Abstract：
Zeolitic Imidazolate (metal organic) Frameworks (ZIFs) and Prussian Blue Analogues (PBAs) are promising materials in electrochemical sensing due to their unique properties. In this study, a composite material comprising NiFe-PBA and ZIF-67 was synthesized and made to form a uniform layer onto a glassy carbon electrode (GCE) to enhance electrochemical performance for furazolidone (FZD) detection. The synthesized NiFe-PBA/ZIF-67 composite exhibited excellent sensitivity, selectivity, and stability towards FZD detection, with a low limit of detection (LOD). The electrochemical behaviour of FZD on the NiFe-PBA/ZIF-67/GCE electrode was investigated, revealing a diffusion-controlled process. Differential pulse voltammetry (DPV) analysis demonstrated the synergetic effect of the PBA/MOF core-shell structure in enhancing FZD electro-reduction. The sensor exhibited exceptional LOD of 0.007 μM. Selectivity studies confirmed the sensor\'s ability to distinguish FZD from potential interferents. Extensive evaluations demonstrated the sensor\'s reproducibility, repeatability, and long-term stability, affirming its practical utility. Real sample analysis further validated the sensor\'s excellent analytical capabilities in diverse matrices.
摘要：
沸石咪唑（金属有机）骨架（ZIF）和普鲁士蓝类似物（PBA）由于其独特的性能而在电化学传感中是有前途的材料。在这项研究中,合成包含NiFe-PBA和ZIF-67的复合材料并使其在玻碳电极(GCE)上形成均匀层,以增强用于呋喃唑酮(FZD)检测的电化学性能。合成的NiFe-PBA/ZIF-67复合材料具有优异的灵敏度,选择性,和FZD检测的稳定性，具有低检测限（LOD）。研究了FZD在NiFe-PBA/ZIF-67/GCE电极上的电化学行为,揭示了一个扩散控制的过程。差分脉冲伏安法（DPV）分析表明PBA/MOF核-壳结构在增强FZD电还原中的协同作用。该传感器表现出0.007μM的异常LOD。选择性研究证实了传感器区分FZD与潜在干扰物的能力。广泛的评估证明了传感器的再现性，重复性,和长期稳定，肯定其实用性。真实样本分析进一步验证了传感器在不同矩阵中的出色分析能力。
