Breast reconstruction

乳房重建
  • 文章类型: Case Reports
    叶状肿瘤是一种罕见的乳腺肿瘤,大小可变。巨型叶状是直径大于10厘米的叶状。临床上,巨大的叶状肿瘤呈现为可见的,迅速增长的肿块扭曲了乳房轮廓。此类肿瘤体积大,生长速度快,提示纤维腺瘤的叶状诊断。规划对这些肿瘤的标准治疗策略是相当具有挑战性的。虽然对于大多数巨大叶状病例,充分的手术切除无瘤切缘是治疗标准,交界性和恶性巨大叶状肿瘤可能需要更广泛的切除,因为它们的复发率很高。一些作者将全乳房切除术描述为巨大的边界线和恶性叶状的治疗选择,明确的利润。在2022年3月至2023年9月之间,我们的肿瘤外科部门介绍并手术了三例巨大的叶状。他们进行了保留乳头的乳房切除术,并使用胸前硅胶植入物进行了乳房重建。我们认为有了这样的程序,我们可以从广泛的,已被证明可以降低局部复发率的乳房切除术的安全边缘,同时考虑美学结果。
    Phyllodes tumor is an uncommon breast neoplasm that is present in variable sizes. Giant phyllodes are those larger than 10 cm in diameter. Clinically, giant phyllodes tumors present as a visible, rapidly growing mass distorting the breast contour. Such tumors with large size and rapid growth rate suggest a phyllode diagnosis of fibroadenoma. Planning a standard treatment strategy for these tumors is quite challenging. While adequate surgical excision with tumor-free resection margins is the standard of care for most giant phyllodes cases, borderline and malignant giant phyllodes tumors might require wider resections given their high recurrence rates. Some authors described total mastectomy as the treatment option for giant borderline and malignant phyllodes to obtain wide, clear margins. Between March 2022 and September 2023, our surgical oncology department presented and operated on three cases of giant phyllodes. They underwent a nipple-sparing mastectomy and immediate breast reconstruction using pre-pectoral silicone implants. We think that with such a procedure, we can benefit from the wide, safe margins of mastectomy that have been proven to decrease local recurrence rates while considering the aesthetic outcome.
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  • 文章类型: Case Reports
    乳房切除术后的乳房重建是乳腺癌治疗的关键组成部分,旨在改善患者的生活质量。然而,管理层充满了潜在的并发症,包括皮肤坏死和伤口裂开,这可以显着影响临床结果。
    我们报告了一个患者的独特病例,乳房切除术和放射治疗后的乳房重建5年,由于棕色隐居蜘蛛咬伤了重建的乳房,导致严重的皮肤坏死和伤口开裂。并发症需要皮肤清创,移除植入物,用背阔肌皮瓣进一步重建。
    该案例强调了乳房重建中蜘蛛咬伤引起的坏死的异常病因,并强调了处理此类并发症的挑战和战略考虑。在介绍时,患者受累的乳房区域表现出广泛坏死和伤口裂开的迹象,直接归因于棕色隐士蜘蛛毒液的细胞毒性作用。毒液的病理生理学涉及复杂的级联,导致局部和系统性影响。局部影响,以皮肤坏死为标志,在这种情况下,妥协的皮肤完整性。系统效应,在该患者中未观察到,但可能严重,可能包括溶血,凝血病,急性肾衰竭,突出棕色隐士蜘蛛叮咬的严重性。
    总而言之,这个案例说明了乳房再造的复杂性,乳房切除术后并发症,特别是那些由外界因素引起的,如棕色隐士蜘蛛叮咬。它强调了对不寻常的坏死和开裂病因的细致关注,证明了适应性手术策略的重要性以及对毒液病理生理学的透彻了解在确保患者成功结局方面的重要性。
    UNASSIGNED: Breast reconstruction following mastectomy is a critical component of breast cancer treatment, aimed at improving patient quality of life. However, the management is fraught with potential complications, including skin necrosis and wound dehiscence, which can significantly impact clinical outcomes.
    UNASSIGNED: We report a unique case of a patient, 5 years post-breast reconstruction following mastectomy and radiation therapy, who developed severe skin necrosis and wound dehiscence due to a brown recluse spider bite on the reconstructed breast. The complication necessitated the debridement of skin, removal of the implant, and further reconstruction with a latissimus flap.
