PDF(Pubmed)
Abstract：
UNASSIGNED: Stress is one of the main environmental factors involved in the onset of different psychopathologies. In youth, stressful life events can trigger inappropriate and health-damaging behaviors, such as binge drinking. This behavior, in turn, can lead to long-lasting changes in the neurophysiological response to stress and the development of psychological disorders late in life, e.g., alcohol use disorder. Our aim was to analyze the pattern of neurophysiological responses triggered with the exposition to a stressful virtual environment in young binge drinkers.
UNASSIGNED: AUDIT-3 (third question from the full AUDIT) was used to detect binge drinking (BD) in our young sample (age 18-25 years). According to the score, participants were divided into control (CO) and BD group. Next, a standardized virtual reality (VR) scenario (Richie\'s Plank) was used for triggering the stress response while measuring the following neurophysiological variables: brain electrical activity by electroencephalogram (EEG) and cortisol levels through saliva samples both measurements registered before and after the stressful situation. Besides, heart rate (HR) with a pulsometer and electrodermal response (EDA) through electrodes placed on fingers were analyzed before, during and after the VR task.
UNASSIGNED: Regarding the behavior assessed during the VR task, BD group spent significantly less amount of time walking forward the table and a tendency toward more time walking backwards. There was no statistically significant difference between the BD and the CO group regarding time looking down, but when we controlled the variable sex, the BD women group displayed higher amount of time looking down than the rest of the groups. Neurophysiological measurements revealed that there was not any statistically significant difference between groups in any of the EEG registered measures, EDA response and cortisol levels. Sex-related differences were found in HR response to VR scenario, in which BD women displayed the highest peak of response to the stressor. Also, the change in heartbeat was higher in BD women than men.
UNASSIGNED: Unveiling the neurophysiological alterations associated with BD can help us to prevent and detect early onset of alcohol use disorder. Also, from our data we conclude that participants\' sex can modulate some stress responses, especially when unhealthy behaviors such as BD are present. Nevertheless, the moment of registration of the neurophysiological variables respect to the stressor seems to be a crucial variable.
UNASSIGNED: AUDIT-3 (third question from the full AUDIT) was used to detect binge drinking (BD) in our young sample (age 18-25 years). According to the score, participants were divided into control (CO) and BD group. Next, a standardized virtual reality (VR) scenario (Richie\'s Plank) was used for triggering the stress response while measuring the following neurophysiological variables: brain electrical activity by electroencephalogram (EEG) and cortisol levels through saliva samples both measurements registered before and after the stressful situation. Besides, heart rate (HR) with a pulsometer and electrodermal response (EDA) through electrodes placed on fingers were analyzed before, during and after the VR task.
UNASSIGNED: Regarding the behavior assessed during the VR task, BD group spent significantly less amount of time walking forward the table and a tendency toward more time walking backwards. There was no statistically significant difference between the BD and the CO group regarding time looking down, but when we controlled the variable sex, the BD women group displayed higher amount of time looking down than the rest of the groups. Neurophysiological measurements revealed that there was not any statistically significant difference between groups in any of the EEG registered measures, EDA response and cortisol levels. Sex-related differences were found in HR response to VR scenario, in which BD women displayed the highest peak of response to the stressor. Also, the change in heartbeat was higher in BD women than men.
UNASSIGNED: Unveiling the neurophysiological alterations associated with BD can help us to prevent and detect early onset of alcohol use disorder. Also, from our data we conclude that participants\' sex can modulate some stress responses, especially when unhealthy behaviors such as BD are present. Nevertheless, the moment of registration of the neurophysiological variables respect to the stressor seems to be a crucial variable.
摘要：
■压力是参与不同精神病理学发作的主要环境因素之一。在青年时期,紧张的生活事件会引发不适当的和损害健康的行为，比如暴饮暴食。这种行为,反过来,会导致对压力的神经生理反应的持久变化和晚年心理障碍的发展，例如，酒精使用障碍。我们的目的是分析年轻暴饮暴食者对紧张的虚拟环境的阐述引发的神经生理反应模式。
■AUDIT-3（来自完整AUDIT的第三个问题）用于检测我们年轻样本（年龄18-25岁）中的暴饮暴食（BD）。根据分数,参与者分为对照组(CO)和BD组。接下来,使用标准化的虚拟现实（VR）场景（Richie'sPlank）触发应激反应，同时测量以下神经生理变量：通过脑电图（EEG）进行的脑电活动和通过唾液样本进行的皮质醇水平，这两个测量值在压力状况之前和之后进行记录。此外,心率（HR）与脉搏计和皮肤电反应（EDA）通过电极放置在手指之前进行分析，在VR任务期间和之后。
■关于VR任务期间评估的行为，BD组花在向前走桌子上的时间明显减少，并且倾向于向后走更多的时间。BD组和CO组的观察时间没有统计学差异,但是当我们控制可变性别时，BD女性组比其他组显示更多的向下看的时间。神经生理学测量显示，在任何EEG注册测量中，组间没有任何统计学上的显着差异，EDA反应和皮质醇水平。在对VR场景的HR反应中发现了与性别相关的差异，其中BD女性对压力源的反应达到最高峰。此外，BD女性的心跳变化高于男性。
■揭示与BD相关的神经生理改变可以帮助我们预防和发现酒精使用障碍的早期发作。此外，根据我们的数据，我们得出结论，参与者的性行为可以调节一些应激反应，特别是当不健康的行为，如BD存在。然而，神经生理变量相对于压力源的注册时刻似乎是至关重要的变量。
■AUDIT-3（来自完整AUDIT的第三个问题）用于检测我们年轻样本（年龄18-25岁）中的暴饮暴食（BD）。根据分数,参与者分为对照组(CO)和BD组。接下来,使用标准化的虚拟现实（VR）场景（Richie'sPlank）触发应激反应，同时测量以下神经生理变量：通过脑电图（EEG）进行的脑电活动和通过唾液样本进行的皮质醇水平，这两个测量值在压力状况之前和之后进行记录。此外,心率（HR）与脉搏计和皮肤电反应（EDA）通过电极放置在手指之前进行分析，在VR任务期间和之后。
■关于VR任务期间评估的行为，BD组花在向前走桌子上的时间明显减少，并且倾向于向后走更多的时间。BD组和CO组的观察时间没有统计学差异,但是当我们控制可变性别时，BD女性组比其他组显示更多的向下看的时间。神经生理学测量显示，在任何EEG注册测量中，组间没有任何统计学上的显着差异，EDA反应和皮质醇水平。在对VR场景的HR反应中发现了与性别相关的差异，其中BD女性对压力源的反应达到最高峰。此外，BD女性的心跳变化高于男性。
■揭示与BD相关的神经生理改变可以帮助我们预防和发现酒精使用障碍的早期发作。此外，根据我们的数据，我们得出结论，参与者的性行为可以调节一些应激反应，特别是当不健康的行为，如BD存在。然而，神经生理变量相对于压力源的注册时刻似乎是至关重要的变量。
