Abstract：
METHODS: Electroconvulsive therapy (ECT) is a commonly used treatment for severe psychiatric illness in older adults, including in the \'older old\' population aged 80 years and above. However, there can sometimes be a reluctance to treat the 80+ year old age group with ECT due to medical comorbidities, frailty, and concerns about cognition.
UNASSIGNED: This multi-site, longitudinal Australian study aimed to investigate the effectiveness and safety of ECT in older old people compared with younger age groups. Data from 310 people receiving ECT for depression at three participating hospitals was collected in a naturalistic setting, between 2015 and 2022.
METHODS: Clinical ratings were conducted pre-ECT and end-acute ECT using the Montgomery-Åsberg Depression Rating Scale (MADRS). Cognitive outcomes were assessed using the Montreal Cognitive Assessment (MoCA).
RESULTS: Older old adults demonstrated a significant reduction MADRS scores at post-treatment. They were more likely to meet remission criteria compared with the younger age groups. Older old adults were also less likely to show clinically significant cognitive decline post-ECT, and were more likely to show clinically significant cognitive improvement post-ECT compared with younger age groups.
CONCLUSIONS: ECT is highly effective in treating severe psychiatric illness in older old adults. Relative to the younger age groups, the older old group were more likely to remit with ECT and a greater proportion showed cognitive improvement post-ECT. These findings suggest that ECT should be considered as a valuable and safe treatment option for older old individuals with depression.
UNASSIGNED: This multi-site, longitudinal Australian study aimed to investigate the effectiveness and safety of ECT in older old people compared with younger age groups. Data from 310 people receiving ECT for depression at three participating hospitals was collected in a naturalistic setting, between 2015 and 2022.
METHODS: Clinical ratings were conducted pre-ECT and end-acute ECT using the Montgomery-Åsberg Depression Rating Scale (MADRS). Cognitive outcomes were assessed using the Montreal Cognitive Assessment (MoCA).
RESULTS: Older old adults demonstrated a significant reduction MADRS scores at post-treatment. They were more likely to meet remission criteria compared with the younger age groups. Older old adults were also less likely to show clinically significant cognitive decline post-ECT, and were more likely to show clinically significant cognitive improvement post-ECT compared with younger age groups.
CONCLUSIONS: ECT is highly effective in treating severe psychiatric illness in older old adults. Relative to the younger age groups, the older old group were more likely to remit with ECT and a greater proportion showed cognitive improvement post-ECT. These findings suggest that ECT should be considered as a valuable and safe treatment option for older old individuals with depression.
摘要：
方法：电惊厥疗法（ECT）是老年人严重精神疾病的常用治疗方法，包括80岁及以上的老年人口。然而,由于医疗合并症，有时可能不愿意用ECT治疗80岁以上的年龄组，脆弱,以及对认知的担忧。
■这个多站点，澳大利亚纵向研究旨在调查老年人与年轻年龄组相比ECT的有效性和安全性。在自然环境中收集了在三家参与医院接受ECT治疗抑郁症的310人的数据，2015年至2022年。
方法：使用蒙哥马利-奥斯贝格抑郁量表（MADRS）进行ECT前和急性终末期ECT的临床评分。使用蒙特利尔认知评估（MoCA）评估认知结果。
结果：老年患者治疗后MADRS评分显著降低。与年轻年龄组相比，他们更有可能达到缓解标准。老年人也不太可能在ECT后表现出临床上显著的认知能力下降，与年轻年龄组相比，ECT后更有可能显示出临床上显著的认知改善。
结论：ECT在治疗老年人的严重精神疾病方面非常有效。相对于年轻的年龄组，年龄较大的老年组更有可能接受ECT治疗,ECT后认知功能改善的比例更高.这些发现表明，ECT应被视为老年抑郁症患者的一种有价值且安全的治疗选择。
■这个多站点，澳大利亚纵向研究旨在调查老年人与年轻年龄组相比ECT的有效性和安全性。在自然环境中收集了在三家参与医院接受ECT治疗抑郁症的310人的数据，2015年至2022年。
方法：使用蒙哥马利-奥斯贝格抑郁量表（MADRS）进行ECT前和急性终末期ECT的临床评分。使用蒙特利尔认知评估（MoCA）评估认知结果。
结果：老年患者治疗后MADRS评分显著降低。与年轻年龄组相比，他们更有可能达到缓解标准。老年人也不太可能在ECT后表现出临床上显著的认知能力下降，与年轻年龄组相比，ECT后更有可能显示出临床上显著的认知改善。
结论：ECT在治疗老年人的严重精神疾病方面非常有效。相对于年轻的年龄组，年龄较大的老年组更有可能接受ECT治疗,ECT后认知功能改善的比例更高.这些发现表明，ECT应被视为老年抑郁症患者的一种有价值且安全的治疗选择。
