Cerebrovascular Disorders

脑血管疾病
  • 文章类型: English Abstract
    Vascular cognitive impairment (VCI) refers to cognitive impairment primarily mainly caused by cerebrovascular pathologies and their risk factors. It is the second leading cause of cognitive impairment in individuals aged 60 and above in China. Currently, there are no specific treatments for VCI, but early identification and prevention can help reduce the risk of onset and improve patients\' prognosis. To raise awareness and attention among clinicians towards VCI and provide guidance for its standardized management, the Chinese Stroke Association Vascular Cognitive Impairment Subcommittee updated and revised the clinical classification, diagnostic procedures, neuropsychological evaluation criteria and imaging evaluation criteria and etc.on the basis of the Guidelines for the Diagnosis and Treatment of Vascular Cognitive Impairment in China (2019). Through systematic literature reviews, including meta-analysis, systematic review, randomized controlled trials, retrospective studies, clinical case-control studies, etc, evidence and recommendation levels were formulated according to the evaluation and evaluation criteria of recommendation classification, and a total of 8 recommendations were formed on the etiology, clinical classification, clinical manifestations, diagnostic criteria, prevention and treatment of VCI. A standardized diagnostic process for VCI suitable for the clinical practice in China was proposed, aiming at providing guidance for the standardized diagnosis and accurate treatment of VCI.
    血管性认知障碍(VCI)是指主要由脑血管病及其危险因素导致的认知功能障碍,是我国60岁及以上人群认知障碍的第二大原因。目前VCI尚无特效的治疗手段,但早期识别和预防有助于降低发病风险,改善患者预后。为了提高临床医师对VCI的知晓率及重视度,并为其规范化管理提供指导,中国卒中学会血管性认知障碍分会在《2019年中国血管性认知障碍诊治指南》的基础上,在临床分型、诊断流程、神经心理学评估标准、影像学评估标准等方面都进行了更新和修订,通过系统文献检索,包括荟萃分析、系统评价、随机对照试验、回顾性系列研究、临床病例对照研究等,根据国际指南标准化评级系统制订的推荐等级和证据水平分类,在VCI的病因及临床分型、临床表现、诊断标准、预防及治疗等方面共形成8条推荐意见,并提出了适合我国临床实践的VCI标准化诊断流程,以期为VCI规范化诊断和精准治疗提供指导方案。.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Review
    背景:我们对脑成像中发现的白质高强度(WMH)的理解存在范式转变。它们曾经被认为是衰老的正常现象,因此,无需进一步调查。然而,现在的证据表明这些病变是大脑和心血管健康不良的标志,预示着中风的风险增加,认知能力下降,抑郁与死亡然而,没有针对全科医生和其他临床医生针对不同临床适应症进行脑部磁共振成像扫描的意外发现WMH的具体管理指南.根据中风神经科医生的文献综述和专家意见,医学和成像专家,和全科医生,我们提出了我们的共识声明,以指导成人中偶然发现的WMH的管理。
    结论:当在脑成像中发现偶然的WMH时:进行详细的病史和检查以筛查神经系统事件。调查潜在的未诊断或治疗不足的心血管危险因素,尤其是高血压和糖尿病。当发现危险因素时,开始强化和个性化的心血管风险管理。通过公认的指南治疗潜在的风险因素,但请注意,在没有替代适应症的情况下,不应将抗血小板和抗凝药物用于偶然的WMH。
    大脑健康的机会。我们认为在脑成像上偶然发现WMH代表了研究常见心血管危险因素和优化大脑健康的机会。这可以由全科医生或内科医生开始和监测,而不会延迟等待门诊神经病学检查。
    There is a paradigm shift in our understanding of white matter hyperintensities (WMH) found on brain imaging. They were once thought to be a normal phenomenon of ageing and, therefore, warranted no further investigation. However, evidence now suggests these lesions are markers of poor brain and cardiovascular health, portending an increased risk of stroke, cognitive decline, depression and death. Nevertheless, no specific guidelines exist for the management of incidentally found WMH for general medical practitioners and other clinicians ordering brain magnetic resonance imaging scans for diverse clinical indications. Informed by a literature review and expert opinion gleaned from stroke neurologists, medical and imaging specialists, and general practitioners, we present our consensus statement to guide the management of incidentally found WMH in adults.
