有标准化的测试来衡量性能。研究表明,视觉技能的发展可以使运动员预防损伤,可以改善任何年龄的运动表现和运动功能,即使视觉系统受损,也能获得自适应运动行为,由于任务重复和手势的熟悉。我们打算确定一种多学科方法和一种手动治疗方案,以优化运动视觉中涉及的电路,以增加所实现的结果,但为此还需要进一步的研究。
    Sport Vision is a speciality of multidisciplinary interest aimed at improving the performance of the visual system to achieve benefits in practiced sports, as well as in daily life and in preventive care. The type of training practiced by the athlete, his or her physical condition, cognitive level, and level of fatigue condition affects the speed of the reaction time and, consequently, the speed of motor response. Specific orthoptic exercises, the use of technological devices, the recovery of static and dynamic postural stability by using unstable platforms and the dual-task paradigm can help to achieve the expected results. The aim of this systematic review of Sport Vision was to assess the overall existing literature on Sport Vision, paying particular attention to the effects of visual training and its application in different sports and in rehabilitation and preventive settings. We analysed published English language studies about the role of sport vision in athletic performance from 1950 to 2023. We searched through the Medline database. The PRISMA 2020 checklist was used to assess the transparency and reproducibility of this review. The enrolled papers were evaluated with the Jadad Scale, Amstar 2 Scale and Newcastle-Ottawa Scale. 25 (16 studies, 5 reviews, 2 comments, 1 editorial, 1 descriptive paper) out of 476 studies met the inclusion criteria. Due to the variability in the age of the samples, the different techniques, the treatments among the participants in the studies and the finding of non-evaluable articles, a meta-analysis was not conducted. The limitations of this review are the single database research, the studies analyzed contain a non-statistically representative sample size and the lack of a control group. There is no standardized test to measure performance. It was shown that the development of visual skills can benefit athletes in injury prevention, and can lead to improved sports performance and motor function at any age, acquiring adaptive motor behaviour even when the visual system is impaired, due to task repetition and familiarity of the gesture. We intended to identify a multidisciplinary approach and a manual treatment scheme to optimize the circuitry involved in sport vision in order to increase the results that are achieved, but further studies will be needed to this end.
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  • 文章类型: Journal Article
    UNASSIGNED: To assess fetal and neonatal eyes abnormalities and their progression during the last ZIKV outbreak and summarize learned lessons.
    UNASSIGNED: A systematic review and meta-analysis was conducted by a team of obstetricians and ophthalmologists.
    UNASSIGNED: Studies reporting ocular abnormalities during the prenatal (n = 5) and postnatal (n = 24) periods were included in the analysis. In the prenatal period, the most common ocular findings were intraocular calcification cases (4/6, 66.6%) and microphthalmia (3/6, 50%). Postnatal ocular abnormalities of congenital ZIKV infection were described after birth in 479 cases. Among them microphthalmia was reported in 13 cases (13/479, 2.7%). Posterior segment (retina and optic nerve) was the most affected structure, consisting of pigmentary changes (229/479, 47.8%), macular chorioretinal atrophy (216/479, 45%), optic nerve atrophy (181/479, 37.8%), increased cup-to-disk ratio (190/479, 39.6.%), optic nerve hypoplasia (93/479,19.4%), vascular changes (26/479, 5.4%), and retinal coloboma (20/479, 4.1%). The anterior segment was involved in 4.6% (22/479) of cases, including cataract (9/479, 1.8%), lens subluxation (1/479, 0.2%), iris coloboma (5/479, 1%), and congenital glaucoma (7/479, 1.4%). These ocular anomalies were isolated in one case (1/479, 0.2%) and multiple anomalies were found in the other cases. Long-term visual disorders have been described, with no possible improvement and even a worsening of some of the ocular anomalies previously observed. No reactivation of ocular lesions was observed.
    UNASSIGNED: This review highlights the severe ocular abnormalities associated with congenital ZIKV infections. The importance of multidisciplinary communication between the obstetrician, the maternal-fetal medicine specialist, and the ophthalmologist is emphasized.
