背景:虽然科学界广泛认识到身体活动(PA)在肿瘤学支持治疗中的益处,接受过化学或放射免疫疗法治疗的癌症幸存者很难满足PA的建议.这强调了确定影响积极生活方式采用和维持的因素并提出多层次模型(微观,中观-,和宏观层面),以更好地理解促进者和障碍。目前,没有社会生态模型可以解释乳房治疗后阶段的积极生活方式,结直肠,前列腺,和肺癌。
目的:目的是确定影响癌症患者积极生活方式的因素,并评估针对积极生活方式的个性化计划的可行性。目标将分三个阶段进行。第一阶段旨在阐明与癌症幸存者积极生活方式相关的因素。阶段2涉及根据先前确定的因素开发解释性模型,以创建针对肿瘤学治疗后的积极生活方式的量身定制的健康教育计划。第3阶段旨在评估该个性化健康教育计划在国家实施后的可行性和潜在效果。
方法:首先,对影响PA的因素的探索(第一阶段)将基于混合方法方法,使用解释性序列设计和多水平分析。定量阶段涉及从社会生态学的角度完成问卷。随后,一部分受访者将参与半结构化访谈,以帮助解释定量结果。此阶段旨在构建影响积极生活方式的因素模型,并根据我们的早期发现(阶段2)制定个性化的12周计划。在第三阶段,我们将实施我们的多中心,法国大都市150名身体不活动和久坐的癌症幸存者的多模式计划。将评估方案的可行性。通过连接设备和多维变量(如声明的PA和久坐行为)测量PA水平,PA准备就绪,动机,PA首选项,PA知识和技能,障碍和促进者将在计划之前和期间以及之后的52周进行评估。
结果:机构审查委员会于2020年4月批准了混合方法研究(第一阶段),干预措施(第三阶段)于2022年3月获得批准。招聘和数据收集于2022年4月开始,干预实施于2023年5月结束。数据收集和全面分析预计将于2024年7月完成。
结论:肿瘤治疗后身体活动的决定因素和因素(DEFACTO)研究旨在增进我们的理解,在我们的社会生态模型中,研究影响癌症幸存者积极生活方式的因素,并评估基于该模型的定制干预措施是否可以支持积极生活方式。
背景:ClinicalTrials.govNCT05354882;https://www.clinicaltrials.gov/研究/NCT05354882。
■DERR1-10.2196/52274。
While the scientific community widely recognizes the benefits of physical activity (PA) in oncology supportive care, cancer survivors who have undergone chemo- or radio-immunotherapy treatments struggle to meet PA recommendations. This underscores the importance of identifying factors influencing active lifestyle adoption and maintenance and proposing a multilevel model (micro-, meso-, and macrolevel) to better understand facilitators and barriers. Currently, no socioecological model explains an active lifestyle in the posttreatment phase of breast, colorectal, prostate, and lung cancers.
The objective is to identify factors influencing an active lifestyle in cancer survivorship and assess the feasibility of an individualized program targeting an active lifestyle. The objectives will be addressed in 3 stages. Stage 1 aims to elucidate factors associated with the active lifestyle of cancer survivors. Stage 2 involves developing an explanatory model based on previously identified factors to create a tailored health education program for an active lifestyle after oncology treatments. Stage 3 aims to evaluate the feasibility and potential effects of this personalized health education program after its national implementation.
First, the exploration of factors influencing PA (stage 1) will be based on a mixed methods approach, using an explanatory sequential design and multilevel analysis. The quantitative phase involves completing a questionnaire from a socioecological perspective. Subsequently, a subset of respondents will engage in semistructured interviews to aid in interpreting the quantitative results. This phase aims to construct a model of the factors influencing an active lifestyle and develop an individualized 12-week program based on our earlier findings (stage 2). In stage 3, we will implement our multicenter, multimodal program for 150 physically inactive and sedentary cancer survivors across metropolitan France. Program feasibility will be evaluated. Measured PA level by connected device and multidimensional variables such as declared PA and sedentary behaviors, PA readiness, motivation, PA preferences, PA knowledge and skills, and barriers and facilitators will be assessed before and during the program and 52 weeks afterward.
The institutional review board approved the mixed methods
study (phase 1) in April 2020, and the intervention (phase 3) was approved in March 2022. Recruitment and data collection commenced in April 2022, with intervention implementation concluded in May 2023. Data collection and full analysis are expected to be finalized by July 2024.
The Determinants and Factors of Physical Activity After Oncology Treatments (DEFACTO)
study seeks to enhance our understanding, within our socioecological model, of factors influencing an active lifestyle among cancer survivors and to assess whether a tailored intervention based on this model can support an active lifestyle.
ClinicalTrials.gov NCT05354882; https://www.clinicaltrials.gov/
study/NCT05354882.
DERR1-10.2196/52274.