Central giant cell granuloma

  • 文章类型: Journal Article
    回顾分析中心性巨细胞肉芽肿患者的临床和影像学特征,并复习相关文献,为中心性巨细胞肉芽肿的诊断和临床表现提供参考。
    回顾性选择7例中央性巨细胞肉芽肿患者作为研究对象,所有病例均经病理证实,并进行了相关影像学检查.所有七例病例都接受了CT扫描,3例接受了MRI扫描。将详细的临床特征与影像学发现进行比较,并根据其表现和影像学特征进行分析。
    临床特征,影像学特征因病变部位而异.CT特征包括不均匀致密的膨胀性肿块,导致骨破坏和皮质变薄。而MRI在T1和T2加权图像中具有低到等强度的特征。可能存在囊性变性,出血或含铁血黄素沉积或类骨质形成,这可能导致T1和T2信号变化。在对比研究中,病变不增强,但周围可能轻度增强。
    在T1加权和T2加权图像中,具有骨骼破坏和皮质变薄的不均匀致密的膨胀质量,并且在外周轻度增强,应考虑中枢巨细胞肉芽肿。
    UNASSIGNED: To review and analyze the clinical and imaging features of central giant cell granuloma patients and to review the relevant literatures for the diagnosis and clinical manifestation of central giant cell granuloma.
    UNASSIGNED: Seven cases of central giant cell granuloma were retrospectively selected for the study, all of which were confirmed by pathology and had relevant imaging investigations. All seven cases had undergone CT scan, three cases had undergone MRI scan. Detailed clinical features were compared along with the imaging findings and analysis was done on the basis of their presentation and imaging features.
    UNASSIGNED: The clinical features, radiologic features were varied according to the site of the lesion. CT features include unevenly dense expansile mass causing bone destruction and cortical thinning. While MRI features with low to iso-intensity in T1- and T2 weighted images. There may be presence of cystic degeneration, hemorrhage or hemosiderin deposits or osteoid formation, which can cause T1 and T2 signal changes. On contrast study, the lesion doesn\'t enhance but periphery may enhance mildly.
    UNASSIGNED: Unevenly dense expansile mass with bone destruction and cortical thinning with low to iso-intensity in T1 weighted and T2 weighted images and mildly enhance peripherally, Central giant cell granuloma should be considered.
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  • 文章类型: Case Reports
    BACKGROUND: Central giant cell granuloma (CGCG) is a rare, non-neoplastic, benign lesion that exhibits expansive and osteolytic biological behavior. CGCG treatment and management is challenging for clinicians.
    METHODS: This report presents the treatment and management of recurrent, aggressive CGCG after surgical resection. After informed consent was obtained, the patient underwent radiotherapy. The lesion size was reduced significantly, with no evidence of recurrence or malignant transformation.
    CONCLUSIONS: This treatment experience indicates that radiotherapy can be used as a rescue treatment for complicated CGCG involving vital neurovascular structures of the cranial base.
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