    UNASSIGNED: This systematic review was registered with the International Prospective Register of Systematic Reviews (PROSPERO), registration440 188.
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  • 文章类型: Review
    最近发生的两例视网膜中央动脉阻塞在原本不复杂的Tenon下阻塞导致白内障手术后视力明显丧失的病例,促使我们对此类病例进行文献综述。我们确定了在区域麻醉下进行眼科手术后的97例视网膜动脉阻塞患者,这些患者没有立即出现与阻塞相关的并发症。这些发生在各种眼内(87%)和眼外(13%)手术后,在广泛的年龄范围内(19-89岁)对有(59%)或没有(39%)已知危险因素的患者。麻醉技术包括40个球后块,36块,19次Tenon\'s块,一种局部麻醉剂和一种未指定的局部麻醉剂。利多卡因的不同强度,布比卡因,甲哌卡因和罗哌卡因,无论是单独还是各种组合,被使用。麻醉技术的细节通常在报告中不完整,这使得比较和分析变得困难。只有9例患者的病因(视神经鞘损伤)被确定,而其余患者的损伤机制尚不清楚。假定了各种机制;然而,由于患者的原因,原因可能是多方面的,手术和麻醉的危险因素,尤其是那些视网膜循环受损的患者。由于没有确定的风险因素,没有具体建议可以避免这一毁灭性的结果。我们提供了一些一般性考虑的理由,这可能会降低这种风险,并在需要时提出眼科手术的麻醉选择,基于我们的文献综述和个人经验。
    Two recent cases of central retinal artery occlusion under otherwise uncomplicated sub-Tenon\'s block that resulted in significant visual loss after cataract surgery prompted us to undertake a literature review of such cases. We identified 97 cases of retinal artery occlusion after ophthalmic surgery under regional anaesthesia that had no immediate signs of block-related complications. These occurred after various intraocular (87%) and extraocular (13%) operations, across a wide range of ages (19-89 years) on patients with (59%) or without (39%) known risk factors. The anaesthetic techniques included 40 retrobulbar blocks, 36 peribulbar blocks, 19 sub-Tenon\'s blocks, one topical anaesthetic and one unspecified local anaesthetic. Different strengths of lidocaine, bupivacaine, mepivacaine and ropivacaine, either alone or in various combinations, were used. The details of the anaesthetic techniques were often incomplete in the reports, which made comparison and analysis difficult. Only nine cases had their cause (optic nerve sheath injury) identified, while the mechanism of injury was unclear in the remaining patients. Various mechanisms were postulated; however, the cause was likely to be multifactorial due to patient, surgical and anaesthetic risk factors, especially in those with compromised retinal circulation. As there were no definite risk factors identified, no specific recommendations could be made to avoid this devastating outcome. We have provided rationales for some general considerations, which may reduce this risk, and propose anaesthetic options for ophthalmic surgery on the fellow eye if required, based both on our literature review and our personal experience.
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  • 文章类型: Systematic Review
    从1970年至2023年,系统概述了颗粒物对眼睛健康的各种后果,并根据急性,慢性,和遗传是用PubMed呈现的,研究门,谷歌学者,和科学直接数据库。关于医学方面的各种研究与眼睛和健康相关。然而,从应用的角度来看,关于眼表和空气污染的研究有限。这项研究的主要目的是揭示眼睛健康与空气污染之间的关系,特别是颗粒物,以及其他外部因素作为加重因素。这项工作的第二个目标是研究模仿人眼的现有模型。这项研究之后是在一个研讨会上进行问卷调查,其中基于暴露的调查是根据他们的活动标记的。本文建立了颗粒物及其对人体健康影响的关系,导致许多眼部疾病,如干眼症,结膜炎,近视,青光眼,还有沙眼.问卷调查结果显示,约有百分之六十八的在工场工作的人有流泪的症状,视力模糊,和情绪波动,而32%的人无症状。尽管有进行实验的方法,评估没有很好的定义;需要对眼睛上的颗粒沉积进行经验和数值求解。在眼部沉积建模领域存在很大差距。
    From the years 1970-2023, a systematic overview of the diverse consequences of particulate matter on eye health and a disease classification according to acute, chronic, and genetic are presented using the PubMed, Research Gate, Google Scholar, and Science Direct databases. Various studies on medical aspects correlate with the eye and health. However, from an application perspective, there is limited research on the ocular surface and air pollution. The main objective of the study is to uncover the relationship between eye health and air pollution, particularly particulate matter, along with other external factors acting as aggravators. The secondary goal of the work is to examine the existing models for mimicking human eyes. The study is followed by a questionnaire survey in a workshop, in which the exposure-based investigation was tagged based on their activity. This paper establishes a relationship between particulate matter and its influence on human health, leading to numerous eye diseases like dry eyes, conjunctivitis, myopia, glaucoma, and trachoma. The results of the questionnaire survey indicate that about 68% of the people working in the workshop are symptomatic with tears, blurred vision, and mood swings, while 32% of the people were asymptomatic. Although there are approaches for conducting experiments, the evaluation is not well defined; empirical and numerical solutions for particle deposition on the eye are needed. There prevails a broad gap in the arena of ocular deposition modeling.
