背景技术这篇文章描述了一种通过在电极上使用氧化铁(Fe2O^)纳米颗粒来检测抗坏血酸(AA)的策略。FeO2O纳米颗粒在AA的氧化中表现出有效的电催化作用,导致峰值电流增加。传感器展示了一个宽的线性检测范围,低检测限,和对干扰物的高选择性,使其适用于食品分析和医疗诊断应用中的准确AA测量。这强调了基于Fe2RO纳米粒子的传感器用于精确AA检测的潜力。目的本研究的主要目的是开发一种用于鉴定抗坏血酸的电化学传感技术,使用Fe2O^纳米粒子作为传感基质。材料和方法合成过程涉及利用FeCl3·6H2O,氨溶液,乙醇,和双蒸馏水。将FeCl3·6H2O溶解在氨水中,产生棕色沉淀,用于合成Fe2O3纳米颗粒。随后,棕色沉淀物在180°C下进行水热处理,导致形成红色产品。离心后,washing,和干燥步骤,成功合成了Fe2MO纳米粒子。然后利用这些纳米颗粒来修饰玻碳电极(GCE)。在修改之前,GCE接受了抛光和清洁程序,之后,用含有5毫克Fe2O3纳米颗粒在10毫升乙醇中的悬浮液涂覆。将涂覆的电极干燥并认为准备用于电化学传感。结果本研究采用水热法合成了Fe2O3纳米颗粒,随后进行了一系列实验以评估其电化学传感能力。通过各种分析,确定所得到的FeO2O238纳米粒子具有高纯度和晶体结构,包括场发射扫描电子显微镜(FE-SEM),循环伏安测试,X射线衍射(XRD)能量色散X射线(EDX)光谱分析,差分脉冲伏安法(DPV),以及Fe2RO2修饰电极对抗坏血酸的电流响应。观察到Fe2O3纳米颗粒的形态是均匀的。通过对抗坏血酸表现出非常灵敏和选择性的敏感性,合成的颗粒成功地实现了研究的目标。结论我们的研究强调了利用基于Fe2O3纳米颗粒的电化学传感来检测抗坏血酸的潜力,抗坏血酸对Fe2O3纳米颗粒的高灵敏度证明了这一点。Fe2O纳米粒子的独特性质,其中包括它们的大表面积,高效的电子传输,和简单的制造过程,显着提高传感器的性能。进一步的研究对于探索传感器在食品安全等领域的广泛应用至关重要,环境监测,和生物诊断,并克服任何现有的限制。
Background The article delineates a strategy for detecting ascorbic acid (AA) through the use of iron oxide (Fe₂O₃) nanoparticles on an electrode. The Fe₂O₃ nanoparticles demonstrated effective electrocatalysis in the oxidation of AA, resulting in increased peak currents. The sensor showcased a wide linear detection range, a low detection limit, and high selectivity towards interferents, making it suitable for accurate AA measurement in food analysis and medical diagnostics applications. This emphasizes the potential of Fe₂O₃ nanoparticle-based sensors for precise AA detection. Aim The primary aim of this research is to develop an electrochemical sensing technique for the identification of ascorbic acid, with the use of Fe₂O₃ nanoparticles as the sensing matrix. Materials and methods The synthesis process involved the utilization of FeCl3.6H2O, ammonia solution, ethanol, and double-distilled water. FeCl3.6H2O was dissolved in ammonia water to produce a brown precipitate for the synthesis of Fe₂O₃ nanoparticles. Subsequently, the brown precipitate underwent hydrothermal treatment at 180 °C, resulting in the formation of a red product. Following centrifugation, washing, and drying steps, Fe₂O₃ nanoparticles were successfully synthesized. These nanoparticles were then utilized to modify the glassy carbon electrode (GCE). Prior to the modification, the GCE underwent polishing and cleaning procedures, after which it was coated with a suspension containing 5 mg of Fe₂O₃ nanoparticles in 10 mL of ethanol. The coated electrode was dried and deemed ready for application in electrochemical sensing. Results The hydrothermal method was employed in this research to synthesize Fe₂O₃ nanoparticles, which were subsequently subjected to a series of experiments to evaluate their electrochemical sensing capabilities. The resulting Fe₂O₃ nanoparticles were determined to possess a high level of purity and a crystalline structure through various analyses, including field emission-scanning electron microscopy (FE-SEM), cyclic voltammetric testing, X-ray diffraction (XRD), energy-dispersive X-ray (EDX) spectroscopy analysis, differential pulse voltammetry (DPV), and the current response of the Fe₂O₃-modified electrode towards ascorbic acid. The morphology of the Fe₂O₃ nanoparticles was observed to be uniform. The synthesized particles successfully fulfilled the study\'s objective by exhibiting remarkably sensitive and selective sensitivity towards ascorbic acid. Conclusion Our study underscores the potential of utilizing Fe₂O₃ nanoparticle-based electrochemical sensing to detect ascorbic acid, as evidenced by the notably high sensitivity of ascorbic acid towards Fe₂O₃ nanoparticles. The distinctive properties of Fe₂O₃ nanoparticles, which include their large surface area, efficient electron transport, and straightforward manufacturing process, significantly enhance the sensor\'s performance. Further research is crucial to exploring the wide-ranging applications of the sensor in fields such as food safety, environmental monitoring, and biological diagnostics and to overcome any existing limitations.