PDF(Pubmed)
Abstract：
OBJECTIVE: To assess the level of agreement and evaluate the reliability of measurements between two Scheimpflug imaging modalities, Scansys (MediWorks, China) and Sirius (CSO, Italy), in quantifying the anterior segment parameters in healthy eyes.
METHODS: In a cross-sectional study, the right eyes of 38 healthy participants without any ocular or systemic diseases were examined. A range of anterior segment parameters including anterior and posterior flat and steep keratometry, central corneal thickness (CCT), thinnest corneal thickness (TCT), anterior chamber depth (ACD), anterior chamber angle (ACA), corneal volume, anterior chamber volume, and horizontal white to white diameter, derived from the sagittal curvature maps were measured. To evaluate the reliability of the measurements, intraclass correlation coefficient (ICC) and correlation coefficient were measured. Additionally, Bland-Altman plots were employed to examine the agreement in mean (bias line) and 95% limits of agreement between the two devices.
RESULTS: The mean age was 31.5 ± 6.9 (range: 19-47) years. The ICC indicated that the majority of anterior segment parameters had an excellent or good level of reliability, surpassing the threshold of 0.9. Nevertheless, CCT and ACA exhibited a moderate level of reliability, with ICC values of 0.794 and 0.728, respectively. The correlation analysis showed a strong correlation for all the variables tested. The Bland-Altman plots revealed that the bias line was near zero and the 95% limits of agreement were narrow for most variables, except for the anterior flat and steep keratometry, which were found to range from - 0.57 to 0.84 D and - 0.68 to 0.87 D, respectively.
CONCLUSIONS: Scansys and Sirius devices can be effectively used interchangeably for the evaluation of most anterior segment parameters; however, for anterior corneal curvatures, CCT and ACA, their alternative use is not recommended.
METHODS: In a cross-sectional study, the right eyes of 38 healthy participants without any ocular or systemic diseases were examined. A range of anterior segment parameters including anterior and posterior flat and steep keratometry, central corneal thickness (CCT), thinnest corneal thickness (TCT), anterior chamber depth (ACD), anterior chamber angle (ACA), corneal volume, anterior chamber volume, and horizontal white to white diameter, derived from the sagittal curvature maps were measured. To evaluate the reliability of the measurements, intraclass correlation coefficient (ICC) and correlation coefficient were measured. Additionally, Bland-Altman plots were employed to examine the agreement in mean (bias line) and 95% limits of agreement between the two devices.
RESULTS: The mean age was 31.5 ± 6.9 (range: 19-47) years. The ICC indicated that the majority of anterior segment parameters had an excellent or good level of reliability, surpassing the threshold of 0.9. Nevertheless, CCT and ACA exhibited a moderate level of reliability, with ICC values of 0.794 and 0.728, respectively. The correlation analysis showed a strong correlation for all the variables tested. The Bland-Altman plots revealed that the bias line was near zero and the 95% limits of agreement were narrow for most variables, except for the anterior flat and steep keratometry, which were found to range from - 0.57 to 0.84 D and - 0.68 to 0.87 D, respectively.
CONCLUSIONS: Scansys and Sirius devices can be effectively used interchangeably for the evaluation of most anterior segment parameters; however, for anterior corneal curvatures, CCT and ACA, their alternative use is not recommended.
摘要：
目的：评估两种Scheimpflug成像方式之间的一致性水平并评估测量的可靠性，Scansys(MediWorks,中国)和天狼星(CSO，意大利),在量化健康眼睛的眼前节参数。
方法：在一项横断面研究中，对38例没有任何眼部或全身性疾病的健康参与者的右眼进行了检查.一系列眼前节参数，包括前后平坦和陡峭角膜曲率测量，中央角膜厚度(CCT),最薄角膜厚度（TCT），前房深度（ACD），前房角(ACA),角膜体积,前房容积,和水平白色到白色的直径，从矢状曲率图得到测量结果。为了评估测量的可靠性，测量组内相关系数（ICC）和相关系数。此外,Bland-Altman图用于检查两种设备之间的平均值（偏差线）和95％一致性极限的一致性。
结果：平均年龄为31.5±6.9（范围：19-47）岁。ICC表明，大多数眼前节参数具有优异或良好的可靠性水平，超过0.9的阈值。然而，CCT和ACA表现出中等程度的可靠性，ICC值分别为0.794和0.728。相关性分析显示所有测试的变量都有很强的相关性。Bland-Altman图显示，大多数变量的偏差线接近零，95％的一致性限制狭窄，除了前平坦和陡峭的角膜曲率测量，发现范围从-0.57到0.84D和-0.68到0.87D，分别。
结论：Scansys和Sirius设备可以有效地互换使用，用于评估大多数前段参数；但是，对于前角膜曲率，CCT和ACA,他们的替代使用是不建议的。
方法：在一项横断面研究中，对38例没有任何眼部或全身性疾病的健康参与者的右眼进行了检查.一系列眼前节参数，包括前后平坦和陡峭角膜曲率测量，中央角膜厚度(CCT),最薄角膜厚度（TCT），前房深度（ACD），前房角(ACA),角膜体积,前房容积,和水平白色到白色的直径，从矢状曲率图得到测量结果。为了评估测量的可靠性，测量组内相关系数（ICC）和相关系数。此外,Bland-Altman图用于检查两种设备之间的平均值（偏差线）和95％一致性极限的一致性。
结果：平均年龄为31.5±6.9（范围：19-47）岁。ICC表明，大多数眼前节参数具有优异或良好的可靠性水平，超过0.9的阈值。然而，CCT和ACA表现出中等程度的可靠性，ICC值分别为0.794和0.728。相关性分析显示所有测试的变量都有很强的相关性。Bland-Altman图显示，大多数变量的偏差线接近零，95％的一致性限制狭窄，除了前平坦和陡峭的角膜曲率测量，发现范围从-0.57到0.84D和-0.68到0.87D，分别。
结论：Scansys和Sirius设备可以有效地互换使用，用于评估大多数前段参数；但是，对于前角膜曲率，CCT和ACA,他们的替代使用是不建议的。
