PDF(Pubmed)
Abstract：
UNASSIGNED: Sexual transmission among men who have sex with men (MSM) has become the major HIV transmission route. However, limited research has been conducted to investigate the association between transactional sex (TS) and HIV incidence in China.
UNASSIGNED: This study aims to investigate HIV incidence and distinguish sociodemographic and sexual behavioral risk factors associated with HIV incidence among MSM who engage in TS (MSM-TS) in China.
UNASSIGNED: We conducted a prospective cohort study using a WeChat-based platform to evaluate HIV incidence among Chinese MSM, including MSM-TS in Ningbo, recruited from July 2019 until June 2022. At each visit, participants completed a questionnaire and scheduled an appointment for HIV counseling and testing on the WeChat-based platform before undergoing offline HIV tests. HIV incidence density was calculated as the number of HIV seroconversions divided by person-years (PYs) of follow-up, and univariate and multivariate Cox proportional hazards regression was conducted to identify factors associated with HIV incidence.
UNASSIGNED: A total of 932 participants contributed 630.9 PYs of follow-up, and 25 HIV seroconversions were observed during the study period, resulting in an estimated HIV incidence of 4.0 (95% CI 2.7-5.8) per 100 PYs. The HIV incidence among MSM-TS was 18.4 (95% CI 8.7-34.7) per 100 PYs, which was significantly higher than the incidence of 3.2 (95% CI 2.1-5.0) per 100 PYs among MSM who do not engage in TS. After adjusting for sociodemographic characteristics, factors associated with HIV acquisition were MSM-TS (adjusted hazard ratio [aHR] 3.93, 95% CI 1.29-11.93), having unprotected sex with men (aHR 10.35, 95% CI 2.25-47.69), and having multiple male sex partners (aHR 3.43, 95% CI 1.22-9.64) in the past 6 months.
UNASSIGNED: This study found a high incidence of HIV among MSM-TS in Ningbo, China. The risk factors associated with HIV incidence include TS, having unprotected sex with men, and having multiple male sex partners. These findings emphasize the need for developing targeted interventions and providing comprehensive medical care, HIV testing, and preexposure prophylaxis for MSM, particularly those who engage in TS.
UNASSIGNED: This study aims to investigate HIV incidence and distinguish sociodemographic and sexual behavioral risk factors associated with HIV incidence among MSM who engage in TS (MSM-TS) in China.
UNASSIGNED: We conducted a prospective cohort study using a WeChat-based platform to evaluate HIV incidence among Chinese MSM, including MSM-TS in Ningbo, recruited from July 2019 until June 2022. At each visit, participants completed a questionnaire and scheduled an appointment for HIV counseling and testing on the WeChat-based platform before undergoing offline HIV tests. HIV incidence density was calculated as the number of HIV seroconversions divided by person-years (PYs) of follow-up, and univariate and multivariate Cox proportional hazards regression was conducted to identify factors associated with HIV incidence.
UNASSIGNED: A total of 932 participants contributed 630.9 PYs of follow-up, and 25 HIV seroconversions were observed during the study period, resulting in an estimated HIV incidence of 4.0 (95% CI 2.7-5.8) per 100 PYs. The HIV incidence among MSM-TS was 18.4 (95% CI 8.7-34.7) per 100 PYs, which was significantly higher than the incidence of 3.2 (95% CI 2.1-5.0) per 100 PYs among MSM who do not engage in TS. After adjusting for sociodemographic characteristics, factors associated with HIV acquisition were MSM-TS (adjusted hazard ratio [aHR] 3.93, 95% CI 1.29-11.93), having unprotected sex with men (aHR 10.35, 95% CI 2.25-47.69), and having multiple male sex partners (aHR 3.43, 95% CI 1.22-9.64) in the past 6 months.
