关键词: Abscess; Breast diseases Microbial drug resistance Staphylococcus aureus Sulfamethoxazole

Mesh : Humans Female Cross-Sectional Studies Retrospective Studies Abscess / microbiology Adult Anti-Bacterial Agents / pharmacology therapeutic use Middle Aged Staphylococcus aureus / drug effects isolation & purification Brazil Staphylococcal Infections / microbiology drug therapy Microbial Sensitivity Tests Drug Resistance, Bacterial Breast Diseases / microbiology drug therapy Young Adult Community-Acquired Infections / microbiology drug therapy Adolescent

来  源:   DOI:10.61622/rbgo/2024rbgo34   PDF(Pubmed)

Abstract:
UNASSIGNED: The aim of this study is to evaluate the etiological profile and antimicrobial resistance in breast abscess cultures from patients from the community, treated at a public hospital located in Porto Alegre, Brazil.
UNASSIGNED: This is an retrospective cross-sectional study that evaluated the medical records of patients with bacterial isolates in breast abscess secretion cultures and their antibiograms, from January 2010 to August 2022.
UNASSIGNED: Based on 129 positive cultures from women from the community diagnosed with breast abscesses and treated at Fêmina Hospital, 99 (76.7%) of the patients had positive cultures for Staphylococcus sp, 91 (92%) of which were cases of Staphylococcus aureus. Regarding the resistance profile of S. aureus, 32% of the strains were resistant to clindamycin, 26% to oxacillin and 5% to trimethoprim-sulfamethoxazole. The antimicrobials vancomycin, linezolid and tigecycline did not show resistance for S. aureus.
UNASSIGNED: Staphylococcus aureus was the most common pathogen found in the breast abscess isolates during the study period. Oxacillin remains a good option for hospitalized patients. The use of sulfamethoxazole plus trimethoprim should be considered as a good option for use at home, due to its low bacterial resistance, effectiveness and low cost.
摘要:
本研究的目的是评估社区患者乳腺脓肿培养的病因学特征和抗菌素耐药性,在阿雷格里港的一家公立医院接受治疗,巴西。
这是一项回顾性的横断面研究,评估了乳腺脓肿分泌物培养物中细菌分离株的患者的病历及其抗菌谱,2010年1月至2022年8月。
基于来自社区的女性的129种阳性文化,这些女性被诊断患有乳腺脓肿并在费米纳医院接受治疗,99例(76.7%)患者葡萄球菌属培养阳性,其中91例(92%)为金黄色葡萄球菌。关于金黄色葡萄球菌的耐药性,32%的菌株对克林霉素耐药,26%的苯唑西林和5%的甲氧苄啶-磺胺甲恶唑。抗生素万古霉素,利奈唑胺和替加环素未显示金黄色葡萄球菌耐药。
金黄色葡萄球菌是研究期间乳腺脓肿分离株中最常见的病原体。苯唑西林仍然是住院患者的良好选择。使用磺胺甲恶唑加甲氧苄啶应被视为在家中使用的良好选择,由于细菌耐药性低,效率和低成本。
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