Abstract：
The sleep quality of lowlanders in hypoxic environments has become increasingly important with an increase in highland and alpine activities. This study aimed to identify the effects of acute exposure to hypoxia on the sleep structure of lowlanders and to analyze the changes in sleep indicators at varying levels of hypoxia. This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Twenty-three studies were screened and included in the quantitative analysis. The results showed that acute exposure to hypoxia reduced sleep quality in lowlanders. Post-sleep arousal events and the percentage of N1 were significantly increased, whereas total sleep time, sleep efficiency, and the percentage of N3 and rapid eye movement sleep were significantly decreased in hypoxic environments. Acute exposure to hypoxia had the greatest negative impact on wakefulness after sleep onset (WASO). In addition, a larger decrease in sleep efficiency and higher increase in the percentages of N1 and WASO were observed when lowlanders were exposed to higher levels of hypoxia. This study clarifies the quantitative effects of acute hypoxic exposure on sleep in lowlanders based on original studies and explains the sleep disorders faced by lowlanders in hypoxic environments.
摘要：
随着高原和高山活动的增加，低氧环境中低地人的睡眠质量变得越来越重要。本研究旨在确定急性低氧暴露对低地居民睡眠结构的影响，并分析不同低氧水平下睡眠指标的变化。这项审查是根据系统审查和荟萃分析指南的首选报告项目进行的。筛选了23项研究并纳入定量分析。结果表明，急性缺氧会降低低地居民的睡眠质量。睡眠后唤醒事件和N1的百分比显着增加，而总睡眠时间，睡眠效率，在低氧环境下，N3和快速眼动睡眠的百分比显着降低。急性缺氧对睡眠发作（WASO）后的觉醒有最大的负面影响。此外,当低地人群暴露于较高水平的缺氧时,观察到睡眠效率下降幅度更大,N1和WASO百分比增加幅度更大.这项研究根据原始研究阐明了急性低氧暴露对低地居民睡眠的定量影响，并解释了低氧环境下低地居民面临的睡眠障碍。
