目标:随着年龄的增长,睡眠阶段和特征随着时间的推移而转变,但是睡眠不足会严重影响健康和认知功能。慢性睡眠不足与注意力和生产力受损有关,免疫力减弱,心血管疾病的风险增加,肥胖,和精神健康障碍。失眠,阻塞性睡眠呼吸暂停综合征,荷尔蒙的变化,夜尿症,神经系统疾病,和生活事件会干扰睡眠模式,有些与下尿路症状(LUTS)有关。这个关于终身LUTS的NOPIA研讨会旨在分析关于睡眠和LUTS之间关联的文献,为未来的研究产生想法,并探讨在整个生命周期中,与睡眠变化有关的终身LUTS的概念是否得到支持。
方法:一个国际专家小组参加了由NOPIA研究小组组织的在线会议,讨论终身LUTS在睡眠和大脑关系中的作用。手稿总结了现有文献,假设,未来的研究思路,和临床建议。
结果:失眠,睡眠碎片,过度觉醒,和感觉加工障碍成为睡眠和LUTS之间关系的潜在因素。失眠通常是一个持续的因素,可能是最初的症状;然而,在医疗保健环境中通常无法识别和/或无法解决。通过认识到失眠是各种健康问题的主要驱动因素,包括夜尿症,过渡护理旨在尽早解决根本原因和潜在问题,以启动适当的治疗。
结论:多学科的方法,包括不同学科的医疗保健专业人员之间的合作,比如泌尿科,睡眠医学,妇科,儿科,和老年医学,是必要的,应该包括经过验证的测量,如失眠严重程度指数和睡眠和排尿日记。确保通过过渡性护理进行持续的随访和监测对于患有持续性睡眠问题和LUTS的个人至关重要。允许在生命周期中出现或波动的问题得到解决。
OBJECTIVE: As people age, sleep stages and characteristics transition over time, but sleep deficits can profoundly impact health and cognitive functioning. Chronic sleep deprivation is linked to impaired attention and productivity, weakened immunity, increased risk of cardiovascular disease, obesity, and mental health disorders. Insomnia, obstructive sleep apnea syndrome, hormonal changes, nocturia, neurological disorders, and life events interfere with sleep patterns and some are linked to lower urinary tract symptoms (LUTS). This NOPIA symposium on Lifelong LUTS aimed to analyze the literature on associations between sleep and LUTS, generate ideas for future research, and explore whether there is support for the concept of lifelong LUTS in relation to changes in sleep throughout the lifespan.
METHODS: An international panel of experts took part in an online meeting addressing the role of lifelong LUTS in relationship to sleep and the brain organized by the NOPIA research group. The manuscript summarizes existing literature, hypotheses, future research ideas, and clinical recommendations.
RESULTS: Insomnia, sleep fragmentation, hyperarousal, and sensory processing disorders emerged as potential factors in the relationship between sleep and LUTS. Insomnia is often a persistent factor and may have been the initial symptom; however, it is often unrecognized and/or unaddressed in healthcare settings. By recognizing insomnia as a primary driver of various health issues, including nocturia, transitional care aims to address root causes and underlying problems earlier to initiate appropriate treatment.
CONCLUSIONS: A multidisciplinary approach with collaboration between healthcare professionals from various disciplines, such as urology, sleep medicine, gynecology, pediatrics, and geriatrics, is needed and should include validated measurements such as the insomnia severity index and sleep and voiding diaries. Ensuring ongoing follow-up and monitoring through transitional care is crucial for individuals with persistent sleep problems and LUTS, allowing issues that arise or fluctuate over the lifespan to be addressed.