PDF(Pubmed)
Abstract：
UNASSIGNED: In today\'s world, the concept of gender has been scrutinized and an appreciation for those who experience dysphoria with their birth sex and gender classification is becoming more commonplace. Keeping in mind the patients gender orientation in addition to their birth sex is necessary when assessing health conditions more prevalent in one sex, such as breast cancer.
UNASSIGNED: In this report, we present a 51-year-old African American transgender female with history of chemotherapy and mantle-field radiation treatment for sub-clavicular and mediastinal Hodgkin\'s lymphoma 24 years prior to presentation of a new left neck mass. The enlarged lymph node was removed revealing metastatic salivary adenocarcinoma with features corresponding to metastatic breast carcinoma. Computed tomography (CT) of the chest, abdomen, and pelvis detected metastasis to the pelvis and a few lucent bone lesions in the lumbar spine. Of note, the patient underwent free silicone injections into both breasts to emphasize her desired gender three years after treatment for Hodgkin\'s lymphoma. Based on her history of metastatic disease and history of mantle radiation, it was determined that her previous cancer diagnoses were likely due to metastatic breast cancer that was obscured by silicone injections. Bilateral skin-sparing mastectomy was performed, patient recovered well, and continued with palliative care at follow up.
UNASSIGNED: Even though there is significant data regarding the incidence of breast cancer in the separate female and male populations, review of the literature shows minimal information regarding incidence in the transgender population. Our hope is that this report will contribute to the current base of knowledge present in the literature while also bringing attention to the need for further investigation of sex-specific diseases in transgender individuals.
UNASSIGNED: In this report, we present a 51-year-old African American transgender female with history of chemotherapy and mantle-field radiation treatment for sub-clavicular and mediastinal Hodgkin\'s lymphoma 24 years prior to presentation of a new left neck mass. The enlarged lymph node was removed revealing metastatic salivary adenocarcinoma with features corresponding to metastatic breast carcinoma. Computed tomography (CT) of the chest, abdomen, and pelvis detected metastasis to the pelvis and a few lucent bone lesions in the lumbar spine. Of note, the patient underwent free silicone injections into both breasts to emphasize her desired gender three years after treatment for Hodgkin\'s lymphoma. Based on her history of metastatic disease and history of mantle radiation, it was determined that her previous cancer diagnoses were likely due to metastatic breast cancer that was obscured by silicone injections. Bilateral skin-sparing mastectomy was performed, patient recovered well, and continued with palliative care at follow up.
UNASSIGNED: Even though there is significant data regarding the incidence of breast cancer in the separate female and male populations, review of the literature shows minimal information regarding incidence in the transgender population. Our hope is that this report will contribute to the current base of knowledge present in the literature while also bringing attention to the need for further investigation of sex-specific diseases in transgender individuals.
摘要：
■在当今世界，对性别的概念进行了审查，对那些因出生性别和性别分类而感到不安的人的赞赏变得越来越普遍。在评估一种性别中更普遍的健康状况时，除了出生性别外，还需要记住患者的性别取向。比如乳腺癌。
■在本报告中，我们介绍了一名51岁的非洲裔美国跨性别女性，在出现新的左颈部肿块之前24年，有化学疗法和外套场放射疗法治疗锁骨下和纵隔霍奇金淋巴瘤的历史。切除肿大的淋巴结，显示出转移性唾液腺腺癌，其特征与转移性乳腺癌相对应。胸部计算机断层扫描(CT),腹部，和骨盆检测到骨盆转移和腰椎中的一些清晰的骨病变。值得注意的是，在霍奇金淋巴瘤治疗3年后,患者接受了向双乳自由注射硅胶,以强调她想要的性别.根据她的转移性疾病史和外套放射史，确定她以前的癌症诊断可能是由于通过硅胶注射掩盖的转移性乳腺癌。进行双侧保留皮肤的乳房切除术，患者恢复良好,并在随访时继续进行姑息治疗。
■尽管有关于女性和男性人群乳腺癌发病率的重要数据，文献综述显示,关于跨性别人群发病率的信息很少.我们希望这份报告将有助于文献中现有的知识基础，同时也引起人们对进一步调查跨性别者性别特异性疾病的必要性的关注。
■在本报告中，我们介绍了一名51岁的非洲裔美国跨性别女性，在出现新的左颈部肿块之前24年，有化学疗法和外套场放射疗法治疗锁骨下和纵隔霍奇金淋巴瘤的历史。切除肿大的淋巴结，显示出转移性唾液腺腺癌，其特征与转移性乳腺癌相对应。胸部计算机断层扫描(CT),腹部，和骨盆检测到骨盆转移和腰椎中的一些清晰的骨病变。值得注意的是，在霍奇金淋巴瘤治疗3年后,患者接受了向双乳自由注射硅胶,以强调她想要的性别.根据她的转移性疾病史和外套放射史，确定她以前的癌症诊断可能是由于通过硅胶注射掩盖的转移性乳腺癌。进行双侧保留皮肤的乳房切除术，患者恢复良好,并在随访时继续进行姑息治疗。
■尽管有关于女性和男性人群乳腺癌发病率的重要数据，文献综述显示,关于跨性别人群发病率的信息很少.我们希望这份报告将有助于文献中现有的知识基础，同时也引起人们对进一步调查跨性别者性别特异性疾病的必要性的关注。
