来自农业工业废物的活性成分的潜在潜力仍未开发,并提供了大量未开发的资源。虽然这些类型的材料在各个领域都有应用,它们有益于人类健康的能力需要进一步探索和调查。本系统综述旨在系统地评估非临床研究,这些研究研究了馏分的生物学效应,来自农业工业废物的提取物和生物活性化合物及其潜在的治疗应用。文章是通过PubMed选择的,Embase和Medline使用描述符(副产品[标题/摘要])和(农用工业[标题/摘要])。系统评价在国际前瞻性系统评价登记册(Prospero)中注册,编号为CRD42024491021。在根据纳入和排除标准进行详细分析后,共38篇文章用于数据提取和结果讨论。从研究来自农业工业的各种残留物的体外和体内实验中发现了信息。这些研究调查了果皮,果渣/甘蔗渣,纸浆,种子,天线部件,谷物/谷物和其他类型的废物。研究最多的活性主要包括抗氧化和抗炎作用,但其他活动,如抗菌,细胞毒性,抗增殖,抗伤害性,低血糖,还描述了抗高血糖和抗凝血作用。最后,这篇综述中包含的研究证明了农业工业废物的潜力,并可以推动未来的研究,重点是临床应用.
The latent potential of active ingredients derived from agro-industrial waste remains largely untapped and offers a wealth of unexplored resources. While these types of materials have applications in various fields, their ability to benefit human health needs to be further explored and investigated. This systematic
review was conducted to systematically evaluate non-clinical studies that have investigated the biological effects of fractions, extracts and bioactive compounds from agro-industrial wastes and their potential therapeutic applications. Articles were selected via PubMed, Embase and Medline using the descriptors (by-products[title/abstract]) AND (agro-industrial[title/abstract]). The systematic
review was registered in the International Prospective Register of Systematic Reviews (Prospero) under the number CRD42024491021. After a detailed analysis based on inclusion and exclusion criteria, a total of 38 articles were used for data extraction and discussion of the results. Information was found from in vitro and in vivo experiments investigating a variety of residues from the agro-industry. The studies investigated peels, pomace/bagasse, pulp, seeds, aerial parts, cereals/grains and other types of waste. The most studied activities include mainly antioxidant and anti-inflammatory effects, but other activities such as antimicrobial, cytotoxic, antiproliferative, antinociceptive, hypoglycemic, antihyperglycemic and anticoagulant effects have also been described. Finally, the studies included in this
review demonstrate the potential of agro-industrial waste and can drive future research with a focus on clinical application.