用于定量分析 APOBEC 催化的 DNA 脱氨的实时生化测定。
关键词: APOBEC3 biotechnology cancer cytidine deaminase fluorescence resonance energy transfer (FRET) high-throughput screening (HTS) mutagenesis protein-DNA interaction real-time assay somatic mutations
Mesh : Humans Deamination Cytidine Deaminase / metabolism DNA / metabolism chemistry Kinetics APOBEC Deaminases / metabolism Enzyme Inhibitors / pharmacology
来 源:
DOI:10.1016/j.jbc.2024.107410
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