    When incidental WMH are found on brain imaging: Perform a detailed history and examination to screen for neurological events. Investigate for potential undiagnosed or undertreated cardiovascular risk factors, especially hypertension and diabetes mellitus. Commence intensive and individualised cardiovascular risk management when risk factors are uncovered. Treat underlying risk factors via accepted guidelines but note that antiplatelet and anticoagulant medications should not be prescribed for incidental WMH in the absence of an alternative indication.
    A brain health opportunity. We consider the discovery of incidental WMH on brain imaging to represent an opportunity to investigate for common cardiovascular risk factors and to optimise brain health. This can be commenced and monitored by the general practitioner or physician without delay in waiting for an outpatient neurology review.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: English Abstract
    Ischemic stroke caused by acute large vessel occlusion is associated with high rates of disability and mortality. Endovascular interventional therapy is evidently an effective treatment for occlusion of large cerebral vessels within the relevant time window, but there is no established methodological standard for recanalization interventional therapy. The Professional Committee of Interventional Neurology in Chinese Research Hospital Association organized cerebrovascular disease experts in China and developed the expert consensus described herein, to provide a reference for clinicians to formulate technical strategies for recanalization of acute cerebral vascular occlusion.
    急性大动脉闭塞性卒中具有高病死率、高致残率的特点。血管内介入治疗已被证实是时间窗内脑部大动脉闭塞的有效治疗方案,但闭塞再通介入治疗的技术策略尚缺乏统一规范。为此,中国研究型医院学会介入神经病学专业委员会组织国内部分脑血管病专家就上述问题展开讨论,并达成共识,以期为临床医生在急性脑部大动脉闭塞再通介入治疗技术策略的制定中提供参考依据。.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Practice Guideline
    西班牙紧急放射学会(SERAU),西班牙神经放射学学会(SENR),西班牙神经病学会通过其脑血管疾病研究小组(GEECV-SEN)和西班牙医学放射学学会(SERAM)开会起草了这份共识文件,该文件将审查计算机断层扫描在中风患者中的使用。专注于其适应症,正确获取的技术和可能的解释错误。
    The Spanish Society of Emergency Radiology (SERAU), the Spanish Society of Neuroradiology (SENR), the Spanish Society of Neurology through its Cerebrovascular Diseases Study Group (GEECV-SEN) and the Spanish Society of Medical Radiology (SERAM) have met to draft this consensus document that will review the use of computed tomography in the stroke code patients, focusing on its indications, the technique for its correct acquisition and the possible interpretation mistakes.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Research Support, Non-U.S. Gov\'t
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • Intracranial aneurysm is a common disease in neurosurgery, and intraoperative vascular injury causes postoperative ischemic complications that seriously influence patient prognosis. Intraoperative neurophysiological monitoring (IONM) enables effective identification of early intraoperative ischemia and thus reduces related complications. The Clinical Neurophysiology Committee of the Chinese Research Hospital Association and the Neurosurgeons Branch of the Chinese Medical Doctor Association organized national experts in neurophysiology and cerebrovascular disease to develop this expert consensus based on a review of published guidelines, consensuses and clinical evidence both at home and abroad, and after Delphi expert consultation. A consensus was formed on four aspects, including commonly used IONM techniques and parameter settings, perioperative preparation and interpretation of results, the value of intraoperative electrophysiological monitoring of aneurysms at different sites, and electrophysiological monitoring in special cases. Moreover, according to level of evidence recommended by GRADE criteria, nine recommendations were put forward from the above four aspects to provide a reference for clinical intracranial aneurysm intraoperative neurophysiological monitoring practice.