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  • 文章类型: Journal Article
    UNASSIGNED:眼睑痉挛是肌张力障碍的一种类型,由于其各种临床表现未被很好地识别,因此通常会延迟诊断。这项研究的目的是提供其临床特征的全面图片,包括呈现特征,电机功能,和非运动的特点。
    UNASSIGNED:这是一个两部分的研究。第一部分涉及系统的文献综述,总结了从41例先前报告中获取的10,324例病例的临床特征。第二部分包括由张力障碍联盟研究人员收集的大型多中心队列中的884例患者的临床特征摘要。以及对导致肌张力障碍扩散到眼周区域以外的因素的分析。
    未经评估:对于文献和肌张力障碍联盟中的案例,眼睑痉挛出现在50年代,在女性中更为常见。许多人表现为非特异性运动症状,如眨眼增加(51.9%)或非运动感觉特征,如眼睛疼痛或疼痛(38.7%)。畏光(35.5%),或干眼症(10.7%)。非运动精神病特征也很常见,包括焦虑症(34-40%)和抑郁症(21-24%)。在肌张力障碍联盟队列中出现眼睑痉挛的病例中,61%的人经历了肌张力障碍向其他地区的传播,最常见的是口下颌区和颈部。与传播相关的特征包括眼睑痉挛的严重程度,肌张力障碍家族史,抑郁症,和焦虑。
    UNASSIGNED:这项研究提供了眼睑痉挛的运动和非运动特征的全面总结,以及对可能导致其诊断识别和自然史不佳的因素的新颖见解。
    UNASSIGNED: Blepharospasm is a type of dystonia where the diagnosis is often delayed because its varied clinical manifestations are not well recognized. The purpose of this study was to provide a comprehensive picture of its clinical features including presenting features, motor features, and non-motor features.
    UNASSIGNED: This was a two-part study. The first part involved a systematic literature review that summarized clinical features for 10,324 cases taken from 41 prior reports. The second part involved a summary of clinical features for 884 cases enrolled in a large multicenter cohort collected by the Dystonia Coalition investigators, along with an analysis of the factors that contribute to the spread of dystonia beyond the periocular region.
    UNASSIGNED: For cases in the literature and the Dystonia Coalition, blepharospasm emerged in the 50s and was more frequent in women. Many presented with non-specific motor symptoms such as increased blinking (51.9%) or non-motor sensory features such as eye soreness or pain (38.7%), photophobia (35.5%), or dry eyes (10.7%). Non-motor psychiatric features were also common including anxiety disorders (34-40%) and depression (21-24%). Among cases presenting with blepharospasm in the Dystonia Coalition cohort, 61% experienced spread of dystonia to other regions, most commonly the oromandibular region and neck. Features associated with spread included severity of blepharospasm, family history of dystonia, depression, and anxiety.
    UNASSIGNED: This study provides a comprehensive summary of motor and non-motor features of blepharospasm, along with novel insights into factors that may be responsible for its poor diagnostic recognition and natural history.
