Abstract：
Innately designed to induce physiological changes, pharmaceuticals are foreknowingly hazardous to the ecosystem. Advanced oxidation processes (AOPs) are recognized as a set of contemporary and highly efficient methods being used as a contrivance for the removal of pharmaceutical residues. Since reactive oxygen species (ROS) are formed in these processes to interact and contribute directly toward the oxidation of target contaminant(s), a profound insight regarding the mechanisms of ROS leading to the degradation of pharmaceuticals is fundamentally significant. The conceptualization of some specific reaction mechanisms allows the design of an effective and safe degradation process that can empirically reduce the environmental impact of the micropollutants. This review mainly deliberates the mechanistic reaction pathways for ROS-mediated degradation of pharmaceuticals often leading to complete mineralization, with a focus on acetaminophen as a drug waste model.
摘要：
天生旨在诱导生理变化，药物对生态系统是有害的。高级氧化工艺（AOP）被认为是一组现代且高效的方法，可用作去除药物残留物的发明。由于活性氧（ROS）在这些过程中形成相互作用并直接促进目标污染物的氧化，关于ROS导致药物降解的机制的深刻见解具有根本意义。一些特定反应机理的概念化允许设计有效且安全的降解过程，该过程可以凭经验减少微污染物的环境影响。这篇综述主要讨论了ROS介导的药物降解的机理反应途径，通常会导致完全矿化，专注于对乙酰氨基酚作为药物废物模型。