    UNASSIGNED: The case underscores the unusual etiology of spider bite-induced necrosis in breast reconstruction and highlights the challenges and strategic considerations in managing such complications. Upon presentation, the patient\'s affected breast area showed signs of extensive necrosis and wound dehiscence, directly attributed to the cytotoxic effects of the brown recluse spider\'s venom. The venom\'s pathophysiology involves a complex cascade, leading to local and systemic effects. The local effects, marked by dermonecrosis, com- promised skin integrity in this instance. Systemic effects, not observed in this patient but potentially severe, can include hemolysis, coagulopathy, and acute renal failure, highlighting the seriousness of brown recluse spider bites.
    UNASSIGNED: In conclusion, this case illustrates the complexities of managing breast reconstruction post-mastectomy complications, particularly those caused by external factors such as brown recluse spider bites. It highlights the need for meticulous attention to unusual etiologies of necrosis and dehiscence, demonstrating the importance of adaptable surgical strategies and a thorough understanding of venom pathophysiology in ensuring successful patient outcomes.
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  • 文章类型: Letter
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  • 文章类型: Case Reports
    持续哺乳,或者半乳糖血症,是一个常见的问题,在美容手术的背景下很少见。诸如隆胸之类的美容乳房手术的频率越来越高,这表明需要更好地了解半乳糖对手术结果的影响。
    一名34岁的患者接受了日间双侧乳房缩小/乳房固定术联合肌下植入物增强术,腹部成形术和双侧侧翼吸脂术。她报告说已经停止母乳喂养超过6个月前。术中,乳腺组织被记录为泌乳。手术按计划完成,并遵循常规的术后计划,包括口服抗生素,镇痛和压缩服装。病人出院了,然而,在术后第10天因乳房疼痛和发烧而重新就诊。她接受了右乳房手术部位感染的治疗,需要冲洗和移除植入物。她被转诊到内分泌学,用溴隐亭和卡麦角林治疗半乳。随后,她接受了翻修植入增强术,效果良好。
    该病例突出了与隆胸相关的乳晕术后感染的可能性增加。在这种情况下,术前排除泌乳并避免使用假体是很重要的,将这种风险降至最低并优化手术结果。
    美容乳房外科医生必须意识到半乳糖血症的发生率,及其对术后并发症风险和不良美学结果的可能影响。作者建议在可能的情况下推迟植入直到泌乳完全解决。
    UNASSIGNED: Persistent lactation, or galactorrhoea, is a common problem which is infrequently seen in the setting of aesthetic surgery. Increasing frequency of aesthetic breast surgery such as breast augmentation suggests a need for improved understanding of the effect of galactorrhoea on surgical outcomes.
    UNASSIGNED: A 34-year-old patient underwent day-case bilateral breast reduction/mastopexy combined with sub-muscular implant augmentation, abdominoplasty and bilateral liposuction to the flanks. She reported to have stopped breastfeeding more than 6 months prior. Intraoperatively, the breast tissue was noted to be lactating. The procedure was completed as planned and a routine postoperative plan was followed including oral antibiotics, analgesia and compression garments. The patient was discharged, however reattended on postoperative day 10 with breast pain and fevers. She was treated for right breast surgical site infection and required washout and implant removal. She was referred to Endocrinology for treatment of galactorrhoea with Bromocriptine and Cabergoline. She subsequently underwent revision implant augmentation with good outcomes.
    UNASSIGNED: This case highlights the increased likelihood of post-operative infection in galactorrhoea associated with breast implant augmentation. It is important to exclude lactation preoperatively and avoid a prosthesis in this situation, to minimise this risk and optimise surgical outcomes.
    UNASSIGNED: Aesthetic breast surgeons must be aware of the incidence of galactorrhoea, and its possible effects on risks of postoperative complications and poor aesthetic outcomes. The authors suggest deferring implant augmentation until complete resolution of lactation where possible.
