背景:和目的:植物化学物质被证明可有效靶向癌症中的许多信号通路。利用基于植物的支持与目前批准的化疗策略相结合可能证明是改善癌症患者治疗结果的可行方法。本研究旨在评估姜黄补充剂对紫杉醇化疗乳腺癌患者生活质量(QoL)和血液学参数的影响。
方法:本研究是一个前瞻性的连续病例系列,有60名参与者。使用标准问卷评估QoL,并从患者的医院记录中记录血液学参数。
结果:补充姜黄21天,全球健康状况有临床相关性和统计学意义的改善。症状评分(疲劳,恶心,呕吐,疼痛,食欲减退,失眠),和血液学参数。
结论:研究结果表明,补充姜黄可改善QoL,乳腺癌患者的症状缓解和血液学参数增加。
BACKGROUND: and purpose: Phytochemicals are proven to be effective in targeting numerous signaling pathways in cancer. Utilizing plant-based support in combination with currently approved chemotherapeutic strategies might prove a feasible method to improve therapeutic outcomes in cancer patients. The present study aimed to estimate the effect of turmeric supplementation on quality of life (QoL) and hematological parameters in breast cancer patients on Paclitaxel chemotherapy.
METHODS: The present study is a prospective consecutive
case series with 60 participants. QoL was assessed using a standard questionnaire and hematological parameters were recorded from the patients\' hospital records.
RESULTS: Turmeric supplementation for 21 days resulted in clinically relevant and statistically significant improvement in global health status, symptom scores (fatigue, nausea, vomiting, pain, appetite loss, insomnia), and hematological parameters.
CONCLUSIONS: The study findings show that turmeric supplementation improved QoL, brought about symptom palliation and increased hematological parameters in breast cancer patients.