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  • 文章类型: Journal Article
    与研究较多的脊椎动物和昆虫相比,缺乏甲壳动物视觉知识。虽然甲壳动物的视觉系统通常在形态上是保守的,分子组分(即视蛋白)仍未得到充分研究。这篇综述旨在表征甲壳类动物谱系的视蛋白多样性,以综合观察视觉系统的进化。使用来自95个物种的公开数据,我们鉴定了视蛋白序列并按进化枝分类。我们的分析产生了485个推定的视觉视蛋白和141个非视觉视蛋白。视觉视蛋白分为六个分支:长波长敏感(LWS),中波长敏感(MWS)1和2,短波长或紫外线敏感(SWS/UVS)和一枝状的近生视蛋白,观察到多个LWS和MWS视蛋白拷贝。SWS/UVS视蛋白在大多数物种中相对保守。甲壳类动物头颅,与其他相比,Remipedia和Hexanauplia表现出减少的视觉视蛋白多样性,malacostracan十足动物具有最高的视蛋白多样性。从除头颅外的所有研究类别中鉴定出非视觉视蛋白。此外,一种新的非视觉甲壳类动物进化枝,发现了R型视蛋白(Rc)。这篇综述旨在为未来甲壳类动物视觉研究提供一个框架,强调在光谱表征和分子分析方面需要更多的工作。这篇文章是主题问题的一部分\'理解色彩视觉:分子,生理,节肢动物的神经元和行为研究。
    Knowledge of crustacean vision is lacking compared to the more well-studied vertebrates and insects. While crustacean visual systems are typically conserved morphologically, the molecular components (i.e. opsins) remain understudied. This review aims to characterize opsin diversity across crustacean lineages for an integrated view of visual system evolution. Using publicly available data from 95 species, we identified opsin sequences and classified them by clade. Our analysis produced 485 putative visual opsins and 141 non-visual opsins. The visual opsins were separated into six clades: long wavelength sensitive (LWS), middle wavelength sensitive (MWS) 1 and 2, short wavelength or ultraviolet sensitive (SWS/UVS) and a clade of thecostracan opsins, with multiple LWS and MWS opsin copies observed. The SWS/UVS opsins were relatively conserved in most species. The crustacean classes Cephalocarida, Remipedia and Hexanauplia exhibited reduced visual opsin diversity compared to others, with the malacostracan decapods having the highest opsin diversity. Non-visual opsins were identified from all investigated classes except Cephalocarida. Additionally, a novel clade of non-visual crustacean-specific, R-type opsins (Rc) was discovered. This review aims to provide a framework for future research on crustacean vision, with an emphasis on the need for more work in spectral characterization and molecular analysis. This article is part of the theme issue \'Understanding colour vision: molecular, physiological, neuronal and behavioural studies in arthropods\'.
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  • 文章类型: Journal Article
    由于人口老龄化和与我们的生活方式相关的外源因素导致的病例数量不断增加,目前眼病是主要的公共卫生问题。因此,包括手术药理学方法在内的许多治疗方法已经出现,特别注意预防,在那里饮食起着重要作用。最近,潜在的抗氧化剂,如白藜芦醇,作为对抗各种眼部疾病的潜在工具,受到了很多关注。在这次审查中,我们专注于白藜芦醇抗眼部疾病的机制,特别是年龄相关性黄斑变性,青光眼,白内障,糖尿病视网膜病变,和玻璃体视网膜病变.我们分析,关于每种疾病的不同步骤,在多个层面上的白藜芦醇特性,如细胞和分子信号以及生理效应。我们展示并讨论了与活性氧的关系,炎症过程的调节,以及白藜芦醇如何通过激活sirtuin-1的潜在表观遗传作用来预防眼部疾病。最后,各种新形式的白藜芦醇给药正在出现,同时一些临床试验对白藜芦醇作为预防或治疗眼部疾病的潜在工具的未来提出了更多的疑问。需要更多的临床前研究来进一步了解RSV的潜在佐剂活性。
    Eye diseases are currently a major public health concern due to the growing number of cases resulting from both an aging of populations and exogenous factors linked to our lifestyles. Thus, many treatments including surgical pharmacological approaches have emerged, and special attention has been paid to prevention, where diet plays a preponderant role. Recently, potential antioxidants such as resveratrol have received much attention as potential tools against various ocular diseases. In this review, we focus on the mechanisms of resveratrol against ocular diseases, in particular age-related macular degeneration, glaucoma, cataract, diabetic retinopathy, and vitreoretinopathy. We analyze, in relation to the different steps of each disease, the resveratrol properties at multiple levels, such as cellular and molecular signaling as well as physiological effects. We show and discuss the relationship to reactive oxygen species, the regulation of inflammatory process, and how resveratrol can prevent ocular diseases through a potential epigenetic action by the activation of sirtuin-1. Lastly, various new forms of resveratrol delivery are emerging at the same time as some clinical trials are raising more questions about the future of resveratrol as a potential tool for prevention or in therapeutic strategies against ocular diseases. More preclinical studies are required to provide further insights into RSV\'s potential adjuvant activity.
