PDF(Pubmed)
Abstract：
Impetigo herpetiformis is a rare skin disease that most often occurs in the third trimester of pregnancy. It is currently considered as a form of generalized pustular psoriasis and the typical skin lesions comprise small sterile pustules. Here, a case of impetigo herpetiformis in the second trimester of pregnancy after 7 weeks of hydroxychloroquine administration for suspected Sjogren\'s syndrome is reported. Treatment with anti-infective, anti-inflammatory and immunosuppressive medication did not improve the patient\'s condition. Following delivery of a live male by emergency caesarean section at 29 weeks\' gestation, the rash was reported to be completely resolved by 3 months postpartum. Previously published cases of impetigo herpetiformis in the second trimester of pregnancy that were retrieved from a search of the PubMed database are also reviewed and discussed.
摘要：
脓疱疮是一种罕见的皮肤病，最常见于妊娠晚期。目前认为它是全身性脓疱型银屑病的一种形式,典型的皮肤损伤包括小的无菌脓疱。这里,报告1例妊娠中期因疑似干燥综合征服用羟氯喹7周后出现疱疹样脓疱病。抗感染治疗,抗炎和免疫抑制药物并未改善患者的病情。在妊娠29周时通过紧急剖腹产分娩一名活着的男性后，据报道，皮疹在产后3个月时完全消退。还审查并讨论了从PubMed数据库搜索中检索到的先前发表的妊娠中期脓疱病的病例。