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    文章类型: Case Reports
    坏疽性脓皮病(PG)是一种罕见的疾病,其特征是溃疡性皮肤病变,可在术后发生,并且通常与自身免疫性疾病有关。PG是通过排除其他可能导致溃疡的疾病来诊断的,如感染,这也可能导致免疫抑制治疗延迟和伤口护理欠佳。传统上,在继发于pathergy的急性环境中避免了伤口的手术清创。本文介绍了一例广泛的乳腺PG,通过手术清创术成功治疗,猪源性细胞外基质,全身免疫抑制治疗时的负压伤口治疗。
    Pyoderma gangrenosum (PG) is a rare disease characterized by ulcerative cutaneous lesions that can occur postoperatively and is often associated with autoimmune disorders. PG is diagnosed by excluding other conditions that can cause ulcerations, such as infections, which may also result in immunosuppressive treatment delays and suboptimal wound care. Operative debridement of wounds has traditionally been avoided in the acute setting secondary to pathergy. This article presents a case of extensive breast PG that was successfully treated with surgical debridement, porcine-derived extracellular matrix, and negative pressure wound therapy while on systemic immunosuppressive therapy.
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  • 文章类型: Journal Article
    探讨Beck的认知疗法对乳房再造后患者焦虑的影响。
    本研究回顾性分析了2020年6月至2021年6月在我院接受乳房再造的150例乳腺癌患者的临床资料。排除5例未符合纳入标准的患者,将其余病例分为实验组(EG,n=70,围手术期常规管理+贝克认知疗法干预)和参照组(RG,n=75,围手术期常规管理)按照不同的围手术期干预方案,比较焦虑和抑郁的情绪,社会残疾感,两组的预后质量。
    在手术后2个月(T2)和手术后3个月(T3),EG的汉密尔顿焦虑量表(HAMA)和贝克抑郁量表(BDI)得分明显低于RG(P<0.05)。术前3天(T0)和术后1个月(T1)HAMA和BDI评分无差异(P>0.05)。在T0阶段,两组都被诊断为有社会残疾,没有明显差异(P>0.05)。在T1阶段,在T2和T3阶段,两组的社会残疾筛查计划(SDSS)得分均显着增加,而下降。在T1-T2阶段,EG的SDSS得分与RG的SDSS得分差异有统计学意义(P<0.05)。T3期差异无统计学意义(P>.05)。EG预后优良率为78.57%(55/70),高于RG的77.33%(58/75),两组无统计学差异(P<0.05)。
    对乳房再造患者实施贝克认知疗法有效改善患者的不良情绪,对促进术后康复具有重要意义,是围手术期有效的干预方案。
    UNASSIGNED: To explore the effects of Beck\'s cognitive therapy on the anxiety of patients after breast reconstruction.
    UNASSIGNED: This study retrospectively analyzed clinical data of 150 patients with breast cancer undergoing breast reconstruction from June 2020 to June 2021 in our hospital, excluded 5 patients who did not meet the inclusion criteria, divided the remaining cases into an experimental group (EG, n = 70, perioperative routine management + Beck\'s cognitive therapy intervention) and a reference group (RG, n = 75, perioperative routine management) in accordance with different perioperative intervention programs, and compared the emotions of anxiety and depression, sense of social disability, and prognosis quality in both groups.
    UNASSIGNED: At 2 months after surgery (T2) and 3 months after surgery (T3), EG had overtly lower Hamilton Anxiety Scale (HAMA) and Beck Depression Inventory (BDI) scores than RG (P < .05), with no difference in HAMA and BDI scores at 3 days before surgery (T0) and 1 month after surgery (T1) (P > .05). At the T0 stage, both groups were diagnosed as having a social disability, with no overt difference (P > .05). At T1 stage, The Social Disability Screening Schedule (SDSS) scores in both groups increased remarkably and fell back at the T2 and T3 stages. At T1-T2 stages, SDSS scores of EG were significantly different from those of RG (P < .05), with no significant difference at T3 stage (P > .05). The excellent rate of prognosis in EG was 78.57% (55/70), higher than 77.33% (58/75) in RG, with no statistical difference in both groups (P < .05).
    UNASSIGNED: The implementation of Beck\'s cognitive therapy in patients with breast reconstruction effectively improves adverse emotions in patients, which is of great significance for promoting postoperative rehabilitation and is an effective intervention program in the perioperative period.