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  • 文章类型: Journal Article
    Although visual avoidance of faces is a hallmark feature of social anxiety disorder (SAD) on clinical and theoretical grounds, empirical support is equivocal. This review aims to clarify under which conditions socially anxious individuals display visual avoidance of faces. Through a systematic search in Web of Science and PubMed up to March 2019 we identified 61 publications that met the inclusion criteria. We discuss the influence of three factors on the extent to which socially anxious individuals avoid looking at faces: (a) severity of social anxiety symptoms (diagnosed SAD versus High Social Anxiety levels in community samples [HSA] or related characteristics [Shyness, Fear of Negative Evaluation]), (b) three types of social situation (computer facial-viewing tasks, speaking tasks, social interactions), and (c) development (age-group). Adults with SAD exhibit visual avoidance across all three types of social situations, whereas adults with HSA exhibit visual avoidance in speaking and interaction tasks but not in facial-viewing tasks. The relatively few studies with children and adolescents suggest that visual avoidance emerges during adolescence. The findings are discussed in the context of cognitive-behavioral and skills-deficit models. Suggestions for future research include the need for developmental studies and more fine-grained analyses of specific areas of the face.
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  • 文章类型: Journal Article
    Gout is a clinical disorder that is characterized by the deposition of monosodium urate crystals (MSU) in joints and tendons, usually in the presence of prolonged hyperuricaemia. Following an asymptomatic phase of hyperuricaemia, gout usually presents as acute monoarthritis followed by periods of remission and exacerbation. Conjunctival hyperaemia and subconjunctival haemorrhage exacerbated by purine intake are two of the more common manifestations that may go unrecognized. Other ocular and adnexal structures can be affected by urate crystal deposition and associated inflammation, with potentially vision-threatening consequences; however, ocular manifestations of gout are rare and may have been over-reported in the older literature, but our understanding of the clinic-pathological features of ocular urate deposits remains limited.
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  • 文章类型: Journal Article
    Toxic effects on eyes result from exposure to pesticides via inhalation, ingestion, dermal contact and ocular exposure. Exposure of unprotected eyes to pesticides results in the absorption in ocular tissue and potential ocular toxicity. Recent literature on the risks of ocular toxicity from pesticide exposure is limited.Ocular toxicity from pesticide exposure, including the dose-response relationship, has been studied in different animal species. Cholinesterase enzymes have been detected in animal ocular tissue, with evidence of organophosphate-induced inhibition. Pathological effects of pesticides have been observed in conjunctiva, cornea, lens, retina and the optic nerve. Pesticide exposure has been associated with retinopathy in agricultural workers and wives of farmers who used pesticides. Saku disease, an optico-autonomic peripheral neuropathy, has been described in Japan in people living in an area where organophosphates were used. Pesticide exposure is also associated with abnormal ocular movements.Progressive toxic ocular effects leading to defective vision are a serious health concern. Agricultural workers are at high risk of exposure to pesticides and associated ocular toxicity. Primary prevention is the appropriate method of protecting eyes from pesticide-related damage. This includes improved eye safety and care in workplaces, and effective pesticide regulation for maintenance of public eye health.
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