背景:中枢巨细胞肉芽肿(CGCG)是一种非肿瘤性良性病变。它主要在上颌骨和下颌骨中观察到,下颌骨是更多报道的病变部位。病变通常表现在下颌骨的前部区域,偶尔穿过中线。该病例报告了下颌骨后部的罕见表现,在无牙区域。
方法:一名33岁女性,6个月前有36和37牙拔牙史,主诉口腔肿块。口腔检查显示位于下颌骨左后部的牙槽脊上的扩张性多房性肿块(4×3cm),在33号牙齿周围延伸,有完整的咬肌。组织病理学发现与CGCG一致。因此,手术切除病灶,术后4个月随访期间未观察到临床或放射学复发.
结论:虽然在颌骨后部的CGCG以前的报告显示了引起下颌支破坏以及咬肌肿胀的破坏性病变,该病例报告无咬肌受累。此外,虽然一些研究将CGCG与牙齿支撑区域联系起来,我们的案例表明,即使在拔除后,也可能存在创伤性联系。
结论:该病例表现为后颌骨罕见的CGCG,特别是没有咬肌的参与。这也表明CGCG可以在缺牙区域出现。
BACKGROUND: Central Giant Cell Granuloma (CGCG) is a non-neoplastic benign lesion. It is primarily observed in the maxilla and mandible, with the mandible being the more reported site of the lesion. The lesion often manifests in the anterior regions of the mandible, extending occasionally across the midline. This
case reports a rare presentation in the posterior portion of the mandible, in an edentulous area.
METHODS: A 33-year-old female with a history of extraction of teeth 36 and 37 six months ago presented with a main complaint of a mass in the oral cavity. The oral examination revealed an expansive multilocular mass (4 × 3 cm) located on the alveolar ridge in the left posterior portion of the mandible, extending around tooth 33 with an intact masseter muscle. The histopathological findings were consistent with CGCG. Consequently, the lesion was surgically removed with no clinical or radiological recurrence observed during the 4-month post-operative follow-up.
CONCLUSIONS: While previous
reports of CGCG in the posterior portion of the jaw showed destructive lesions that caused mandibular ramus destruction along with swollen masseter muscle, this
case reports no involvement of the masseter muscle. Also, while some studies linked CGCG to tooth-bearing regions, our
case suggests a possible traumatic link even after extraction.
CONCLUSIONS: This
case presents a rare CGCG occurrence in the posterior jaw, notably without masseter muscle involvement. It also indicates that CGCG can manifest in edentulous regions.