%0 Journal Article
%T Barriers to participation in clinical trials of rural older adult cancer survivors: A qualitative study.
%A Arana-Chicas E
%A Prisco LMH
%A Sharma S
%A Stauffer F
%A Dauphin S
%A Ban-Hoefen M
%A Navarette J
%A Zittel J
%A Cupertino AP
%A Magnuson A
%A Mustian KM
%A Mohile SG
%J J Rural Health
%V 0
%N 0
%D 2024 Jun 7
%M 38847392
%F 5.667
%R 10.1111/jrh.12852
%X <B>BACKGROUND: </B>Currently, 64% of cancer survivors are aged 65+. Older cancer survivors have unique complications after chemotherapy and are often excluded from cancer clinical trials. Although there is research on barriers to clinical trial participation of older adult cancer survivors, to date no research has explored barriers to clinical trial participation unique to rural older adult cancer survivors.<BR><B>METHODS: </B>This study is a secondary qualitative analysis from a study exploring survivorship challenges of rural older adults. Eligible participants were rural residents over age 65 who have completed curative-intent chemotherapy in the past 12 months. Participants (n = 27) completed open-ended semi-structured interviews that included questions on barriers to clinical trial participation. Transcripts were coded independently by two coders using thematic analysis. We have adhered to the standards for reporting qualitative research.<BR><B>RESULTS: </B>Participants reported a variety of barriers that included limited knowledge and fear about clinical trials, transportation challenges, their physicians not informing them of clinical trials, and thinking they are too old to participate in clinical trials. However, participants also reported facilitators to participating in clinical trials, including acknowledging benefits to their own health and society, and understanding the importance of clinical trials.<BR><B>CONCLUSIONS: </B>Rural older cancer survivors face numerous interpersonal, intrapersonal, and organizational barriers to clinical trial participation. Aging- and location-sensitive interventions that focus on patients, their caregivers, and health care providers may lead to improved participation of rural older adult survivors into clinical trials.