关键词: Exposure Food PFAS Risk assessment

Mesh : Italy Fluorocarbons / analysis Humans Risk Assessment Adult Alkanesulfonic Acids / analysis Adolescent Caprylates / analysis Middle Aged Food Contamination Water Pollutants, Chemical / analysis Aged Dietary Exposure / analysis Young Adult Environmental Monitoring Female Sulfonic Acids

来  源:   DOI:10.19191/EP24.3.A770.060

Abstract:
The Veneto Region (Northern Italy) conducted a monitoring campaign in the years 2016-2017 in order to evaluate the concentration of per- and polyfluoroalkyl substances (PFASs) in foods in the area affected by the water contamination discovered in 2013. The risk assessment for the resident population was conducted by the Italian National Institute of Health (ISS) in 2018 and updated in 2021. The European Food Safety Agency (EFSA) updated the limits used by ISS, in particular adding a limit for the sum of four PFAS molecules in 2020. In this work, the risk assessment conducted by ISS is reviewed in light of the new limit of 4.4 ng/kg body weight for the sum of perfluorooctanoic acid (PFOA), perfluorooctanesulfonic acid (PFOS), perfluorononanoic acid (PFNA), and perfluorohexanesulfonate (PFHxS). In the adult population (18-65 years), total weekly intakes, calculated for the years preceding 2013, resulted more than ten times the EFSA 2020 limit, more than five times in the intermediate period 2013-2017 - preceding the implementation of mitigation actions through double filtration of the water of the aqueduct -, by more than three times in the period after 2018, and yet by almost seven times for those who supply contaminated groundwater through private wells. The food contribution for those who use filtered water from the aqueduct is equal to 20% of the total weekly income.
摘要:
威尼托地区(意大利北部)在2016-2017年开展了一项监测活动,以评估受2013年发现的水污染影响地区食品中全氟烷基物质和多氟烷基物质(PFAS)的浓度。常住人口的风险评估由意大利国家卫生研究所(ISS)于2018年进行,并于2021年进行了更新。欧洲食品安全局(EFSA)更新了ISS使用的限值,特别是在2020年增加了四个PFAS分子总和的限制。在这项工作中,根据全氟辛酸(PFOA)总量为4.4ng/kg体重的新限值,对ISS进行的风险评估进行了审查,全氟辛烷磺酸(PFOS),全氟壬酸(PFNA),和全氟己烷磺酸盐(PFHxS)。在成年人(18-65岁)中,每周总摄入量,按2013年之前的几年计算,导致EFSA2020年限制的十倍以上,在通过对渡槽的水进行双重过滤实施缓解行动之前,在2013-2017年中期超过五倍,在2018年之后的时间里,这一比例是过去的三倍多,而那些通过私人水井供应受污染地下水的人的比例则提高了近七倍。使用渡槽过滤水的人的食物贡献等于每周总收入的20%。
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