    颅内动脉瘤是神经外科常见疾病,术中血管损伤引起术后缺血性并发症,严重影响患者预后。术中神经电生理监测(IONM)能有效识别早期术中缺血,减少相关并发症。中国研究型医院学会临床神经电生理专业委员会和中国医师协会神经外科医师分会神经电生理学组组织了全国神经电生理及脑血管病方面的专家,在回顾国内外已发布的指南共识和临床证据基础上,经过德尔菲专家咨询,制定了本专家共识。形成了常用的IONM技术及参数设置、围手术期准备与结果解读、不同部位动脉瘤术中电生理监测价值和特殊情况下电生理监测四个方面的共识。并根据GRADE证据等级标准,从上述四个方面给出了9条推荐意见,为临床颅内动脉瘤术中神经电生理监测实践提供参考。.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    银杏叶提取物(GBE50)分散片是一种新的标准化处方,被广泛应用于缺血性心脑血管疾病的治疗。然而,在临床应用中还存在很多问题。GBE50分散片的合理安全使用对患者的用药安全和临床预后至关重要。本共识由心脑血管疾病中西医临床专家共同制定,并遵循中国中药协会出版的《中成药临床专家共识手册》。本研究根据临床调查确定了临床问题,根据PICO临床问题搜索研究论文,进行证据评估,分类,并按等级制度推荐,并以名义分组技术达成专家共识。共识将证据与专家经验相结合。临床问题的充分证据符合"建议",而证据不足,无法提出建议。GBE50分散片的安全问题,如适应症,用法和剂量,和特殊人群的药物治疗,被定义为提高临床疗效,提倡合理用药,降低药物风险。这种共识需要根据未来实际应用中出现的临床问题和基于证据的更新进行修订。
    Ginkgo biloba Extract( GBE50) Dispersible Tablets is a new standardized prescription,which is widely used in the treatment of ischemic cardiovascular and cerebrovascular diseases. However,there are still many problems in its clinical application.Rational and safe use of GBE50 Dispersible Tablets is pivotal to the medication safety and clinical prognosis of patients. This consensus has been jointly formulated by clinical experts of traditional Chinese medicine and western medicine in cardiovascular and cerebrovascular diseases and followed the Manual for the Clinical Experts Consensus of Chinese Patent Medicine published by the China Association of Chinese Medicine. The present study identified clinical problems based on clinical investigation,searched the research papers according to PICO clinical problems,carried out evidence evaluation,classification,and recommendation by GRADE system,and reached the expert consensus with nominal group technique. The consensus combines evidence with expert experience. Sufficient evidence of clinical problems corresponds to " recommendations",while insufficient evidence to " suggestions". Safety issues of GBE50 Dispersible Tablets,such as indications,usage and dosage,and medication for special populations,are defined to improve clinical efficacy,promote rational medication,and reduce drug risks. This consensus needs to be revised based on emerging clinical issues and evidencebased updates in practical applications in the future.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    Venous sinus stenosis is a rare cerebrovascular disease. The management of venous sinus stenosis remains controversial. The evidence-based medical evidence was limited. There was not a specific consensus or guideline on the disease. This expert consensus provides an overview of cerebral venous sinus stenosis and comprehensive recommendations for the diagnosis, management, and interventional treatment by reviewing the relevant literature. The intended audience includes physicians and other healthcare providers who are responsible for patients with cerebral venous sinus stenosis. The present consensus aims to standardize and improve the clinical practice of venous sinus stenosis in China.
