Abstract：
OBJECTIVE: We compared the effect of 12 weeks lesser mealworm-based (Alphitobius diaperinus) protein supplementation to whey protein and placebo supplementation on Exercise-Induced Muscle Damage (EIMD) after long-distance walking in older adults.
METHODS: in this randomized controlled trial, 70 physically active older adults (>60 years) were randomly allocated to the following groups: I) lesser mealworm protein, II) whey protein or III) iso-caloric placebo. Participants received supplements 11 weeks before and 1 week during a 3-day long-distance walking challenge (30-50 km per day). Blood concentrations of creatinine kinase (CK) and lactate dehydrogenase (LDH), handgrip strength and muscle soreness were measured pre-exercise and directly after each walking bout.
RESULTS: Significant elevations of CK concentrations (103 [76-161] U/l to 758 [342-1104] U/l, p < 0.001) and LDH concentrations (202 [175-220] to 283 [252-339] U/l, p < 0.001) were observed following 7h45 min ± 11 min of walking exercise per day, but the magnitude of this effect did not differ among suppletion groups. Hand grip strength decreased significantly (p < 0.001) while muscle soreness increased (p = 0.002) after the first walking day compared to pre-exercise, with no group differences.
CONCLUSIONS: 12-weeks of lesser mealworm-based protein supplementation (30 g/day) does not attenuate exercise induced muscle damage in older adults following three days of prolonged walking exercise in comparison to placebo or whey protein.
METHODS: in this randomized controlled trial, 70 physically active older adults (>60 years) were randomly allocated to the following groups: I) lesser mealworm protein, II) whey protein or III) iso-caloric placebo. Participants received supplements 11 weeks before and 1 week during a 3-day long-distance walking challenge (30-50 km per day). Blood concentrations of creatinine kinase (CK) and lactate dehydrogenase (LDH), handgrip strength and muscle soreness were measured pre-exercise and directly after each walking bout.
RESULTS: Significant elevations of CK concentrations (103 [76-161] U/l to 758 [342-1104] U/l, p < 0.001) and LDH concentrations (202 [175-220] to 283 [252-339] U/l, p < 0.001) were observed following 7h45 min ± 11 min of walking exercise per day, but the magnitude of this effect did not differ among suppletion groups. Hand grip strength decreased significantly (p < 0.001) while muscle soreness increased (p = 0.002) after the first walking day compared to pre-exercise, with no group differences.
CONCLUSIONS: 12-weeks of lesser mealworm-based protein supplementation (30 g/day) does not attenuate exercise induced muscle damage in older adults following three days of prolonged walking exercise in comparison to placebo or whey protein.
摘要：
目的：我们比较了12周小粉虫（Alphitobiusdiaperinus）蛋白质补充剂、乳清蛋白补充剂和安慰剂补充剂对老年人长距离步行后运动性肌肉损伤（EIMD）的影响。
方法：在这项随机对照试验中，70名身体活跃的老年人（>60岁）被随机分配到以下组中：I）较小的粉虫蛋白，II)乳清蛋白或III)等热量安慰剂。参与者在为期3天的长距离步行挑战（每天30-50公里）前11周和1周接受补充剂。肌酐激酶（CK）和乳酸脱氢酶（LDH）的血液浓度，在运动前和每次步行后直接测量握力和肌肉酸痛。
结果：CK浓度显着升高（103[76-161]U/l至758[342-1104]U/l，p<0.001）和LDH浓度（202[175-220]至283[252-339]U/l，p<0.001)在每天7h45分钟±11分钟的步行运动后观察到，但是这种影响的程度在补给组之间没有差异。与运动前相比，步行第一天后，手握力显着下降（p<0.001），而肌肉酸痛增加（p=0.002）。没有群体差异。
结论：与安慰剂或乳清蛋白相比，在延长3天的步行运动后，补充12周小粉虫为基础的蛋白质（30克/天）并不能减轻老年人运动诱发的肌肉损伤。
方法：在这项随机对照试验中，70名身体活跃的老年人（>60岁）被随机分配到以下组中：I）较小的粉虫蛋白，II)乳清蛋白或III)等热量安慰剂。参与者在为期3天的长距离步行挑战（每天30-50公里）前11周和1周接受补充剂。肌酐激酶（CK）和乳酸脱氢酶（LDH）的血液浓度，在运动前和每次步行后直接测量握力和肌肉酸痛。
结果：CK浓度显着升高（103[76-161]U/l至758[342-1104]U/l，p<0.001）和LDH浓度（202[175-220]至283[252-339]U/l，p<0.001)在每天7h45分钟±11分钟的步行运动后观察到，但是这种影响的程度在补给组之间没有差异。与运动前相比，步行第一天后，手握力显着下降（p<0.001），而肌肉酸痛增加（p=0.002）。没有群体差异。
结论：与安慰剂或乳清蛋白相比，在延长3天的步行运动后，补充12周小粉虫为基础的蛋白质（30克/天）并不能减轻老年人运动诱发的肌肉损伤。