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  • 文章类型: Case Reports
    在当今世界,对性别的概念进行了审查,对那些因出生性别和性别分类而感到不安的人的赞赏变得越来越普遍。在评估一种性别中更普遍的健康状况时,除了出生性别外,还需要记住患者的性别取向。比如乳腺癌。
    在本报告中,我们介绍了一名51岁的非洲裔美国跨性别女性,在出现新的左颈部肿块之前24年,有化学疗法和外套场放射疗法治疗锁骨下和纵隔霍奇金淋巴瘤的历史。切除肿大的淋巴结,显示出转移性唾液腺腺癌,其特征与转移性乳腺癌相对应。胸部计算机断层扫描(CT),腹部,和骨盆检测到骨盆转移和腰椎中的一些清晰的骨病变。值得注意的是,在霍奇金淋巴瘤治疗3年后,患者接受了向双乳自由注射硅胶,以强调她想要的性别.根据她的转移性疾病史和外套放射史,确定她以前的癌症诊断可能是由于通过硅胶注射掩盖的转移性乳腺癌。进行双侧保留皮肤的乳房切除术,患者恢复良好,并在随访时继续进行姑息治疗。
    尽管有关于女性和男性人群乳腺癌发病率的重要数据,文献综述显示,关于跨性别人群发病率的信息很少.我们希望这份报告将有助于文献中现有的知识基础,同时也引起人们对进一步调查跨性别者性别特异性疾病的必要性的关注。
    UNASSIGNED: In today\'s world, the concept of gender has been scrutinized and an appreciation for those who experience dysphoria with their birth sex and gender classification is becoming more commonplace. Keeping in mind the patients gender orientation in addition to their birth sex is necessary when assessing health conditions more prevalent in one sex, such as breast cancer.
    UNASSIGNED: In this report, we present a 51-year-old African American transgender female with history of chemotherapy and mantle-field radiation treatment for sub-clavicular and mediastinal Hodgkin\'s lymphoma 24 years prior to presentation of a new left neck mass. The enlarged lymph node was removed revealing metastatic salivary adenocarcinoma with features corresponding to metastatic breast carcinoma. Computed tomography (CT) of the chest, abdomen, and pelvis detected metastasis to the pelvis and a few lucent bone lesions in the lumbar spine. Of note, the patient underwent free silicone injections into both breasts to emphasize her desired gender three years after treatment for Hodgkin\'s lymphoma. Based on her history of metastatic disease and history of mantle radiation, it was determined that her previous cancer diagnoses were likely due to metastatic breast cancer that was obscured by silicone injections. Bilateral skin-sparing mastectomy was performed, patient recovered well, and continued with palliative care at follow up.
    UNASSIGNED: Even though there is significant data regarding the incidence of breast cancer in the separate female and male populations, review of the literature shows minimal information regarding incidence in the transgender population. Our hope is that this report will contribute to the current base of knowledge present in the literature while also bringing attention to the need for further investigation of sex-specific diseases in transgender individuals.
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  • 文章类型: Case Reports
    边缘性叶状肿瘤是一种罕见的良性形式的乳腺癌,具有恶性潜能。根据世界卫生组织(WHO)叶状肿瘤分为三类:良性,边界线,和恶性。在某些情况下,叶状肿瘤的治疗是广泛病灶切除结合放疗和化疗。在这里,我们报告了一名47岁的女性,她的边界质量约为19.5x16.9x9.3cm。从病史来看,我们注意到肿块在青春期开始发展。进行了广泛的病灶切除肿瘤并立即进行了基于植入物的游离乳头移植重建,与肿瘤标本测量16.5×14.2×8.7厘米。组织学检查报告有边缘性叶状肿瘤,在这种情况下,患者未接受辅助治疗.
    Borderline phyllodes tumor is a rare and benign form of breast cancer with malignant potential. According to the World Health Organization (WHO), phyllodes tumor is classified into three categories: benign, borderline, and malignant. The treatment of phyllodes tumor is wide focal excision combined with radiotherapy and chemotherapy in certain cases. Herein, we report a 47-year-old female who presented with a giant borderline mass approximately 19.5 x 16.9 x 9.3 cm in size. From medical history, we noticed that the mass begun to develop during puberty. Wide focal excision of the tumor and immediate implant-based reconstruction with free nipple graft was performed, with the tumor specimen measuring 16.5 x 14.2 x 8.7 cm. Histological examination reported a borderline phyllodes tumor, and in this case, the patient did not undergo adjuvant treatment.
