目的:本研究的目的是评估用三种不同的眼前节分析系统测量的健康近视患者的中央角膜厚度(CCT)之间的相关性和一致性。
方法:这是一项回顾性研究。该研究包括2021年1月至2023年12月在我院屈光外科接受术前检查的近视患者。CCT使用Pentacam单独测量,小天狼星,IOLMaster700
方法:采用SPSS软件进行统计学分析。采用Pearson法评估三组测量值之间的相关性,并绘制了一个简单的散点图和拟合线。Bland-Altman散点图和95%的一致性(LoAs)用于评估系统之间数据的一致性。
结果:共有269名患者参与了这项研究,包括134名男性(49.8%)和135名女性(50.2%)。Pentacam的CCT测量,小天狼星,和IOLMaster700仪器被发现为541.63±31.67μm,541.74±33.36μm,和548.90±34.19μm;这些测量之间观察到显着差异(p<0.05)。Pentacam和IOLMaster700之间以及Sirius和IOLMaster700之间的CCT也观察到显着差异(p<0.05)。所有三种设备的CCT测量均显示出高度正相关,所有p值小于0.001:Pentacam和Sirius,r=0.972;Pentacam和IOLMaster700,r=0.966;Sirius和IOLMaster700,r=0.962。各自95%的LoAs分别为-0.18~0.18;-1.51~-1.11;和-1.52~-1。
结论:结果表明,使用三种不同的眼前节分析系统测量健康近视眼的CCT具有高度相关性。然而,三种设备测量的值差异具有统计学意义.因此,在实际的临床实践中,建议应使用相同的设备来测量和评估每次访问的CCT。
OBJECTIVE: The purpose of this study was to evaluate the correlations and consistency among the central corneal thickness (CCT) of healthy myopic patients measured with three different anterior segment analysis systems.
METHODS: This was a retrospective study. The study included myopia patients who had undergone preoperative examinations in the refractive surgery department of our hospital between January 2021 and December 2023. The CCT was measured separately using Pentacam,
Sirius, and IOLMaster 700.
METHODS: Statistical analysis was conducted using SPSS software. Correlations among the three groups of measured values were assessed using the Pearson method, and a simple scatter plot and fitting line were drawn. Bland‒Altman scatter plots and 95 % limits of agreement (LoAs) were used to evaluate consistency in the data among the systems.
RESULTS: A total of 269 patients participated in the study, including 134 males (49.8 %) and 135 females (50.2 %). The CCT measurements by Pentacam,
Sirius, and IOLMaster 700 instruments were found to be 541.63 ± 31.67 μm, 541.74 ± 33.36 μm, and 548.90 ± 34.19 μm respectively; significant differences were observed among these measurements (p < 0.05). Significant differences were also observed in CCT between Pentacam and IOLMaster 700 as well as between
Sirius and IOLMaster 700 (p < 0.05). The CCT measurements by all three devices showed high positive correlation with all p values less than 0.001: Pentacam and
Sirius, r = 0.972; Pentacam and IOLMaster 700, r = 0.966; and
Sirius and IOLMaster 700, r = 0.962. The respective 95 % LoAs were -0.18∼0.18; -1.51∼-1.11; and -1.52∼-1.
CONCLUSIONS: The results indicate that there is a high correlation in measuring CCT for healthy myopic eyes using three different anterior segment analysis systems. However, the differences in the values measured by the three devices were statistically significant. Therefore, in actual clinical practice, it is suggested that the same device should be used to measure and evaluate the CCT across visits.