PDF(Pubmed)
Abstract：
BACKGROUND: Respiratory Syncytial Virus (RSV) is a leading cause of acute lower respiratory infection in children worldwide. Understanding its prevalence, variations, and characteristics is vital, particularly in the context of the COVID-19 pandemic.
OBJECTIVE: The study aimed to investigate the RSV positivity rate, subtype prevalence, age and gender distribution, symptomatology, and co-infection rates during pre-pandemic and pandemic periods.
METHODS: We analyzed data from 15,381 patients tested for RSV between 2017 and 2023.
RESULTS: Our analysis revealed a 7.2% average RSV positivity rate in the pre-pandemic period, with significant fluctuations during the pandemic (1.5% in 2020 to 32.0% in 2021). We observed variations in RSVA and RSVB detection rates. The 0-4 years\' age group was consistently the most affected, with a slight male predominance. Fever and cough were common symptoms. Therapeutic interventions, particularly antiviral usage and ventilation requirements, decreased during the pandemic. We also identified variations in co-infection rates with other respiratory viruses.
CONCLUSIONS: Our study offers critical insights into the impact of the COVID-19 pandemic on RSV prevalence, subtype distribution, patient characteristics, and clinical management. These findings underscore the need for ongoing surveillance and adaptive public health responses.
OBJECTIVE: The study aimed to investigate the RSV positivity rate, subtype prevalence, age and gender distribution, symptomatology, and co-infection rates during pre-pandemic and pandemic periods.
METHODS: We analyzed data from 15,381 patients tested for RSV between 2017 and 2023.
RESULTS: Our analysis revealed a 7.2% average RSV positivity rate in the pre-pandemic period, with significant fluctuations during the pandemic (1.5% in 2020 to 32.0% in 2021). We observed variations in RSVA and RSVB detection rates. The 0-4 years\' age group was consistently the most affected, with a slight male predominance. Fever and cough were common symptoms. Therapeutic interventions, particularly antiviral usage and ventilation requirements, decreased during the pandemic. We also identified variations in co-infection rates with other respiratory viruses.
CONCLUSIONS: Our study offers critical insights into the impact of the COVID-19 pandemic on RSV prevalence, subtype distribution, patient characteristics, and clinical management. These findings underscore the need for ongoing surveillance and adaptive public health responses.
摘要：
背景：呼吸道合胞病毒（RSV）是全球儿童急性下呼吸道感染的主要原因。了解其普遍性，变体,特征是至关重要的，特别是在COVID-19大流行的背景下。
目的：本研究旨在调查RSV阳性率，亚型患病率,年龄和性别分布，症状学，大流行前和大流行期间的合并感染率。
方法：我们分析了2017年至2023年接受RSV测试的15381例患者的数据。
结果：我们的分析显示，在大流行前，RSV的平均阳性率为7.2%，大流行期间波动显著（2020年为1.5%，2021年为32.0%）。我们观察到RSVA和RSVB检出率的变化。0-4岁年龄组一直受影响最严重，有轻微的男性优势。发热和咳嗽是常见症状。治疗干预措施，特别是抗病毒的使用和通风要求，在大流行期间减少。我们还确定了与其他呼吸道病毒共感染率的差异。
结论：我们的研究提供了关于COVID-19大流行对RSV流行影响的重要见解，亚型分布，患者特征,和临床管理。这些发现强调了持续监测和适应性公共卫生对策的必要性。
目的：本研究旨在调查RSV阳性率，亚型患病率,年龄和性别分布，症状学，大流行前和大流行期间的合并感染率。
方法：我们分析了2017年至2023年接受RSV测试的15381例患者的数据。
结果：我们的分析显示，在大流行前，RSV的平均阳性率为7.2%，大流行期间波动显著（2020年为1.5%，2021年为32.0%）。我们观察到RSVA和RSVB检出率的变化。0-4岁年龄组一直受影响最严重，有轻微的男性优势。发热和咳嗽是常见症状。治疗干预措施，特别是抗病毒的使用和通风要求，在大流行期间减少。我们还确定了与其他呼吸道病毒共感染率的差异。
结论：我们的研究提供了关于COVID-19大流行对RSV流行影响的重要见解，亚型分布，患者特征,和临床管理。这些发现强调了持续监测和适应性公共卫生对策的必要性。