    脑静脉窦狭窄(venous sinus stenosis,VSS)是一种少见的脑血管疾病。目前针对静脉窦狭窄的诊断和治疗,临床上还存在分歧,相关循证医学证据资料相对有限。本共识通过回顾相关文献,概述了静脉窦狭窄的相关临床基础并为其诊断、管理和介入治疗提供建议。其目标读者为负责静脉窦狭窄诊断和介入治疗的医师以及其他相关接诊医师,旨在指导和规范该类疾病的临床实践。.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    接受康复的人经常会遇到营养问题,如营养不良,但是没有专门针对这些患者的康复和营养护理相结合的临床实践指南(CPG)。日本康复营养协会旨在开发用于康复营养的CPG,以支持日常实践中的临床决策。
    基于建议评估等级的CPG委员会和开发流程,开发和评估系统和《2014年临床实践指南开发思想手册》已建立。为接受脑血管疾病康复的患者定义了四个临床问题,髋部骨折,癌症,和急性疾病。使用MEDLINE搜索截至2020年4月的随机对照试验(RCT)文献,EMBASE,中部,和Ichushi-web数据库。筛选后,对全文论文进行了分析资格评估.随后,纳入系统评价的研究检查了它们的偏倚风险,并进行了荟萃分析。CPG发展委员会根据系统审查报告起草了指南。小组成员确定了最终建议。
    针对每种疾病/状况,基于4至9个RCTs提出了四项建议。证据的确定性从很低到很低。总的来说,加强营养护理对于脑血管病康复患者的建议较弱,髋部骨折,癌症,和急性疾病。
    本CPG为接受康复的个体提供了初步的营养护理建议。由于证据确定性低,纳入研究样本量小,需要更多高质量和更大的RCT来开发更实用的CPG。
    Individuals undergoing rehabilitation often experience nutritional problems such as malnutrition, but there are no clinical practice guidelines (CPGs) specifically tailored to the combination of rehabilitation and nutritional care for these patients. The Japanese Association for Rehabilitation Nutrition aimed to develop CPGs for rehabilitation nutrition to support clinical decision making in daily practice.
    A CPG committee and development process based on the Grading of Recommendations Assessment, Development and Evaluation system and the Minds Handbook for Clinical Practice Guideline Development 2014 was established. Four clinical questions were defined for patients undergoing rehabilitation for cerebrovascular disease, hip fracture, cancer, and acute illness. Literatures of randomised control trials (RCTs) up to April 2020 were searched for using the MEDLINE, EMBASE, CENTRAL, and Ichushi-web databases. After screening, full-text papers were assessed for eligibility for analysis. Subsequently, studies included in the systematic review were examined regarding their risk of bias, and underwent meta-analyses. A CPG development committee drafted the guidelines based on the systematic review report. Final recommendations were determined by the panel members.
    Four recommendations were made based on 4 to 9 RCTs for each disease/condition. The certainty of the evidence ranged from very low to low. Overall, the enhanced nutritional care was weakly recommended for rehabilitation patients with cerebrovascular disease, hip fracture, cancer, and acute illnesses.
    This CPG provides tentative recommendations for nutritional care of individuals undergoing rehabilitation. Due to low certainty of evidence and small sample sizes of the included studies, more high-quality and larger RCTs are needed to develop more practical CPGs.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

  • 文章类型: Journal Article
    Cerebrovascular disease is the leading cause of death and disability in China, causing a huge burden among patients and their families. Hence, stroke prevention is critical, especially in the high-risk population. Here, we present the evidence-based guideline suitable for the Chinese population.
    Literature search of PubMed and Cochrane library (from January 1964 to June 2019) was done. After thorough discussion among the writing group members, recommendations were listed and summarised. This guideline was reviewed and discussed by the fellow writing committees of the Chinese Stroke Association\'s Stroke.
    This evidence-based guideline was written in three parts: controlling the risk factors of stroke, utilisation of antiplatelet agents and assessing the risks of first-ever stroke. All recommendations were listed along with the recommending classes and levels of evidence.
    This guideline provides recommendations for primary prevention of cerebrovascular disease among high-risk population in China. Controlling related risk factors, appropriately using antiplatelet agents, assessing the risk of developing first-ever stroke should help reduce the rate of cerebrovascular disease in China.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

       PDF(Pubmed)

公众号