研究报告了食用共轭亚油酸(CLA)和反刍动物反式脂肪酸(R-TFA)在减少代谢综合征(MetS)危险因素方面的潜在益处。此外,CLA和R-TFA的包封可以改善其口服递送并进一步降低MetS的危险因素。本综述的目的是(1)讨论封装的优势;(2)比较用于封装CLA和R-TFA的材料和技术;(3)审查封装的与未封装的CLA和R-TFA对MetS风险因素的影响。引用食品科学中使用的微米和纳米封装方法的论文检查,以及封装与非封装的CLA和R-TFA的影响,是使用PubMed数据库进行的。共审查了84篇论文;其中,选择了18项研究,其包含关于包封的CLA和R-TFA的作用的信息。描述CLA或R-TFA的包封的18项研究表明,微米或纳米包封过程稳定CLA并防止氧化。CLA主要使用碳水化合物或蛋白质包封。到目前为止,水包油乳化后喷雾干燥是CLA包封的常用技术。Further,4项研究调查了与未包封的CLA相比,包封的CLA对MetS风险因子的影响。有限数量的研究调查了R-TFA的封装。包封的CLA或R-TFA对MetS危险因素的影响仍未得到充分研究;因此,需要进行其他研究,比较封装和非封装的CLA或R-TFA的效果。
Studies have reported the potential benefits of consuming conjugated linoleic acid (CLA) and ruminant trans fatty acids (R-TFAs) in reducing the risk factors of metabolic syndrome (MetS). In addition,
encapsulation of CLA and R-TFAs may improve their oral delivery and further decrease the risk factors of MetS. The objectives of this review were (1) to discuss the advantages of
encapsulation; (2) to compare the materials and techniques used for encapsulating CLA and R-TFAs; and (3) to review the effects of encapsulated vs non-encapsulated CLA and R-TFAs on MetS risk factors. Examination of papers citing micro- and nano-
encapsulation methods used in food sciences, as well as the effects of encapsulated vs non-encapsulated CLA and R-TFAs, was conducted using the PubMed database. A total of 84 papers were examined; of these, 18 studies were selected that contained information on the effects of encapsulated CLA and R-TFAs. The 18 studies that described
encapsulation of CLA or R-TFAs indicated that micro- or nano-
encapsulation processes stabilized CLA and prevented oxidation. CLA was mainly encapsulated using carbohydrates or proteins. So far, oil-in-water emulsification followed by spray-drying were the frequently used techniques for encapsulation of CLA. Further, 4 studies investigated the effects of encapsulated CLA on MetS risk factors compared with non-encapsulated CLA. A limited number of studies investigated the
encapsulation of R-TFAs. The effects of encapsulated CLA or R-TFAs on the risk factors for MetS remain understudied; thus, additional studies comparing the effects of encapsulated and non-encapsulated CLA or R-TFAs are needed.