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  • 文章类型: Case Reports
    在广阔的恢复性外科手术中,深下胃穿支(DIEP)皮瓣,起源于腹壁下动脉,已经成为乳房重建的首选方法,归因于其无数的优势。该技术提供了可靠的血管供应,切除的坚固组织体积,对捐赠部位的侵入性极小,直接关闭和隐藏该网站。本文对DIEP外科手术进行了详细的阐述,对诊断为早期乳腺癌的患者在立即DIEP乳房重建后发生皮瓣坏死的特殊情况进行分析探索。该患者先前曾接受过乳头乳晕复合体保留乳房切除术(NSM)。我们努力从NSM后DIEP乳房重建失败的单例病例中推断见解,并将我们的发现与DIEP乳房重建中类似手术失败的最新文献相关联。
    In the vast expanse of restorative surgical procedures, the Deep Inferior Epigastric Perforator (DIEP) flap, originating from the inferior epigastric artery, has emerged as the preferred method of breast reconstruction, attributable to its myriad advantages. The technique provides reliable vascular supply, robust tissue volume for excision, minimal invasiveness to the donor site, with direct closure and concealment of the said site. This paper embarks on an elaborate elucidation of the DIEP surgical procedure, pivoting on the analytical exploration of a particular instance where necrosis of the skin flap occurred following immediate DIEP breast reconstruction in a patient diagnosed with early-stage breast cancer. This patient had previously undergone Nipple Areola Complex Sparing Mastectomy (NSM). We endeavor to extrapolate insights from this singular case of post-NSM DIEP breast reconstruction failure and correlate our findings with current literature dedicated to similar instances of surgical failure in DIEP breast reconstruction.
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    文章类型: Case Reports
    Ehlers-Danlos综合征(EDS)是指一组遗传性结缔组织疾病(HCTDs)。EDS的临床特征包括组织脆性,关节过度活动,和皮肤过度扩张。组织脆性的后果之一是异常的伤口愈合和瘢痕形成,对治疗这些患者的外科医生构成潜在挑战。以前关于EDS患者接受乳房切除术和/或乳房再造的报道有限,并且没有患者同时诊断为血管EDS(vEDS)和经典EDS(cEDS)。
    一名41岁的女性在诊断为左乳腺小叶原位癌(LCIS)后,被转诊到整形外科诊所进行乳房重建咨询。她有cEDS和vEDS与相关胸骨的病史,胸根扩张,和超活动关节。在与病人和她的乳房外科医生共同做出决定后,决定患者将受益于双侧预防性乳腺切除术,并立即进行2期组织扩张器(TE)重建.
    此处报告的患者术后病程无明显变化。她的并发症仅限于重建第一阶段的平均出血,这很容易通过精心的术中止血来管理,术后1周出现了一个小的简单的肌下血清瘤。她在TE进行植入物交换后没有并发症,并且继续愈合良好。
    本病例报告记录了一例cEDS和vEDS患者在双侧预防性乳腺切除术并进行2期TE重建后,手术和术后病程无明显变化。
    UNASSIGNED: Ehlers-Danlos syndrome (EDS) refers to a group of heritable connective tissue disorders (HCTDs). Clinical hallmarks of EDS include tissue fragility, joint hypermobility, and skin hyperextensibility. One of the consequences of tissue fragility is abnormal wound healing and scar formation, posing potential challenges for surgeons treating these patients. There are limited previous reports of EDS patients undergoing mastectomy and/or breast reconstruction, and none wherein the patient had diagnoses of both vascular EDS (vEDS) and classical EDS (cEDS).
    UNASSIGNED: A 41-year-old female was referred to the plastic surgery clinic for breast reconstruction consultation after diagnosis of left breast lobular carcinoma in situ (LCIS). She has a past medical history of cEDS and vEDS with associated pectus carinatum, thoracic root dilation, and hypermobile joints. After shared decision making with the patient and her breast surgeon, it was decided the patient would benefit from bilateral prophylactic mastectomies with immediate 2-stage tissue expander (TE) reconstruction.
    UNASSIGNED: The patient reported here had an unremarkable postoperative course. Her complications were limited to more than average bleeding during the first stage of reconstruction, which was easily managed with meticulous intraoperative hemostasis, and a small uncomplicated submuscular seroma 1week postoperative. She had no complications following TE to implant exchange and continues to heal well.
    UNASSIGNED: This case report documents a case in which a patient with both cEDS and vEDS had an unremarkable surgical and postoperative course following bilateral prophylactic mastectomies with 2-stage TE reconstruction.
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