关键词: Automated insulin delivery Closed-loop Glucose control Insulin pump Insulin therapy MiniMed™ Time in tight range

Mesh : Humans Hypoglycemic Agents / therapeutic use Insulin / therapeutic use Goals Insulin Infusion Systems Diabetes Mellitus, Type 1 / drug therapy Blood Glucose Blood Glucose Self-Monitoring

来  源:   DOI:10.1089/dia.2023.0432   PDF(Pubmed)

Abstract:
The concept of maintaining blood glucose levels within the 70-180 mg/dL range, known as time-in-range, has raised questions regarding its representation of true physiological euglycemia. Some have speculated that focusing on the time spent within the 70-140 mg/dL range, introduced as time in tight range (TITR) through the International Consensus statement, could serve as a more precise metric for assessing normoglycemia in individuals with type 1 diabetes. This article delves into the current status of TITR as an emerging marker and explores how advanced hybrid closed-loop systems may offer a promising avenue for achieving this higher level of glycemic control.
摘要:
将血糖水平维持在70-180mg/dL范围内的概念,被称为时间范围,提出了有关其真实生理正常血糖表示的问题。一些人推测,专注于在70-140毫克/分升范围内花费的时间,通过国际共识声明,作为时间在严格范围内(TITR)引入,可以作为评估1型糖尿病患者血糖正常的更精确指标。本文深入研究了TITR作为新兴标志物的现状,并探讨了先进的混合闭环系统如何为实现更高水平的血糖控制提供了有希望的途径。
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