UNASSIGNED: This study found a high incidence of HIV among MSM-TS in Ningbo, China. The risk factors associated with HIV incidence include TS, having unprotected sex with men, and having multiple male sex partners. These findings emphasize the need for developing targeted interventions and providing comprehensive medical care, HIV testing, and preexposure prophylaxis for MSM, particularly those who engage in TS.
摘要：
■男男性行为者（MSM）之间的性传播已成为主要的HIV传播途径。然而,在中国，已经进行了有限的研究来调查交易性行为（TS）与HIV发病率之间的关系。
■本研究旨在调查在中国从事TS（MSM-TS）的MSM中的HIV发病率，并区分与HIV发病率相关的社会人口统计学和性行为危险因素。
■我们使用基于微信的平台进行了一项前瞻性队列研究，以评估中国MSM的HIV发病率。包括宁波的MSM-TS，从2019年7月至2022年6月招募。每次访问,参与者在接受线下HIV检测之前,在微信平台上完成了一份问卷并预约了HIV咨询和检测.HIV发病率密度计算为HIV血清转化数除以随访的人年（PYs），进行单因素和多因素Cox比例风险回归,以确定与HIV发病率相关的因素.
■共有932名参与者贡献了630.9个PYs的随访，在研究期间观察到25例HIV血清转化，导致每100个PYs的HIV发病率估计为4.0（95%CI2.7-5.8）。MSM-TS中的HIV发病率为每100个PYs18.4（95％CI8.7-34.7），显着高于不从事TS的MSM中每100个PYs3.2（95％CI2.1-5.0）的发生率。在调整了社会人口统计学特征后，与HIV感染相关的因素是MSM-TS(调整后的风险比[AHR]3.93，95%CI1.29-11.93)，与男性发生无保护性行为（aHR10.35，95%CI2.25-47.69），并且在过去6个月中有多个男性性伴侣（aHR3.43，95％CI1.22-9.64）。
■这项研究发现，宁波的MSM-TS中HIV的发病率很高，中国。与艾滋病毒发病率相关的危险因素包括TS，与男人发生无保护的性行为,有多个男性性伴侣.这些发现强调需要制定有针对性的干预措施，并提供全面的医疗服务，艾滋病毒检测,和MSM的暴露前预防，特别是那些从事TS的人。
■本研究旨在调查在中国从事TS（MSM-TS）的MSM中的HIV发病率，并区分与HIV发病率相关的社会人口统计学和性行为危险因素。
■我们使用基于微信的平台进行了一项前瞻性队列研究，以评估中国MSM的HIV发病率。包括宁波的MSM-TS，从2019年7月至2022年6月招募。每次访问,参与者在接受线下HIV检测之前,在微信平台上完成了一份问卷并预约了HIV咨询和检测.HIV发病率密度计算为HIV血清转化数除以随访的人年（PYs），进行单因素和多因素Cox比例风险回归,以确定与HIV发病率相关的因素.
■共有932名参与者贡献了630.9个PYs的随访，在研究期间观察到25例HIV血清转化，导致每100个PYs的HIV发病率估计为4.0（95%CI2.7-5.8）。MSM-TS中的HIV发病率为每100个PYs18.4（95％CI8.7-34.7），显着高于不从事TS的MSM中每100个PYs3.2（95％CI2.1-5.0）的发生率。在调整了社会人口统计学特征后，与HIV感染相关的因素是MSM-TS(调整后的风险比[AHR]3.93，95%CI1.29-11.93)，与男性发生无保护性行为（aHR10.35，95%CI2.25-47.69），并且在过去6个月中有多个男性性伴侣（aHR3.43，95％CI1.22-9.64）。
■这项研究发现，宁波的MSM-TS中HIV的发病率很高，中国。与艾滋病毒发病率相关的危险因素包括TS，与男人发生无保护的性行为,有多个男性性伴侣.这些发现强调需要制定有针对性的干预措施，并提供全面的医疗服务，艾滋病毒检测,和MSM的暴露前预防，特别是那些从事TS的人。
