PDF(Pubmed)
Abstract：
Pyoderma gangrenosum (PG) is a rare disease characterized by ulcerative cutaneous lesions that can occur postoperatively and is often associated with autoimmune disorders. PG is diagnosed by excluding other conditions that can cause ulcerations, such as infections, which may also result in immunosuppressive treatment delays and suboptimal wound care. Operative debridement of wounds has traditionally been avoided in the acute setting secondary to pathergy. This article presents a case of extensive breast PG that was successfully treated with surgical debridement, porcine-derived extracellular matrix, and negative pressure wound therapy while on systemic immunosuppressive therapy.
摘要：
坏疽性脓皮病（PG）是一种罕见的疾病，其特征是溃疡性皮肤病变，可在术后发生，并且通常与自身免疫性疾病有关。PG是通过排除其他可能导致溃疡的疾病来诊断的，如感染，这也可能导致免疫抑制治疗延迟和伤口护理欠佳。传统上，在继发于pathergy的急性环境中避免了伤口的手术清创。本文介绍了一例广泛的乳腺PG，通过手术清创术成功治疗，猪源性细胞外基质，全身免疫抑制治疗时的负压伤口治疗。
