PDF(Pubmed)
Abstract：
Europe has suffered unprecedented epizootics of high pathogenicity avian influenza (HPAI) clade 2.3.4.4b H5N1 since Autumn 2021. As well as impacting upon commercial and wild avian species, the virus has also infected mammalian species more than ever observed previously. Mammalian species involved in spill over events have primarily been scavenging terrestrial carnivores and farmed mammalian species although marine mammals have also been affected. Alongside reports of detections of mammalian species found dead through different surveillance schemes, several mass mortality events have been reported in farmed and wild animals. In November 2022, an unusual mortality event was reported in captive bush dogs (Speothos venaticus) with clade 2.3.4.4b H5N1 HPAIV of avian origin being the causative agent. The event involved an enclosure of 15 bush dogs, 10 of which succumbed during a nine-day period with some dogs exhibiting neurological disease. Ingestion of infected meat is proposed as the most likely infection route.
摘要：
自2021年秋季以来，欧洲遭受了前所未有的高致病性禽流感（HPAI）进化枝2.3.4.4bH5N1流行病。以及对商业和野生鸟类的影响，这种病毒也比以前观察到的更多地感染了哺乳动物。参与溢出事件的哺乳动物物种主要是清除陆地食肉动物和养殖哺乳动物，尽管海洋哺乳动物也受到了影响。除了通过不同监测方案发现死亡的哺乳动物物种的检测报告外，据报道，在养殖和野生动物中发生了几起大规模死亡事件。2022年11月，圈养丛林犬（Speothosvenaticus）报告了异常死亡事件，禽源进化枝2.3.4.4bH5N1HPAIV是病原体。该事件涉及15只丛林狗的围栏，其中十只在九天内死亡，一些狗表现出神经系统疾病。建议摄入受感染的肉作为最可能的感染途径。
