面筋,多肽半抗原,在许多谷物中发现,如大麦,小麦,黑麦,燕麦,和其他人,最近与一系列皮肤疾病有关,从慢性斑块状银屑病到银屑病关节炎,荨麻疹(慢性和儿科发作),和扁平苔藓的血管性水肿,白癜风,还有酒渣鼻.他们的证据仍然没有得到很好的审查。为谷蛋白在各种皮肤病中的因果作用提供证据。Pubmed,MedLine,和EMBASE数据库使用关键字“麸质”和一种皮肤病进行搜索,即,“特应性皮炎”,\"血管炎\",\"牛皮癣\",“牛皮癣关节炎”,\"痤疮\",\"斑秃\",和“免疫性疾病”。考虑了所有以英文发表的文章,这些文章有免费全文。搜索策略总共返回了1487篇文章,对其进行了相关性和重复的消除筛选。最终,大约有114篇文章被认为是合适的。数据被提取并以叙述性综述格式呈现。对于许多这些慢性和终身疾病,一个简单且具有成本效益的解决方案是限制饮食中的麸质。然而,皮肤科医生最好记住,在包括这里列出的绝大多数皮肤病中,麸质限制是没有必要的,甚至可能导致营养缺乏。证据从牛皮癣关节炎等疾病的I级到IV级,再到痤疮等大多数疾病,白癜风,血管炎,和特应性皮炎。在这里,我们回顾了每种情况的证据,并对其中的麸质限制提出了切实可行的建议。
Gluten, a polypeptide hapten, found in many cereals such as barley, wheat, rye, oats, and others, has been recently implicated in a range of cutaneous disorders ranging from chronic plaque psoriasis through psoriatic arthritis, urticaria (chronic as well as paediatric onset), and angioedema to lichen planus, vitiligo, and rosacea. The evidence for them is still not well reviewed. To generate evidence for the causal role of gluten in various dermatological disorders. The Pubmed, MedLine, and EMBASE databases were searched using the keywords \"Gluten\" and one of the dermatoses, namely, \"Atopic Dermatitis\", \"Vasculitis\", \"Psoriasis\", \"Psoriatic Arthritis\", \"Acne\", \"Alopecia Areata\", and \"Immunobullous disorders\". All articles published in English for which free full text was available were taken into consideration. The search strategy returned in a total of 1487 articles which were screened for relevance and elimination of duplicates. Ultimately, around 114 articles were deemed suitable. The data were extracted and presented in the narrative review format. A simple and cost-effective solution to many of these chronic and lifelong conditions is to restrict gluten in the diet. However, the dermatologist would do well to remember that in the vast majority of dermatological disorders including the ones listed here, gluten restriction is not warranted and can even lead to nutritional deficiencies. The evidence varied from Grade I for some disorders like psoriatic arthritis to Grade IV to most disorders like acne, vitiligo, vasculitis, and atopic dermatitis. Herein, we review the evidence for each of these conditions and make practical recommendations for gluten restriction in them.